TRAIL R2/DR5/TNFRSF10B hFc Chimera, Human

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z05912-100	100 µg		-		7 - 10 business days*		376.00€
GSC-Z05912-500	500 µg		-		7 - 10 business days*		1,263.00€

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DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane... more

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Product information "TRAIL R2/DR5/TNFRSF10B hFc Chimera, Human"

DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.

Keywords:	TNFRSF10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, Tumor necrosis factor receptor superfamily member 10B
Supplier:	GenScript
Supplier-Nr:	Z05912

Properties

Conjugate:	No
Species reactivity:	human
MW:	41.1 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

KEGG ID :	K04722 \| Matching products
UniProt ID :	O14763 \| Matching products
Gene ID :	GeneID 8795 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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