Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
E-AB-61010.60 60 µl - -

7 - 16 Werktage*

149,00 €
E-AB-61010.120 120 µl - -

7 - 16 Werktage*

262,00 €
E-AB-61010.200 200 µl - -

7 - 16 Werktage*

459,00 €
The protein encoded by this gene is structurally very similar to the CDC46 protein from S.... mehr
Produktinformationen "Anti-CDC46"
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Interacts with MCMBP. [The UniProt Consortium]
Schlagworte: Anti-MCM5, Anti-CDC46, Anti-P1-CDC46, EC=, Anti-CDC46 homolog, Anti-DNA replication licensing factor MCM5, CDC46 Polyclonal Antibody
Hersteller: Elabscience
Hersteller-Nr: E-AB-61010


Anwendung: WB, IF
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Reaktivität: Human, Mouse, Rat
Immunogen: Recombinant protein of human MCM5

Handhabung & Sicherheit

Lagerung: -20°C
Versand: -20°C (International: -20°C)
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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