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Zu "K04262" wurden 27 Artikel gefunden!
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Artikelnummer: Cay10005440-25
Tafluprost is a prodrug form of the FP receptor agonist tafluprost (free acid) (Cay-10005439) and a derivative of prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It decreases pupillary diameter in cats when applied topically at doses of 0.0001 or 0.001% v/v. Ocular administration of tafluprost (0.0005% v/v)...
Schlagworte: | AFP-168, 15,15-difluoro-9alpha,11alpha-dihydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oic acid, isopropyl... |
Anwendung: | FP receptor agonist |
CAS | 209860-87-7 |
MW: | 452.5 D |
ab 150,00 €
Artikelnummer: Cay39027-1
AMX12006 is an antagonist of the prostaglandin E2 (PGE2) receptor subtype EP4 (IC50 = 4.3 nM). It is selective for EP4 over EP1, EP2, and EP3 receptors (IC50s = >10 µM for all). AMX12006 is cytotoxic to MCF-7 and 4T1 breast and CT26 colon cancer cells (IC50s = 46.73, 79.47, and 41.39 µM, respectively). It reduces...
Schlagworte: | 4-[(1S)-1-[[[1-methyl-3-[[3-(trifluoromethyl)phenyl]amino]-1H-indol-2-yl]carbonyl]amino]ethyl]-benzoic acid |
Anwendung: | EP4 receptor (prostaglandin E receptor 4) antagonist |
CAS | 2639775-01-0 |
MW: | 481.5 D |
ab 77,00 €
Artikelnummer: Cay101802-1
The prostaglandin F2alpha receptor (FP receptor) is a G protein-coupled receptor known to elicit smooth muscle contraction in a variety of tissues. FP receptor mRNA is found in reproductive, gastric, neural, and ocular tissues as well as specialized cells of the kidney. Two FP receptor isoforms, FPA and FPB have...
Schlagworte: | Anti-Ptgfr, Anti-PGF receptor, Anti-PGF receptor, Anti-PGF2-alpha receptor, Anti-PGF2-alpha receptor, Anti-Prostanoid FP... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | murine, rat, human, bovine, ovine |
422,00 €
Artikelnummer: Cay9000349-1
9-keto Tafluprost is a derivative of the FP receptor agonist tafluprost (Cay-10005440).Formal Name: 7-[(1R,2R,3R)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3-hydroxy-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester. CAS Number: 261179-75-3. Molecular Formula: C25H32F2O5. Formula Weight: 450.5. Purity:...
Schlagworte: | 7-[(1R,2R,3R)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3-hydroxy-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester |
Anwendung: | Tafluprost (FP receptor agonist) derivative |
CAS | 261179-75-3 |
MW: | 450.5 D |
ab 159,00 €
Artikelnummer: Cay9000350-1
9-keto Latanoprost is a derivative of the FP receptor agonist latanoprost (Cay-16812).Formal Name: (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester. CAS Number: 141074-06-8. Molecular Formula: C26H38O5. Formula Weight: 430.6. Purity: >98%....
Schlagworte: | (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester |
Anwendung: | Latanoprost (FP receptor agonist) derivative |
CAS | 141074-06-8 |
MW: | 430.6 D |
ab 96,00 €
Artikelnummer: Cay10010351-1
17-phenyl trinor Prostaglandin F2alpha (17-phenyl trinor PGF2alpha) is a metabolically stable analog of PGF2alpha and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2alpha. The ethyl amide of 17-phenyl trinor PGF2alpha bimatoprost has been approved for use as...
Schlagworte: | 17-phenyl trinor PGF2alpha methyl amide, Bimatoprost methyl amide, Methylamido Dihydro Noralfaprostal,... |
Anwendung: | FP receptor agonist |
CAS | 155206-01-2 |
MW: | 401.5 D |
ab 77,00 €
Artikelnummer: Cay16810-1
17-phenyl trinor Prostaglandin F2alpha (17-phenyl trinor PGF2alpha) is a metabolically stable analog of PGF2alpha and is a potent agonist for the FP receptor. It binds to the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2alpha. At the rat recombinant FP receptor expressed...
Schlagworte: | 17-phenyl trinor PGF2alpha, Bimatoprost (free acid),... |
Anwendung: | FP receptor agonist |
CAS | 38344-08-0 |
MW: | 388.5 D |
ab 77,00 €
Artikelnummer: Cay10008370-1
AL 8810 is an 11beta-fluoro analog of prostaglandin F2alpha (PGF2alpha) which acts as a potent and selective antagonist at the FP receptor. AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as latanoprost...
Schlagworte: | 9alpha,15R-dihydroxy-11beta-fluoro-15-(2,3-dihydro-1H-inden-2-yl)-16,17,18,19,20-pentanor-prosta-5Z,13E-dien-1-oic acid,... |
Anwendung: | FP receptor antagonist |
CAS | 1176541-11-9 |
MW: | 416.5 D |
ab 96,00 €
Artikelnummer: Cay10010978-100
Latanoprost is the isopropyl ester of 17-phenyl-13,14-dihydro prostaglandin F2alpha. It is a prodrug of the free acid, which is a potent agonist of the FP receptor in the eye. Isopropyl 5-(diphenylphosphoryl)pentanoate is a potential trace impurity in commercial preparations of latanoprost.Formal Name:...
Schlagworte: | DPP isopropyl ester, 5-diphenylphosphoryl pentanoic isopropyl ester |
Anwendung: | FP receptor agonist |
CAS | 2088449-88-9 |
MW: | 344.4 D |
ab 43,00 €
Artikelnummer: ARG56485.250
Protein function: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum. Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling...
Schlagworte: | Anti-PTGFR, Anti-PGF receptor, Anti-PGF2-alpha receptor, Anti-Prostanoid FP receptor, Anti-Prostaglandin F2-alpha receptor |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat, bovine, sheep |
656,00 €
Artikelnummer: Cay11169-1
Fluprostenol isopropyl ester (Cay-16769) is a potent F-series prostaglandin receptor agonist prodrug that finds clinical use as an ocular hypotensive agent for the treatment of glaucoma. 13,14-epoxy Fluprostenol isopropyl ester (Cay-13679) is an impurity generated in the production of fluprostenol isopropyl ester....
Schlagworte: | 13(R),14(R)-epoxy Travoprost, Epoxy Derivative 1, (Z)-isopropyl... |
Anwendung: | FP receptor agonist |
CAS | 2557329-36-7 |
MW: | 516.6 D |
ab 152,00 €
Artikelnummer: Cay9002405-1
Tafluprost-d4 is intended for use as an internal standard for the quantification of tafluprost (Cay-10005440) by GC- or LC-MS. Tafluprost is a prodrug form of the FP receptor agonist tafluprost (free acid) (Cay-10005439) and a derivative of the prostaglandin F2alpha (PGF2alpha, Cay-16010, Cay-16020). It decreases...
Schlagworte: | AFP-168-d4,... |
Anwendung: | Tafluprost quantification, internal standard, GC, LC-MS |
MW: | 456.6 D |
ab 54,00 €