TNF alpha, His, Cynomolgus

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
GSC-Z04927-100	100 µg		-		7 - 10 business days*		524.00€
GSC-Z04927-500	500 µg		-		7 - 10 business days*		1,761.00€

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Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic... more

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Product information "TNF alpha, His, Cynomolgus"

Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism.Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.

Keywords:	TNF, TNF-alpha, Cachectin, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2
Supplier:	GenScript
Supplier-Nr:	Z04927

Properties

Conjugate:	No
Species reactivity:	cynomolgus
MW:	18.35 kD
Purity:	>95% (Bis-Tris PAGE)

Database Information

UniProt ID :

P79337 | Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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