Anti-phospho-PBK (Thr9)

Anti-phospho-PBK (Thr9)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ELK-ES6791.50 50 µl - -

10 - 14 Werktage*

169,00 €
ELK-ES6791.100 100 µl - -

10 - 14 Werktage*

283,00 €
 
PDZ binding kinase(PBK) Homo sapiens This gene encodes a serine/threonine protein kinase related... mehr
Produktinformationen "Anti-phospho-PBK (Thr9)"
PDZ binding kinase(PBK) Homo sapiens This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin- induced DNA damage. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.. Cellular localization: nucleus,
Schlagworte: Anti-phospho-PBK, Anti-phospho-SPK, Anti-phospho-TOPK, Anti-phospho-CT84, Anti-phospho-Nori-3, EC=2.7.12.2, Anti-phospho-PDZ-binding kinase, Anti-phospho-Cancer/testis antigen 84, Anti-phospho-MAPKK-like protein kinase, Anti-phospho-T-LAK cell-originated
Hersteller: ELK Biotechnology
Hersteller-Nr: ES6791

Eigenschaften

Anwendung: WB, IHC, IF, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, rat, mouse,
Immunogen: The antiserum was produced against synthesized peptide derived from human PBK/TOPK around the phosphorylation site of Thr9. AA range:1-50
MW: 36 kD
Format: Antiserum

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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