Anti-GR

Nr3c1 (nuclear receptor subfamily 3 group C member 1) is also known as the glucocorticoid receptor (GR) and functions as both a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Alternative names for the Nr3c1 include GR, and GRL. [taken from NCBI Entrez Gene (Gene ID: 2908)]