Anti-FP Receptor

The prostaglandin F2alpha receptor (FP receptor) is a G protein-coupled receptor known to elicit smooth muscle contraction in a variety of tissues. FP receptor mRNA is found in reproductive, gastric, neural, and ocular tissues as well as specialized cells of the kidney. Two FP receptor isoforms, FPA and FPB have been identified in sheep. FPB receptor is truncated at the carboxy-terminus thereby preventing desensitization (which normally occurs by protein kinase C phosphorylation of FPA) and produces aberrant signalling in FPB transfectants. The existence of a truncated human FP isoform responsible for signal-amplification contributing to luteolysis, cell growth, or malignant transformation is currently unknown. Cayman's FP Receptor Polyclonal Antibody can be used for Western blot applications. The calculated size of FP Receptor is 41 kDa and this antibody recognizes multiple bands from 50-67 kDa from human, bovine, mouse, ovine, and rat samples.Synonyms: PGF2alpha Receptor, Prostaglandin F2alpha Receptor. Immunogen: Synthetic peptide from the N-terminal cytoplasmic region of mouse protein FP receptor. Formulation: (Request formulation change), Peptide-affinity purified antibody lyophilized from 500 µl. Storage Buffer: TBS, pH 7.4, with 0.5% BSA when reconstituted in 500 µl deionized water. Host: Rabbit. Isotype: IgG. Applications: WB. UniProt Accession #: P43117. Origin: Animal/Rabbit.