Anti-CEP290 IHC Antibody, affinity purifie (IHC)

Anti-CEP290 IHC Antibody, affinity purifie (IHC)
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
IHC-00365-T 10 µl (5+ slides) -

3 - 9 Werktage*

131,00 €
IHC-00365 100 µl (50+ slides) -

3 - 9 Werktage*

493,00 €
 
Protein function: Involved in early and late steps in cilia formation. Its association with... mehr
Produktinformationen "Anti-CEP290 IHC Antibody, affinity purifie (IHC)"
Protein function: Involved in early and late steps in cilia formation. Its association with CCP110 is required for inhibition of primary cilia formation by CCP110 (PubMed:18694559). May play a role in early ciliogenesis in the disappearance of centriolar satellites and in the transition of primary ciliar vesicles (PCVs) to capped ciliary vesicles (CCVs). Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1 (PubMed:24421332). Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells, may play a role in ciliary transport processes. Required for efficient recruitment of RAB8A to primary cilium (PubMed:17705300). In the ciliary transition zone is part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition. Involved in regulation of the BBSome complex integrity, specifically for presence of BBS2, BBS5 and BBS8/TTC8 in the complex, and in ciliary targeting of selected BBSome cargos. May play a role in controlling entry of the BBSome complex to cilia possibly implicating IQCB1/NPHP5 (PubMed:25552655). Activates ATF4-mediated transcription (PubMed:16682973). [The UniProt Consortium]
Schlagworte: Anti-CT87, Anti-BBS14, Anti-CEP290, Anti-Cep290, Anti-Nephrocystin-6, Anti-Tumor antigen se2-2, Anti-Cancer/testis antigen 87, Anti-Centrosomal protein of 290 kDa, Anti-Bardet-Biedl syndrome 14 protein
Hersteller: Bethyl Laboratories
Hersteller-Nr: IHC-00365

Eigenschaften

Anwendung: ICC/IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human (Erwartet: Horse, Orangutan, Rhesus Monkey, Gorilla, African Elephant, Small-eared Galago, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by IHC-00365 maps to a region between residue 2429 and 2479 of human centrosomal protein 290kDa using the numbering given in entry NP_079390.3 (GeneID 80184).
Format: Antigen Affinity Purified

Handhabung & Sicherheit

Lagerung: +4°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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