Zu "K05771" wurden 308 Artikel gefunden!
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Anti-Recombinant Glucocorticoid Receptor, clone 12B8
Artikelnummer: E-AN301002L.100
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the...
| Schlagworte: | Anti-NR3C1, Anti-Glucocorticoid receptor, Anti-Nuclear receptor subfamily 3 group C member 1, Recombinant Glucocorticoid... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Zebrafish Glucocorticoid receptor / Gr / Nr3c1
Artikelnummer: NSJ-RZ1226
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glucocorticoid receptor (Gr), also known as nuclear receptor subfamily three group C member one (Nr3c1), is a ligand activated transcription factor that mediates the effects of glucocorticoid hormones such as cortisol. In zebrafish, the glucocorticoid receptor...
| Schlagworte: | Anti-gr, Anti-utut, Anti-nr3c1, Anti-utouto, Anti-fb13f09, Anti-wu:fb13f09, Anti-zgc:113038, Anti-Glucocorticoid receptor,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Dexamethasone
Artikelnummer: Cay11015-500
Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively). Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in...
| Schlagworte: | MK-125, NSC 34521, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione |
| Anwendung: | Synthetic glucocorticoid |
| CAS | 50-02-2 |
| MW: | 392.5 D |
ab 91,00 €
Hydrocortisone
Artikelnummer: Cay20739-1
Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor, with an approximately 6- to 10-fold greater affinity for MR....
| Schlagworte: | Cortisol, Dihydrocostisone, NSC 10483, (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione |
| Anwendung: | Natural glucocorticoid |
| CAS | 50-23-7 |
| MW: | 362.5 D |
ab 47,00 €
Hydrocortisone 21-hemisuccinate (sodium salt)
Artikelnummer: Cay18226-100
Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6). It is commonly used to...
| Schlagworte: | Cortisol 21-hemisuccinate, Hydrocortisone sodium succinate, ST51037292, U-4905,... |
| Anwendung: | Water-soluble cortisol derivative, GR ligand, pluripotent stem cell differentiation |
| CAS | 125-04-2 |
| MW: | 484.5 D |
ab 55,00 €
Dexamethasone-d4
Artikelnummer: Cay22100-1
Dexamethasone-d4 is intended for use as an internal standard for the quantification of dexamethasone (Cay-11015) by GC- or LC-MS. Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively)....
| Schlagworte: | 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione-4,6,21,21-d4 |
| Anwendung: | GC-MS, LC-MS, internal standard, Glucocorticoid receptor agonist |
| CAS | 2483831-63-4 |
| MW: | 396.5 D |
ab 105,00 €
Budesonide
Artikelnummer: Cay15407-50
Budesonide is a glucocorticoid and an agonist of glucocorticoid receptors (EC50 = 45.7 pM in a transactivation assay). It is selective for glucocorticoid over mineralocorticoid receptors (EC50 = 7,620 pM). Budesonide inhibits LPS-induced TNF-alpha release from human peripheral blood mononuclear cells (PBMCs, IC50 =...
| Schlagworte: | 16alpha,17-[butylidenebis(oxy)]-11beta,21-dihydroxy-pregna-1,4-diene-3,20-dione |
| Anwendung: | Glucocorticoid receptor agonist |
| CAS | 51333-22-3 |
| MW: | 430.5 D |
ab 69,00 €
Betamethasone-d5
Artikelnummer: Cay39560-1
| Schlagworte: | beta-Methasone-d5, 9-fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione-4,6,11,12,12-d5 |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, glucocorticoid receptor agonist |
| CAS | 2244574-92-1 |
| MW: | 397.491363 D |
1.002,00 €
Triamcinolone acetonide
Artikelnummer: Cay18026-100
Triamcinolone acetonide is a synthetic corticosteroid. It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow...
| Schlagworte: | NSC 21916, 9-fluoro-11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione |
| Anwendung: | Glucocorticoid receptor agonist |
| CAS | 76-25-5 |
| MW: | 434.5 D |
ab 51,00 €
Prednisolone
Artikelnummer: Cay20866-1
Prednisolone is a glucocorticoid and mineralocorticoid receptor agonist and an active metabolite of the prodrugs and synthetic glucocorticoids prednisolone phosphate (Cay-15933) and prednisone (Cay-20677). It selectively binds to the glucocorticoid and mineralocorticoid receptors over the progesterone, androgen, and...
| Schlagworte: | NSC 9120, NSC 9900, 11beta,17,21-trihydroxy-pregna-1,4-diene-3,20-dione |
| Anwendung: | Glucocorticoid receptor agonist |
| CAS | 50-24-8 |
| MW: | 360.4 D |
ab 51,00 €
Hydrocortisone-d4
Artikelnummer: Cay26500-500
Hydrocortisone-d4 is intended for use as an internal standard for the quantification of hydrocortisone/cortisol (Cay-20739) by GC- or LC-MS. Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an...
| Schlagworte: | Cortisol-d4, (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione-9,11,12,12-d4 |
| Anwendung: | GC-MS, LC-MS, quantification, internal standard, glucocorticoid receptor agonist |
| CAS | 73565-87-4 |
| MW: | 366.5 D |
ab 144,00 €
Ursodeoxycholic acid
Artikelnummer: AG-CN2-0411-G001
White to off-white powder. Soluble in DMSO, ethanol or dimethylformamide. Sparingly soluble in water. Endogenous hydrophilic bile acid, Antioxidant. Cytoprotective against oxidative stress and cell death, Hepatoprotective at cellular and molecular level, including stabilization of membranes. Protects hepatocytes...
| Schlagworte: | UDCA, USAN, BRN 3219888, NSC 657950, NSC 683769 |
| Anwendung: | Antioxidant, Glucocorticoid Receptor (GR) agonist, ADAM17 inhibitor |
| CAS | 128-13-2 |
| MW: | 392,6 D |
ab 44,00 €