Zu "K08867" wurden 95 Artikel gefunden!
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WNK463
Artikelnummer: Cay37673-10
WNK463 is an inhibitor of WNK lysine-deficient protein kinase 1 (WNK1), WNK2, WNK3, and WNK4 (IC50s = 5, 1, 6, and 9 nM, respectively). It is selective for WNK1-4 over a panel of 442 kinases at 10 µM. In vivo, WNK463 (1, 3, and 10 mg/kg) decreases blood pressure, as well as increases urine output and urinary sodium...
| Schlagworte: | N-(1,1-dimethylethyl)-1-[1-[5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]-4-piperidinyl]-1H-imidazole-5-carbox... |
| Anwendung: | WNK1-4 inhibitor |
| CAS | 2012607-27-9 |
| MW: | 463.5 D |
ab 106,00 €
WNK-IN-11
Artikelnummer: Cay29676-5
WNK-IN-11 is an allosteric inhibitor of lysine-deficient protein kinase 1 (WNK1, IC50 = 4 nM). It is 57- and 1000-fold selective for WNK1 over WNK2 and WNK4, respectively, as well as a panel of 400 kinases at 10 µM. It inhibits WNK1-mediated phosphorylation of the transcription factor OSR1 in HEK293 cells (EC50 =...
| Schlagworte: | [5-chloro-2-[2-(methylamino)-4-thiazolyl]-4-pyridinyl][4-[(4-chlorophenyl)methyl]-1-piperazinyl]-methanone |
| Anwendung: | Allosteric WNK1 inhibitor |
| CAS | 2123489-30-3 |
| MW: | 462.4 D |
ab 66,00 €
Anti-WNK1
Artikelnummer: A301-514A
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A,...
| Schlagworte: | Anti-p65, Anti-hWNK1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein, Anti-Protein kinase with no lysine... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-WNK1
Artikelnummer: ATA-HPA059157.25
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A,...
| Schlagworte: | Anti-p65, Anti-hWNK1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein, Anti-Protein kinase with no lysine... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Anti-WNK1
Artikelnummer: A301-515A
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A,...
| Schlagworte: | Anti-p65, Anti-hWNK1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein, Anti-Protein kinase with no lysine... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-WNK3
Artikelnummer: A301-877A
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively (PubMed:16275913,...
| Schlagworte: | Anti-WNK3, Anti-KIAA1566, EC=2.7.11.1, Anti-Protein kinase with no lysine 3, Anti-Protein kinase lysine-deficient 3,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-WNK1
Artikelnummer: NSJ-R32386
0.5mg/ml if reconstituted with 0.2ml sterile DI water. WNK lysine deficient protein kinase 1, also known as WNK1, is an enzyme that in humans is encoded by the WNK1 gene. The human gene is located on short arm of chromosome 12 (12p13.3). This gene encodes a member of the WNK subfamily of serine/threonine protein...
| Schlagworte: | Anti-p65, Anti-HSN2, Anti-WNK1, Anti-hWNK1, EC=2.7.11.1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-WNK1
Artikelnummer: E-AB-60739.120
This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory...
| Schlagworte: | Anti-p65, Anti-hWNK1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein, Anti-Protein kinase with no lysine... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 198,00 €
Anti-WNK1
Artikelnummer: ARG59406.100
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A,...
| Schlagworte: | Anti-p65, Anti-hWNK1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein, Anti-Protein kinase with no lysine... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-WNK1
Artikelnummer: ARG59467.50
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A,...
| Schlagworte: | Anti-p65, Anti-hWNK1, Anti-Kinase deficient protein, Anti-Erythrocyte 65 kDa protein, Anti-Protein kinase with no lysine... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
520,00 €
Anti-phospho-WNK1 (Thr60)
Artikelnummer: ARG66415.100
Protein function: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A,...
| Schlagworte: | Anti-phospho-p65, Anti-phospho-hWNK1, Anti-phospho-Kinase deficient protein, Anti-phospho-Erythrocyte 65 kDa protein,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
Anti-WNK4
Artikelnummer: E-AB-19365.120
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and...
| Schlagworte: | Anti-Protein kinase with no lysine 4, Anti-Protein kinase lysine-deficient 4, Anti-Serine/threonine-protein kinase WNK4,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €