Anti-WNK1

Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ATA-HPA059157.25 25 µl -

7 - 10 Werktage*

300,00 €
ATA-HPA059157.100 100 µl -

7 - 10 Werktage*

421,00 €
 
Protein function: Serine/threonine kinase which plays an important role in the regulation of... mehr
Produktinformationen "Anti-WNK1"
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 71% and to rat: 70%
Schlagworte: Anti-p65, Anti-hWNK1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein, Anti-Protein kinase with no lysine 1, Anti-Protein kinase lysine-deficient 1, Anti-Serine/threonine-protein kinase WNK1
Hersteller: Atlas Antibodies
Hersteller-Nr: HPA059157

Eigenschaften

Anwendung: IHC
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PPFPAPSLTQ SQQPLEDLDA QLRRTLSPEM ITVTSAVGPV SMAAPTAITE AGTQPQKGVS QVKEGPVLAT SSGAGVFKMG RFQVSVAADG A (ATA-APrEST78010)

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +20°C (International: +20°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
Hier kriegen Sie ein Zertifikat
oder , um Analysenzertifikate anzufordern.
Bewertungen lesen, schreiben und diskutieren... mehr
Kundenbewertungen für "Anti-WNK1"
Bewertung schreiben
oder , um eine Produktbewertung abzugeben.
Zuletzt angesehen