Zu "K05771" wurden 301 Artikel gefunden!
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Anti-Recombinant Glucocorticoid Receptor, clone 12B8
Artikelnummer: E-AN301002L.100
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the...
| Schlagworte: | Anti-NR3C1, Anti-Glucocorticoid receptor, Anti-Nuclear receptor subfamily 3 group C member 1, Recombinant Glucocorticoid... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Zebrafish Glucocorticoid receptor / Gr / Nr3c1
Artikelnummer: NSJ-RZ1226
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glucocorticoid receptor (Gr), also known as nuclear receptor subfamily three group C member one (Nr3c1), is a ligand activated transcription factor that mediates the effects of glucocorticoid hormones such as cortisol. In zebrafish, the glucocorticoid receptor...
| Schlagworte: | Anti-gr, Anti-utut, Anti-nr3c1, Anti-utouto, Anti-fb13f09, Anti-wu:fb13f09, Anti-zgc:113038, Anti-Glucocorticoid receptor,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Dexamethasone
Artikelnummer: Cay11015-500
Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively). Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in...
| Schlagworte: | MK-125, NSC 34521, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione |
| Anwendung: | Synthetic glucocorticoid |
| CAS | 50-02-2 |
| MW: | 392.5 D |
ab 88,00 €
Hydrocortisone
Artikelnummer: Cay20739-1
Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor, with an approximately 6- to 10-fold greater affinity for MR....
| Schlagworte: | Cortisol, Dihydrocostisone, NSC 10483, (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione |
| Anwendung: | Natural glucocorticoid |
| CAS | 50-23-7 |
| MW: | 362.5 D |
ab 45,00 €
Betamethasone-d5
Artikelnummer: Cay39560-1
| Schlagworte: | beta-Methasone-d5, 9-fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione-4,6,11,12,12-d5 |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, glucocorticoid receptor agonist |
| CAS | 2244574-92-1 |
| MW: | 397.491363 D |
972,00 €
Hydrocortisone 21-hemisuccinate (sodium salt)
Artikelnummer: Cay18226-100
Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6). It is commonly used to...
| Schlagworte: | Cortisol 21-hemisuccinate, Hydrocortisone sodium succinate, ST51037292, U-4905,... |
| Anwendung: | Water-soluble cortisol derivative, GR ligand, pluripotent stem cell differentiation |
| CAS | 125-04-2 |
| MW: | 484.5 D |
ab 53,00 €
Dexamethasone-d4
Artikelnummer: Cay22100-1
Dexamethasone-d4 is intended for use as an internal standard for the quantification of dexamethasone (Cay-11015) by GC- or LC-MS. Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively)....
| Schlagworte: | 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione-4,6,21,21-d4 |
| Anwendung: | GC-MS, LC-MS, internal standard, Glucocorticoid receptor agonist |
| CAS | 2483831-63-4 |
| MW: | 396.5 D |
ab 102,00 €
Budesonide
Artikelnummer: Cay15407-50
Budesonide is a glucocorticoid and an agonist of glucocorticoid receptors (EC50 = 45.7 pM in a transactivation assay). It is selective for glucocorticoid over mineralocorticoid receptors (EC50 = 7,620 pM). Budesonide inhibits LPS-induced TNF-alpha release from human peripheral blood mononuclear cells (PBMCs, IC50 =...
| Schlagworte: | 16alpha,17-[butylidenebis(oxy)]-11beta,21-dihydroxy-pregna-1,4-diene-3,20-dione |
| Anwendung: | Glucocorticoid receptor agonist |
| CAS | 51333-22-3 |
| MW: | 430.5 D |
ab 67,00 €
21-deacetoxy Deflazacort
Artikelnummer: Cay43019-10
21-deacetoxy Deflazacort is a glucocorticoid. It induces hepatic gluconeogenesis in adrenalectomized rats when administered at a dose of 0. mg/kg.. Solulibility: DMSO: Sparingly soluble: 1-10 mg/ml: Ethanol: Slightly soluble: 0.1-1 mg/ml.
| Schlagworte: | 11beta-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16beta-d]oxazole-3,20-dione |
| Anwendung: | Glucocorticoid |
| CAS | 13649-88-2 |
| MW: | 383.49 D |
ab 188,00 €
Triamcinolone hexacetonide
Artikelnummer: Cay42600-100
Triamcinolone hexacetonide is a synthetic corticosteroid and prodrug form of triamcinolone acetonide (Cay-18026). Intra-articular administration of triamcinolone hexacetonide decreases joint swelling in a rabbit model of adjuvant-induced arthritis. Formulations containing triamcinolone hexacetonide have been used in...
| Schlagworte: | 21-(3,3-dimethyl-1-oxobutoxy)-9-fluoro-11beta-hydroxy-16a,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione |
| Anwendung: | Triamcinolone acetonide prodrug, synthetic corticosteroid, glucocorticoid receptor agonist |
| CAS | 5611-51-8 |
| MW: | 532.64 D |
ab 118,00 €
Triamcinolone acetonide
Artikelnummer: Cay18026-100
Triamcinolone acetonide is a synthetic corticosteroid. It decreases cytokine levels, the firing rate of sensory neurons, and mechanical hypersensitivity in a rat spinal nerve ligation model when used at a dose of 1.5 mg/kg prior to and following surgery for three days. Triamcinolone acetonide also decreases outflow...
| Schlagworte: | NSC 21916, 9-fluoro-11beta,21-dihydroxy-16alpha,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione |
| Anwendung: | Glucocorticoid receptor agonist |
| CAS | 76-25-5 |
| MW: | 434.5 D |
ab 49,00 €
Prednisolone
Artikelnummer: Cay20866-1
Prednisolone is a glucocorticoid and mineralocorticoid receptor agonist and an active metabolite of the prodrugs and synthetic glucocorticoids prednisolone phosphate (Cay-15933) and prednisone (Cay-20677). It selectively binds to the glucocorticoid and mineralocorticoid receptors over the progesterone, androgen, and...
| Schlagworte: | NSC 9120, NSC 9900, 11beta,17,21-trihydroxy-pregna-1,4-diene-3,20-dione |
| Anwendung: | Glucocorticoid receptor agonist |
| CAS | 50-24-8 |
| MW: | 360.4 D |
ab 49,00 €