Anti-DSC3, CT (DSC3, CDHF3, DSC4, Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP) (Az

The protein encoded by this gene is a calcium-dependent_x000D_ glycoprotein that is a member of the desmocollin subfamily of the_x000D_ cadherin superfamily. These desmosomal family members, along with_x000D_ the desmogleins, are found primarily in epithelial cells where they_x000D_ constitute the adhesive proteins of the desmosome cell-cell_x000D_ junction and are required for cell adhesion and desmosome_x000D_ formation. The desmosomal family members are arranged in two_x000D_ clusters on chromosome 18, occupying less than 650 kb combined._x000D_ Alternative splicing results in two transcript variants encoding_x000D_ distinct isoforms. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.