Anti-Galectin-8 (human), Unconjugated Clone B-Z18

Anti-Galectin-8 (human), Unconjugated Clone B-Z18
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
DC-857.013.020 200 tests (2 ml) -

3 - 8 Werktage*

157,00 €
Specificity: Recognizes both natural and recombinant human galectin-8, Format: Phosphate-buffered... mehr
Produktinformationen "Anti-Galectin-8 (human), Unconjugated Clone B-Z18"
Specificity: Recognizes both natural and recombinant human galectin-8, Format: Phosphate-buffered saline with 1% BSA and 0.09% sodium azide, Working Dilution: Use 10 µl to label 106 cells or 100 µl of whole blood, Storage: Stable at +2-8°C for 12 months. DO NOT FREEZE. Protein function: Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878). Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane, these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878). Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878). Required to restrict infection of bacterial invasion such as S.typhimurium (PubMed:22246324). Also required to restrict infection of Picornaviridae viruses (PubMed:28077878). Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans (PubMed:21288902). [The UniProt Consortium]
Schlagworte: Anti-Gal-8, Anti-PCTA-1, Anti-Po66-CBP, Anti-Galectin-8, Anti-Po66 carbohydrate-binding protein, Anti-Prostate carcinoma tumor antigen 1, Anti-Human Galectin-8 Monoclonal Antibody, Unconjugated Clone B-Z18
Hersteller: Diaclone
Hersteller-Nr: 857.013


Anwendung: FC
Antikörper-Typ: Monoclonal
Klon: B-Z18
Konjugat: No
Wirt: Mouse
Reaktivität: Human
Immunogen: Recombinant human galectin-8

Handhabung & Sicherheit

Lagerung: +4°C (do not freeze)
Versand: +20°C (International: °C)
Signalwort: Danger
H-Sätze: H300, H310, H410, EUH032
P-Sätze: P262, P264, P270, P273, P280, P321, P330, P391, P301+P310, P302+P352, P361+P364, P405, P501
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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