Products from Innaxon
Innaxon is a company based in Tewkesbury, United Kingdom focussing on innate immunity, Toll-like Receptor (TLR) agonists and small molecule inhibitors. Innaxon develops and manufactures defined “Immunoceuticals” of the highest activity and purity for pre-clinical research and development applications for vaccine adjuvants and immunotherapy. Their unique biological and synthetic TLR ligands are well-characterized and effective biological response modifiers of inappropriate or disproportionate immune responses.
More information at: www.adipogen.com/innaxon
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IAXO-101 (CD14/TLR4 Antagonist) (synthetic)
Item number: IAX-600-001-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Keywords: | Methyl 6-deoxy-6-N-dimethyl-N-cyclopentylammonium-2,3-di-O-tetradecyl-?-D-glucopyranoside iodide |
| Application: | CD14/TLR4 Antagonist |
| CAS | 1202388-64-4 |
| MW: | 810.02 D |
358.00€
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ODN 2395 (Type C) Endotoxin-free (sterile)
Item number: IAX-200-007-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: Neutral-ODN (Cat. No.: IAX-200-202).
| Keywords: | CpG ODN: C Type (species: human and rodent) |
| Application: | TLR9 activator |
| MW: | 7068 D |
From 191.00€
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LPS from E. coli R515 (Re) TLRpure Sterile Solution
Item number: IAX-100-007-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from E. coli strain R515 (Re), R-type (rough/mutant) LPS |
| Application: | TLR4 activator |
From 172.00€
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LPS (Universal) from S. abortus equi (S-form) TLRpure...
Item number: IAX-100-009-M001
Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid differentiation protein 2 (MD-2). According to current consensus activation of TLR4 is preceded by the transfer of LPS to membrane-bound (m) or soluble (s) CD14 by...
| Keywords: | Lipopolysaccharide (LPS) from Salmonella abortus equi, S-type (smooth/wild-type) LPS |
| Application: | TLR4 activator |
From 154.00€
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ODN 1826 (Type B) Endotoxin-free (sterile)
Item number: IAX-200-002-M001
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1982 (Cat. No.: IAX-200-201).
| Keywords: | CpG ODN TLR9 Agonist: B Type (species: rodent) |
| Application: | TLR9 activator |
| Species reactivity: | mouse, rat |
| MW: | 6383 D |
From 191.00€
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ODN 2006 (Type B) Endotoxin-free (sterile)
Item number: IAX-200-006-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2137 (Cat. No.: IAX-200-206).
| Keywords: | CpG ODN TLR9 Agonist: B Type (species: human and rodent) |
| Application: | TLR9 activator |
| MW: | 7720 D |
From 191.00€
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Lipid A from E. coli R515 (Re) TLRpure Sterile Solution
Item number: IAX-100-004-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly...
| Keywords: | Lipid A derived from E. coli R515 (Re) LPS (biosynthetic) |
| Application: | TLR4 activator |
From 153.00€
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LPS from E. coli O8:K27 (S-form) TLRpure Sterile Solution
Item number: IAX-100-006-M001
Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid differentiation protein 2 (MD-2). According to current consensus activation of TLR4 is preceded by the transfer of LPS to membrane-bound (m) or soluble (s) CD14 by...
| Keywords: | Lipopolysaccharide (LPS) from E. coli O8:K27, S-type (smooth/wild-type) LPS |
| Application: | TLR4 activator |
From 124.00€
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LPS from S. minnesota R7 (Rd1) TLRpure Sterile Solution
Item number: IAX-100-018-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.05-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from S. minnesota strain R7 (Rd1), R-type (rough/mutant) LPS |
| Application: | TLR4 activator |
From 172.00€
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LPS from S. enteritidis (S-form) TLRpure Sterile Solution
Item number: IAX-100-019-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from Salmonella enteritidis, S-type (smooth/wild-type) LPS |
| Application: | TLR4 activator |
From 202.00€
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LPS from S. minnesota (S-form) TLRpure Sterile Solution
Item number: IAX-100-020-M001
Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal...
| Keywords: | Lipopolysaccharide (LPS) from Salmonella minnesota, S-type (smooth/wild-type) LPS |
| Application: | TLR4 activator |
From 172.00€
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ODN 2216 (Type A) Endotoxin-free (sterile)
Item number: IAX-200-005-C100
3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
| Keywords: | CpG ODN TLR9 Agonist: A Type (species: human and rodent) |
| Application: | TLR9 activator |
| MW: | 6644 D |
From 191.00€
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