Products from GenScript
GenScript Biotech Corporation is a leading global provider of research products supporting life science innovation. Their extensive portfolio includes custom genes, peptides, proteins, antibodies, and oligonucleotides, along with a wide range of CRISPR tools, cloning vectors, expression systems, and cell culture reagents. With high-quality standards and reliable delivery, GenScript enables researchers worldwide to accelerate discoveries across molecular biology, immunology, and drug development.
More information at: www.genscript.com
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Serum Albumin, His, Cynomolgus
Item number: GSC-Z04911-100
Albumins are multifunctional proteins present in the blood serum of animals. They can bind and transport a wide variety of ligands which they accommodate due to their conformational flexibility. Serum albumins are highly conserved both in amino acid sequence and three-dimensional structure. Several mammalian and...
| Keywords: | ALB, Albumin |
| Origin: | cynomolgus |
| MW: | 67.1 kD |
From 296.00€
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SEZ6, His, Cynomolgus
Item number: GSC-Z04912-100
Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the beta-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in...
| Keywords: | SEZ6 |
| Origin: | cynomolgus |
| MW: | 99.11 kD |
From 524.00€
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SG3/Secretogranin 3, His, Cynomolgus
Item number: GSC-Z04914-100
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are...
| Keywords: | SCG3, Secretogranin-3, Secretogranin III |
| Origin: | cynomolgus |
| MW: | 52.14 kD |
From 524.00€
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TLR3, His, Cynomolgus
Item number: GSC-Z04926-100
TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to...
| Keywords: | TLR3, Toll-like receptor 3 |
| Origin: | cynomolgus |
| MW: | 78.04 kD |
From 524.00€
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TNF alpha, His, Cynomolgus
Item number: GSC-Z04927-100
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism.Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It...
| Keywords: | TNF, TNF-alpha, Cachectin, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2 |
| Origin: | cynomolgus |
| MW: | 18.35 kD |
From 524.00€
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TNFR1/CD120a/TNFRSF1A, His, Cynomolgus
Item number: GSC-Z04928-100
Tumour necrosis factor alpha (TNF-alpha) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and...
| Keywords: | p60, p55, TNFRSF1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, Tumor necrosis factor... |
| Origin: | cynomolgus |
| MW: | 21.62 kD |
From 524.00€
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TPBG/5T4, His, Cynomolgus
Item number: GSC-Z04930-100
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs.
| Keywords: | TPBG, Trophoblast glycoprotein, Wnt-activated inhibitory factor 1 |
| Origin: | cynomolgus |
| MW: | 35.95 kD |
From 524.00€
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TRAIL R2/DR5/TNFRSF10B, His, Cynomolgus
Item number: GSC-Z04932-100
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates...
| Keywords: | TNFRSF10B |
| Origin: | cynomolgus |
| MW: | 18.28 kD |
From 376.00€
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Transferrin R/CD71, His, Cynomolgus
Item number: GSC-Z04933-100
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of...
| Keywords: | TFRC, Transferrin receptor protein 1 |
| Origin: | cynomolgus |
| MW: | 76.3 kD |
From 336.00€
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Transthyretin/Prealbumin, His, Cynomolgus
Item number: GSC-Z04934-100
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known, however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial...
| Keywords: | TTR, Prealbumin, Transthyretin |
| Origin: | cynomolgus |
| MW: | 14.8 kD |
From 524.00€
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TREM1, His, Cynomolgus
Item number: GSC-Z04935-100
TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear.
| Keywords: | TREM1, Triggering receptor expressed on myeloid cells 1 |
| Origin: | cynomolgus |
| MW: | 23.76 kD |
From 497.00€
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uPAR/PLAUR, His, Cynomolgus
Item number: GSC-Z04940-100
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen.Regulation of the activity of u-PA is also mediated by u-PAR.
| Keywords: | PLAUR, Urokinase plasminogen activator surface receptor |
| Origin: | cynomolgus |
| MW: | 32.69 kD |
From 376.00€
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