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KN-93
KN-93

Artikelnummer: Cay13319-1

KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). More...
Schlagworte: N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-benzenesulfonamide
Anwendung: CaMKII inhibitor
CAS 139298-40-1
MW: 501 D
ab 108,00 €
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KN-92 (hydrochloride)
KN-92 (hydrochloride)

Artikelnummer: Cay9000890-1

KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII). At concentrations up to 25 µM, KN-92 is ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts. It is intended to be used as a control compound in studies designed to...
Schlagworte: 2-[N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, monohydrochloride
Anwendung: CaMKII inhibitor
CAS 1431698-47-3
MW: 493.4 D
ab 108,00 €
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KN-93 (water soluble)
KN-93 (water soluble)

Artikelnummer: AG-CR1-0065-M001

Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor.
Schlagworte: KN-93 . H3PO4, 2-[N-(2-Hydroxyethyl)-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine . H3PO4
Anwendung: Ca2 dependent protein kinase II inhibitor
MW: 501 D
ab 50,00 €
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KN-62
KN-62

Artikelnummer: Cay13318-5

KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII, IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).
Schlagworte: 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester,...
Anwendung: CAMKII inhibitor
CAS 127191-97-3
MW: 721.9 D
ab 49,00 €
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KN-93 (phosphate)
KN-93 (phosphate)

Artikelnummer: Cay21472-1

KN-93 (phosphate) is a potent and selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII) (Ki = 370 nM), inhibiting both the alpha- and beta-subunits of CaMKII. It does not have significant effects on cAMP-dependent protein kinase, Ca2+/phospholipid-dependent protein kinase, myosin light chain kinase, or...
Schlagworte: N-[2-[[[(2E)-3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-benzenesulfonamide,...
Anwendung: CaMKII inhibitor
CAS 1188890-41-6
MW: 599 D
ab 32,00 €
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Anti-phospho-CaMKII (Thr286)
Anti-phospho-CaMKII (Thr286)

Artikelnummer: ARG52238.50

Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates...
Schlagworte: Anti-phospho-Camk2a, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaM kinase II subunit alpha,...
Anwendung: WB
Reaktivität: Rat
467,00 €
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Anti-phospho-CaM Kinase II (Thr286)
Anti-phospho-CaM Kinase II (Thr286)

Artikelnummer: 612-401-C71

Anti-CaM Kinase II pT286 Antibody is directed against CaM Kinase II protein phosphorylated at T286. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific...
Schlagworte: Anti-phospho-Camk2a, EC=2.7.11.17, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaM kinase II subunit alpha,...
Anwendung: ELISA, WB
Reaktivität: Rat
489,00 €
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NEU
CaMK2 beta/gamma BioAssay(TM) ELISA Kit
CaMK2 beta/gamma BioAssay(TM) ELISA Kit

Artikelnummer: 471815.96

Sample Type:, Cell line of choice, Intended Use: The CaMK2 beta/gamma Colorimetric Cell-Based ELISA allows for qualitative detection of CaMK2beta/gamma in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human, Mouse, Rat, Detection Method: Colorimetric 450 nm, Format:...
Schlagworte: CAMK, CAMK2G, EC=2.7.11.17, CaMK-II subunit gamma, CaM kinase II subunit gamma, Calcium/calmodulin-dependent protein...
Anwendung: ELISA
Reaktivität: Human
715,00 €
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NEU
CaMK2-beta/gamma/delta BioAssay(TM) ELISA Kit
CaMK2-beta/gamma/delta BioAssay(TM) ELISA Kit

Artikelnummer: 471816.96

Sample Type:, Cell line of choice, Intended Use: The CaMK2-beta/gamma/delta Colorimetric Cell-Based ELISA Kit allows for qualitative detection of CaMK2-beta/gamma/delta in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human, Mouse, Rat, Detection Method: Colorimetric 450...
Schlagworte: CAM2, CAMK2B, EC=2.7.11.17, CaMK-II subunit beta, CaM kinase II subunit beta, Calcium/calmodulin-dependent protein kinase...
Anwendung: ELISA
Reaktivität: Human
715,00 €
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NEU
CAMK2A/CAMK2D BioAssay(TM) ELISA Kit
CAMK2A/CAMK2D BioAssay(TM) ELISA Kit

Artikelnummer: 471817.96

Sample Type:, Cell line of choice, Intended Use: The CAMK2A/CAMK2D Colorimetric Cell-Based ELISA Kit allows for qualitative detection of CAMK2A/CAMK2D in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human, Mouse, Rat, Detection Method: Colorimetric 450 nm, Format:...
Schlagworte: CAMKA, CAMK2A, CaMK-II subunit alpha, CaM kinase II subunit alpha, Calcium/calmodulin-dependent protein kinase type II...
Anwendung: ELISA
Reaktivität: Human
715,00 €
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NEU
Phospho-CaMK2-beta/gamma/delta (Thr287) BioAssay(TM) ELISA Kit
Phospho-CaMK2-beta/gamma/delta (Thr287) BioAssay(TM)...

Artikelnummer: 472889.192

Sample Type:, Cell line of choice, Intended Use: The Phospho-CaMK2-beta/gamma/delta (Thr287) Colorimetric Cell-Based ELISA Kit allows for qualitative detection of Phospho-CaMK2-beta/gamma/delta(Thr287) in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human:T287, Mouse:T287,...
Schlagworte: CAM2, CAMK2B, EC=2.7.11.17, CaMK-II subunit beta, CaM kinase II subunit beta, Calcium/calmodulin-dependent protein kinase...
Anwendung: ELISA
Reaktivität: Human
812,00 €
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NEU
Phospho-CAMK2A/CAMK2D (Thr286) BioAssay(TM) ELISA Kit
Phospho-CAMK2A/CAMK2D (Thr286) BioAssay(TM) ELISA Kit

Artikelnummer: 472890.192

Sample Type:, Cell line of choice, Intended Use: The Phospho-CAMK2A/CAMK2D (Thr286) Colorimetric Cell-Based ELISA Kit allows for qualitative detection of Phospho-CAMK2A/CAMK2D(Thr286) in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human:T286/287, Mouse:T286/287,...
Schlagworte: CAMKA, CAMK2A, CaMK-II subunit alpha, CaM kinase II subunit alpha, Calcium/calmodulin-dependent protein kinase type II...
Anwendung: ELISA
Reaktivität: Human
812,00 €
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