Zu "K08865" wurden 72 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-phospho-PBK (Thr9) / PDZ binding kinase, clone 30P33
Artikelnummer: NSJ-FY12793
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-PBK (Thr9) antibody detects PDZ binding kinase, also known as lymphokine activated killer T cell origin protein kinase (TOPK), when phosphorylated at threonine 9. PBK is encoded by the PBK gene...
| Schlagworte: | Anti-phospho-PBK, Anti-phospho-Nori-3, Anti-phospho-PDZ-binding kinase, Anti-phospho-Cancer/testis antigen 84,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-PDK/PDZ binding kinase/TOPK Monoclonal Antibody
Artikelnummer: E-AN200065P.100
This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support...
| Schlagworte: | SPK, PBK, TOPK, CT84, Nori-3, EC=2.7.12.2, PDZ-binding kinase, Cancer/testis antigen 84, MAPKK-like protein kinase, T-LAK... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 153,00 €
OTS964 (hydrochloride)
Artikelnummer: Cay17052-5
OTS964 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK, IC50 = 28 nM). It specifically blocks cytokinesis, leading to apoptosis, in a broad range of cancer cells. OTS964 induces apoptosis of human lung cancer cells in mouse xenografts.Formal Name:...
| Schlagworte: | 9-[4-[(1R)-2-(dimethylamino)-1-methylethyl]phenyl]-8-hydroxy-6-methyl-thieno[2,3-c]quinolin-4(5H)-one, monohydrochloride |
| Anwendung: | PBK / TOPK inhibitor |
| CAS | 1338545-07-5 |
| MW: | 429 D |
ab 76,00 €
OTS-964
Artikelnummer: LKT-O783720.25
inhibitor of T-lymphokine-activated killer cell-originated protein kinase (TOPK).
| Anwendung: | TOPK inhibitor |
| CAS | 1338545-07-5 |
| MW: | 378.49 D |
ab 188,00 €
HI TOPK 032
Artikelnummer: Cay19815-5
HI TOPK 032 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK), blocking phosphorylation of the substrate histone H2AX with an IC50 value of ~2 µM and providing complete inhibition at 5 µM. It also inhibits checkpoint kinase 1 (Chk1, IC50 = 9.6 µM). In addition, HI TOPK 032...
| Schlagworte: | N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)-2-thiophenecarboxamide |
| Anwendung: | PBK inhibitor |
| CAS | 487020-03-1 |
| MW: | 369.4 D |
ab 54,00 €
Anti-PBK
Artikelnummer: A302-194A
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
| Schlagworte: | Anti-PBK, Anti-SPK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-PBK
Artikelnummer: A302-195A
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
| Schlagworte: | Anti-PBK, Anti-SPK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-PBK
Artikelnummer: NSJ-R31723
0.5mg/ml if reconstituted with 0.2ml sterile DI water. PDZ binding kinase (PBK), also known as TOPK, is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. PBK can mediate cell growth through histone H3 modification. Evidence suggests that mitotic...
| Schlagworte: | Anti-SPK, Anti-PBK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
| Anwendung: | WB, IHC (paraffin), IF/ICC, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-PBK / TOPK
Artikelnummer: ARG57886.100
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
| Schlagworte: | Anti-SPK, Anti-PBK, Anti-TOPK, Anti-CT84, Anti-Nori-3, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-Cancer/testis antigen... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
707,00 €
OTS514
Artikelnummer: Cay17053-1
OTS514 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK, IC50 = 2.6 nM), a serine-threonine kinase often overexpressed and transactivated in several types of cancer. OTS514 (10 nM) selectively inhibits growth of patient-derived acute myeloid leukemia (AML) cells over normal CD34+...
| Schlagworte: | 9-[4-[(1R)-2-amino-1-methylethyl]phenyl]-8-hydroxy-6-methyl-thieno[2,3-c]quinolin-4(5H)-one |
| Anwendung: | TOPK inhibitor |
| CAS | 1338540-63-8 |
| MW: | 364.5 D |
ab 144,00 €
Anti-phospho-PBK / TOPK (Thr9)
Artikelnummer: ARG57923.100
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage. [The UniProt...
| Schlagworte: | Anti-phospho-PBK, Anti-phospho-SPK, Anti-phospho-CT84, Anti-phospho-TOPK, Anti-phospho-Nori-3, EC=2.7.12.2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-PBK / TOPK
Artikelnummer: ARG57922.100
Protein function: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization. [The UniProt Consortium]
| Schlagworte: | Anti-Pbk, Anti-Topk, EC=2.7.12.2, Anti-PDZ-binding kinase, Anti-T-LAK cell-originated protein kinase,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
616,00 €