Zu "K05771" wurden 289 Artikel gefunden!
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Dexamethasone
Artikelnummer: Cay11015-500
Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively). Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in...
| Schlagworte: | MK-125, NSC 34521, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione |
| Anwendung: | Synthetic glucocorticoid |
| CAS | 50-02-2 |
| MW: | 392.5 D |
ab 78,00 €
Halobetasol
Artikelnummer: TGM-T78512-50mg
Description: Halobetasol (Ulobetasol), a corticosteroid, is utilized in the research of severe localized psoriasis [1]. Target: Others. Smiles: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CCl)=O)(O)[C@@H](C)C3)[H])(C[C@H](F)C=4[C@]2(C)C=CC(=O)C4)[H]
| Schlagworte: | Ulobetasol |
| Anwendung: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 98651-66-2 |
| MW: | 428.9 D |
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Prednisone acetate
Artikelnummer: TGM-T8396-1g
Description: Prednisone acetate (Prednisone 21-acetate) is a glucocorticoid receptor agonist with immunomodulating properties and anti-inflammatory. Target: Glucocorticoid Receptor. Smiles: [H][C@@]12CC[C@](O)(C(=O)COC(C)=O)[C@@]1(C)CC(=O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C. References: Williams J R , Moore...
| Schlagworte: | Prednisone 21-acetate |
| Anwendung: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 125-10-0 |
| MW: | 400.46 D |
ab 42,00 €
Fluprednisolone
Artikelnummer: TGM-T9047-100mg
Description: Fluprednisolone (NSC-47439) is a synthetic glucocorticoid that has anti-inflammatory properties. Target: Others. Smiles: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]. References: Cho SH, Park JA, Zheng W, Abd El-Aty AM, Kim SK, Choi JM, Yi H,...
| Schlagworte: | NSC47439, NSC-47439, NSC 47439 |
| Anwendung: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 53-34-9 |
| MW: | 378.43 D |
ab 45,00 €
11-Deoxycortisol-2,2,4,6,6-d5
Artikelnummer: TGM-TMID-0111-1mg
Description: 11-Deoxycortisol-2,2,4,6,6-d5 is a deuterated compound of 11-Deoxycortisol. 11-Deoxycortisol has a CAS number of 152-58-9. Cortodoxone is a glucocorticoid steroid hormone that is an intermediate in the biosynthesis of cortisol in the adrenal gland. Smiles:...
| Anwendung: | Glucocorticoid receptor agonist, LC/MS internal standard |
| CAS | 1258063-56-7 |
| MW: | 351.49 D |
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Budesonide-d8
Artikelnummer: TGM-TMID-0006-1mg
Description: Budesonide-d8 is a deuterated compound of Budesonide. Budesonide has a CAS number of 51333-22-3. Budesonide, an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects...
| Schlagworte: | mixture of diastereomers-d8 |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, glucocorticoid receptor agonist |
| CAS | 1105542-94-6 |
| MW: | 438.58 D |
ab 275,00 €
Hydrocortisone-d4
Artikelnummer: TGM-TMIJ-0193-1mg
Description: Hydrocortisone-d4 is a deuterated compound of Hydrocortisone. Hydrocortisone has a CAS number of 50-23-7. Hydrocortisone, a glucocorticoid receptor agonist, promotes protein catabolism, gluconeogenesis, capillary wall stability, renal excretion of calcium, and suppresses immune and inflammatory...
| Anwendung: | GC-MS, LC-MS, quantification, internal standard, glucocorticoid receptor agonist |
| CAS | 73565-87-4 |
| MW: | 366.48 D |
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NR3C1 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPY-06836-100ug
Description: NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription,...
| Schlagworte: | GCR, GCCR, GCRST, nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), GR, GRL |
| MW: | 10.95 kD |
699,00 €
Velsecorat
Artikelnummer: TGM-TQ0225-100mg
Description: Velsecorat (AZD7594) is an effective and selective nonsteroidal glucocorticoid receptor modulator (IC50: 0.9 nM). Target: Glucocorticoid Receptor. Smiles: C[C@H](NC(=O)C(C)(F)F)[C@H](Oc1ccc2n(ncc2c1)-c1cccc(c1)C(=O)N[C@@H]1CCOC1)c1ccc2OCCOc2c1. References: Hemmerling M, et al. Selective Nonsteroidal...
| Schlagworte: | AZ13189620, AZD7594 |
| Anwendung: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 1196509-60-0 |
| MW: | 606.62 D |
ab 55,00 €
Flurandrenolide
Artikelnummer: TGM-TQ0246-2mg
Description: Fludroxycortide, a synthetic topical steroid, serves as an anti-inflammatory treatment for skin irritations. Target: Others. Smiles: [H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@@]4([H])[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)CO
| Schlagworte: | Flurandrenolone, Fludroxycortide |
| Anwendung: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 1524-88-5 |
| MW: | 436.51 D |
83,00 €
Cloprednol
Artikelnummer: TGM-T25264-100mg
Description: Cloprednol is a synthetic glucocorticoid. It has an anti-inflammatory potency twice that of prednisone. Target: Others. Smiles: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(C(Cl)=C3)=CC(=O)C=C4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(CO)=O)O)[H]. References: Medici TC, Rüegsegger P. Does alternate-day cloprednol therapy...
| Schlagworte: | Syntestan, RS 4691, RS-4691, Cloradryn, Novacort |
| Anwendung: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 5251-34-3 |
| MW: | 392.87 D |
ab 1.520,00 €
Cortivazol
Artikelnummer: TGM-T25271-100mg
Description: Cortivazol is an Anti-Inflammatory Drug. Target: Others. Smiles: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(C(C)=C3)=CC5=C(C4)C=NN5C6=CC=CC=C6)([C@@H](O)C1)[H])[H])(C[C@@H](C)[C@@]2(C(COC(C)=O)=O)O)[H]. References: Thompson EB, Srivastava D, Johnson BH. Interactions of the phenylpyrazolo steroid cortivazol with...
| Schlagworte: | Dilaster |
| Anwendung: | Targets glucocorticoid receptor (NR3C1, GR) |
| CAS | 1110-40-3 |
| MW: | 530.65 D |
ab 3.624,00 €