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Prednisolone-d7
Prednisolone-d7

Artikelnummer: Cay35162-1

Prednisolone-d7 is intended for use as an internal standard for the quantification of prednisolone (Cay-20866) by GC- or LC-MS. Prednisolone is a glucocorticoid and mineralocorticoid receptor agonist and an active metabolite of the prodrugs and synthetic glucocorticoids prednisolone phosphate (Cay-15933) and...
Schlagworte: 11beta,17,21-trihydroxy-pregna-1,4-diene-3,20-dione-2,4,6,9,11,12,12-d7
Anwendung: GC-MS, LC-MS internal standard, quantification, glucocorticoid receptor agonist
MW: 367.5 D
ab 267,00 €
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-10 %
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Human NR3C1 (Nuclear Receptor Subfamily 3, Group C, Member 1) ELISA Kit
Human NR3C1 (Nuclear Receptor Subfamily 3, Group C,...

Artikelnummer: ELK-ELK4031.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human NR3C1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human NR3C1. Next,...
Schlagworte: GR, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
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-10 %
Rabattaktion
Rat NR3C1 (Nuclear Receptor Subfamily 3, Group C, Member 1) ELISA Kit
Rat NR3C1 (Nuclear Receptor Subfamily 3, Group C, Member...

Artikelnummer: ELK-ELK5622.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NR3C1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NR3C1. Next,...
Schlagworte: GR, Grl, Nr3c1, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1
Anwendung: ELISA
Spezies-Reaktivität: rat
365,00 € ab 328,50 €
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-10 %
Rabattaktion
Anti-Glucocorticoid receptor
Anti-Glucocorticoid receptor

Artikelnummer: ELK-EA026.50

The glucocorticoid receptor (GR or GCR).The GR is expressed in almost every cell in the body and regulates genes controlling the development, metabolism, and immune response. Because the receptor gene is expressed in several forms, it has many different (pleiotropic) effects in different parts of the body. Protein...
Schlagworte: Anti-GR, Anti-GRL, Anti-Glucocorticoid receptor, Anti-Nuclear receptor subfamily 3 group C member 1, Glucocorticoid...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
169,00 € 152,10 €
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Betamethasone-d5
Betamethasone-d5

Artikelnummer: Cay39560-5

Betamethasone-d5 is intended for use as an internal standard for the quantification of betamethasone (Cay-20363) by GC- or LC-MS. Betamethasone is a synthetic corticosteroid. In vivo, betamethasone (5 mg/kg) reduces bronchoalveolar lavage fluid (BALF) matrix metalloproteinase-2 (MMP-2) and MMP-9 activities,...
Schlagworte: beta-Methasone-d5, 9-fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione-4,6,11,12,12-d5
Anwendung: GC-MS, LC-MS, internal standard, quantification, glucocorticoid receptor agonist
CAS 2244574-92-1
MW: 397.5 D
2.046,00 €
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Dexamethasone
Dexamethasone

Artikelnummer: Cay11015-500

Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively). Through receptor activation, dexamethasone has both transactivating and transrepressing effects on gene expression, producing, in...
Schlagworte: MK-125, NSC 34521, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione
Anwendung: Synthetic glucocorticoid
CAS 50-02-2
MW: 392.5 D
ab 77,00 €
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Beclomethasone Dipropionate
Beclomethasone Dipropionate

Artikelnummer: Cay38880-250

Beclomethasone dipropionate is a glucocorticoid receptor agonist and prodrug form of beclomethasone 17-propionate (Cay-38884). Beclomethasone dipropionate is converted to beclomethasone 17-propionate or beclomethasone 21-propionate via esterases, which are subsequently hydrolyzed to beclomethasone (Cay-33196). It...
Schlagworte: BC-DP, BDP, Beclomethasone 17,21-dipropionate,...
Anwendung: Beclomethasone 17-propionate prodrug, glucocorticoid receptor agonist
CAS 5534-09-8
MW: 521 D
ab 96,00 €
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Beclomethasone 17-Propionate
Beclomethasone 17-Propionate

Artikelnummer: Cay38884-1

Beclomethasone 17-propionate is a glucocorticoid receptor agonist and an active metabolite of the glucocorticoid prodrug beclomethasone dipropionate (Cay-38880). It is formed from beclomethasone dipropionate via esterases and is subsequently hydrolyzed to beclomethasone (Cay-33196). Beclomethasone 17-propionate...
Schlagworte: 17-BMP, Beclometasone 17-Propionate, Beclomethasone 17-Monopropionate,...
Anwendung: Beclomethasone dipropionate active metabolite, glucocorticoid receptor agonist
CAS 5534-18-9
MW: 465 D
ab 159,00 €
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Dexamethasone Lipodisq Sterile Solution
Dexamethasone Lipodisq Sterile Solution

Artikelnummer: IAX-700-107-L001

Dexamethasone Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Dexamethasone, developed in 1957 and granted FDA approval in 1958, is a corticosteroid structurally similar to hydrocortisone and prednisolone. Dexamethasone is used to treat conditions including: endocrine, rheumatic,...
Schlagworte: MK-125, NSC 34521, 9alpha-Fluoro-16alpha-methylprednisolone,...
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 50-02-2
MW: 392,5 D
286,00 €
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Hydrocortisone 21-hemisuccinate (sodium salt)
Hydrocortisone 21-hemisuccinate (sodium salt)

Artikelnummer: Cay18226-100

Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6). It is commonly used to...
Schlagworte: Cortisol 21-hemisuccinate, Hydrocortisone sodium succinate, ST51037292, U-4905,...
Anwendung: Water-soluble cortisol derivative, GR ligand, pluripotent stem cell differentiation
CAS 125-04-2
MW: 484.5 D
ab 40,00 €
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Hydrocortisone
Hydrocortisone

Artikelnummer: Cay20739-1

Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor, with an approximately 6- to 10-fold greater affinity for MR....
Schlagworte: Cortisol, Dihydrocostisone, NSC 10483, (11beta)-11,17,21-trihydroxy-pregn-4-ene-3,20-dione
Anwendung: Natural glucocorticoid
CAS 50-23-7
MW: 362.5 D
ab 38,00 €
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Dexamethasone-d4
Dexamethasone-d4

Artikelnummer: Cay22100-1

Dexamethasone-d4 is intended for use as an internal standard for the quantification of dexamethasone (Cay-11015) by GC- or LC-MS. Dexamethasone is a synthetic glucocorticoid that binds the human glucocorticoid receptor with a higher affinity than a natural ligand, cortisol (Kd = 5 nM versus 17 nM, respectively)....
Schlagworte: 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione-4,6,21,21-d4
Anwendung: GC-MS, LC-MS, Internal standard, Glucocorticoid receptor agonist
CAS 2483831-63-4
MW: 396.5 D
ab 92,00 €
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