Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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TRAIL R2/DR5/TNFRSF10B hFc Chimera, Human
Item number: GSC-Z05912-100
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling...
| Keywords: | TNFRSF10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily... |
| Origin: | human |
| MW: | 41.1 kD |
From 376.00€
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Transferrin, His, Human
Item number: GSC-Z05917-100
Transferrin (Tf), an iron transporter, is mainly biosynthesized in the liver, but can also be biosynthesized in the brain, i.e., by oligodendrocytes and the choroid plexus, a cerebrospinal fluid (CSF) producing tissue. The CSF contains two Tf isoforms, brain-type Tf and serum-type Tf, which differ in their glycan...
| Keywords: | TF, Siderophilin, Serotransferrin, Beta-1 metal-binding globulin |
| Origin: | human |
| MW: | 76.3 kD |
From 255.00€
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Transferrin R/CD71 hFc Chimera, Human
Item number: GSC-Z05918-100
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of...
| Keywords: | T9, p90, TFRC, Transferrin receptor protein 1 |
| Origin: | human |
| MW: | 101.8 kD |
From 376.00€
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TSPAN8 hFc Chimera, Human
Item number: GSC-Z05933-100
Tetraspanin 8 (TSPAN8) is a member of the tetraspanin superfamily that forms TSPAN8-mediated protein complexes by interacting with themselves and other various cellular signaling molecules.In physiological conditions, TSPAN8 plays a vital role in the regulation of biological functions, including leukocyte...
| Keywords: | TSPAN8, Tetraspanin-8, Tumor-associated antigen CO-029, Transmembrane 4 superfamily member 3 |
| Origin: | human |
| MW: | 37.3 kD |
From 457.00€
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TYRO3, His, Human
Item number: GSC-Z05936-100
The TAM receptors (Tyro3, Axl and MerTK) are promising therapeutic targets on tumor-associated macrophages. The TAM receptors are a family of receptor tyrosine kinases with shared ligands Gas6 and Protein S that skew macrophage polarization towards a pro-tumor M2-like phenotype.In macrophages, the TAM receptors also...
| Keywords: | TYRO3, Tyrosine-protein kinase SKY, Tyrosine-protein kinase RSE, Tyrosine-protein kinase BYK, Tyrosine-protein kinase TIF,... |
| Origin: | human |
| MW: | 42.8 kD |
From 255.00€
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ULBP-2, His & Avi, Human
Item number: GSC-Z05940-100
ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway, mediating natural killer cell cytotoxicity.
| Keywords: | ULBP2, ALCAN-alpha, NKG2D ligand 2, UL16-binding protein 2, Retinoic acid early transcript 1H |
| Origin: | human |
| MW: | 24.6 kD |
From 336.00€
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ULBP-6 hFc Chimera, Human
Item number: GSC-Z05942-100
ULBP6/RAET1L (UL16-binding protein, also known as retinoic acid early transcript), is expressed as a full-lengthtranscript in cells and encodes a protein that is a ligand for bothNKG2D and the UL16 protein of HCMV.
| Keywords: | RAET1L, UL16-binding protein 6, Retinoic acid early transcript 1L protein |
| Origin: | human |
| MW: | 48.61 kD |
From 524.00€
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uPAR/PLAUR hFc Chimera, Human
Item number: GSC-Z05947-100
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
| Keywords: | PLAUR, Monocyte activation antigen Mo3, Urokinase plasminogen activator surface receptor |
| Origin: | human |
| MW: | 58.2 kD |
From 228.00€
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VAP-1, His, Human
Item number: GSC-Z05948-100
The semicarbazide-sensitive amine oxidase (SSAO), also known as vascular adhesion protein-1 (VAP-1) or primary amine oxidase (PrAO), is a deaminating enzyme highly expressed in vessels that generates harmful products as a result of its enzymatic activity. As a multifunctional enzyme, it is also involved in...
| Keywords: | AOC3, HPAO, Copper amine oxidase, Vascular adhesion protein 1, Amine oxidase copper-containing 3, Amine oxidase... |
| Origin: | human |
| MW: | 82.88 kD |
From 457.00€
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VCAM-1/CD106 hFc Chimera, Human
Item number: GSC-Z05949-100
Tumor necrosis factor alpha (TNFalpha) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFalpha induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was...
| Keywords: | VCAM1, INCAM-100, Vascular cell adhesion protein 1 |
| Origin: | human |
| MW: | 100.17 kD |
From 336.00€
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VCAM-1/CD106, His, Human
Item number: GSC-Z05950-100
Tumor necrosis factor alpha (TNFalpha) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFalpha induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was...
| Keywords: | VCAM1, INCAM-100, Vascular cell adhesion protein 1 |
| Origin: | human |
| MW: | 75.2 kD |
From 336.00€
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VSIG3/IGSF11, His, Human
Item number: GSC-Z05959-100
Immunoglobulin superfamily member 11 (IgSF11), a homophilic adhesion molecule that preferentially expressed in the brain, is a dual-binding partner of the postsynaptic scaffolding protein PSD-95 and AMPA glutamate receptors (AMPARs).
| Keywords: | IGSF11, Immunoglobulin superfamily member 11, V-set and immunoglobulin domain-containing protein 3, Brain and... |
| Origin: | human |
| MW: | 24.31 kD |
From 457.00€
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