Anti-phospho-CaMKII (Thr286) (HRP), clone 22B1

Anti-phospho-CaMKII (Thr286) (HRP), clone 22B1
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ARG24137.50 50 µg - -

6 - 14 Werktage*

536,00 €
 
Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after... mehr
Produktinformationen "Anti-phospho-CaMKII (Thr286) (HRP), clone 22B1"
Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (PubMed:15312654). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity. Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity. [The UniProt Consortium]
Schlagworte: Anti-phospho-Camk2a, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaM kinase II subunit alpha, Anti-phospho-CaM kinase II subunit alpha, Anti-phospho-Calcium/calmodulin-dependent protein kinase type II subunit alpha
Hersteller: Arigo Biolaboratories
Hersteller-Nr: ARG24137

Eigenschaften

Anwendung: ELISA, ICC, IF, Immunohistochemistry, IP, WB
Antikörper-Typ: Monoclonal
Klon: 22B1
Konjugat: HRP
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
Immunogen: Phosphospecific peptide around Thr286 of Rat CaMKII (NP_037052.1)
MW: 54 kD
Format: Purified

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: °C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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