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KN-93 Artikelnummer: Cay13319-1
KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). More...
| Schlagworte: | N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-benzenesulfonamide |
| Anwendung: | CaMKII inhibitor |
| CAS | 139298-40-1 |
| MW: | 501 D |
ab 108,00 €
KN-92 (hydrochloride) Artikelnummer: Cay9000890-1
KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII). At concentrations up to 25 µM, KN-92 is ineffective at inhibiting CaMKII or arresting cell growth of NIH 3T3 fibroblasts. It is intended to be used as a control compound in studies designed to...
| Schlagworte: | 2-[N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine, monohydrochloride |
| Anwendung: | CaMKII inhibitor |
| CAS | 1431698-47-3 |
| MW: | 493.4 D |
ab 108,00 €
KN-93 (water soluble) Artikelnummer: AG-CR1-0065-M001
Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor.
| Schlagworte: | KN-93 . H3PO4, 2-[N-(2-Hydroxyethyl)-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine . H3PO4 |
| Anwendung: | Ca2 dependent protein kinase II inhibitor |
| MW: | 501 D |
ab 50,00 €
KN-62 Artikelnummer: Cay13318-5
KN-62 is a selective, cell permeable inhibitor of Ca2+/calmodulin-dependent kinase type II (CaMKII, IC50 = 900 nM). It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM).
| Schlagworte: | 4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester,... |
| Anwendung: | CAMKII inhibitor |
| CAS | 127191-97-3 |
| MW: | 721.9 D |
ab 49,00 €
KN-93 (phosphate) Artikelnummer: Cay21472-1
KN-93 (phosphate) is a potent and selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII) (Ki = 370 nM), inhibiting both the alpha- and beta-subunits of CaMKII. It does not have significant effects on cAMP-dependent protein kinase, Ca2+/phospholipid-dependent protein kinase, myosin light chain kinase, or...
| Schlagworte: | N-[2-[[[(2E)-3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-benzenesulfonamide,... |
| Anwendung: | CaMKII inhibitor |
| CAS | 1188890-41-6 |
| MW: | 599 D |
ab 32,00 €
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Anti-phospho-CaM Kinase II (Thr286) Artikelnummer: 612-401-C71
Anti-CaM Kinase II pT286 Antibody is directed against CaM Kinase II protein phosphorylated at T286. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific...
| Schlagworte: | Anti-phospho-Camk2a, EC=2.7.11.17, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaM kinase II subunit alpha,... |
| Anwendung: | ELISA, WB |
| Reaktivität: | Rat |
501,00 €
Anti-phospho-CaMKII (Thr286) Artikelnummer: ARG52238.50
Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates...
| Schlagworte: | Anti-phospho-Camk2a, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaM kinase II subunit alpha,... |
| Anwendung: | WB |
| Reaktivität: | Rat |
498,00 €
Calmodulin-Dependent Protein Kinase II (290-309) Artikelnummer: Cay24318-500
Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC50 value of 52 nM and CaMKII-dependent phosphodiesterase activity (IC50 = 1.1...
| Schlagworte: | L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparaginyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysylglycyl-L-alanyl... |
| Anwendung: | CaMKII inhibitor, Calmodulin binding domain |
| CAS | 115044-69-4 |
| MW: | 2273.8 D |
118,00 €
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Human CAMK2A / CaMKII alpha protein CaM Kinase II alpha... Artikelnummer: G-HUFI02287.96
| Anwendung: | ELISA |
| Reaktivität: | Human |
629,00 €
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Anti-CaMKII, clone 6G9 Artikelnummer: 200-301-F00
Anti-CaMKII Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with CaMKII from mouse, rat, and bovine based on 100% homology with the immunizing sequence. Cross-reactivity with CaMKII from other sources has not been determined. Cell Signaling research. Protein...
| Schlagworte: | Anti-Camk2a, EC=2.7.11.17, Anti-CaMK-II subunit alpha, Anti-CaM kinase II subunit alpha, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | ELISA, IHC, IF, IP, WB |
| Reaktivität: | Mouse, Rat, Bovine |
506,00 €
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Anti-CaMKII, clone 22B1 Artikelnummer: 200-301-F01
Anti-CaMKII Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for CaMKII protein. A BLAST analysis was used to suggest cross-reactivity with CaMKII from rat based on 100% homology with the immunizing sequence. Cross-reactivity with CaMKII from other sources has not been...
| Schlagworte: | Anti-Camk2a, EC=2.7.11.17, Anti-CaMK-II subunit alpha, Anti-CaM kinase II subunit alpha, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | ELISA, IF, IP, WB |
| Reaktivität: | Rat |
506,00 €
+ Gratis T-Shirt
Anti-CaMKII (CaM Kinase II) Artikelnummer: 600-401-873
Protein function: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. [The...
| Schlagworte: | Anti-Camk2a, EC=2.7.11.17, Anti-CaMK-II subunit alpha, Anti-CaM kinase II subunit alpha, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | ELISA, WB |
| Reaktivität: | Human |
506,00 €