Anti-CD6, clone C6/372

1 mg/ml in sterile PBS, BSA free, sodium azide free. CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular ôscavenger receptor cysteine-richö (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. antibody to CD6 can be used to deplete T cells from bone marrow transplants to prevent graft versus host disease. Protein function: Involved in cell adhesion. Binds to CD166. [The UniProt Consortium]