Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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N6-Bz-5'-O-DMTr-2'-O-hexadecanyl Adenosine 3'-CED...
Item number: Cay43602-10
N6-Bz-5'-O-DMTr-2'-O-hexadecanyl adenosine 3'-CED phosphoramidite is a nucleoside building block containing a C16 alkyl chain at the 2'-position.. SMILES: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]([C@H](N5C6=NC=NC(NC(C7=CC=CC=C7)=O)=C6N=C5)O4)OCCCCCCCCCCCCCCCC. InChi...
| Keywords: | N6-Bz-5'-O-DMTr-2'-O-palmityl Adenosine 3'-CED Phosphoramidite, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]... |
| Application: | Lipid-containing nucleoside building block |
| CAS | 2382942-35-8 |
| MW: | 1098.38 D |
From 35.00€
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Versican G1 Domain (human, recombinant)
Item number: Cay44299-20
Versican is a secreted proteoglycan and member of the hyalectan family of proteoglycans. It is composed of an N-terminal G1 domain containing a secretory signal peptide, an immunoglobulin-like motif, and two proteoglycan tandem repeats followed by two glycosaminoglycan (GAG) binding regions, alpha-GAG and beta-GAG,...
| Keywords: | Chondroitin Sulfate Proteoglycan 2, Chondroitin Sulfate Proteoglycan Core Protein 2, CSPG2, ERVR, GHAP, Glial... |
| Application: | Binding assay, ELISA, WB |
From 244.00€
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Cannabigerolic Acid-d9
Item number: Cay44742-100
Cannabigerolic acid-d9 (Cay-44742) is intended for use as an internal standard for the quantification of cannabigerolic acid (Cay-20019, Cay-42523, Cay-9001572) by GC- or LC-MS. Cannabigerolic acid is categorized as a phytocannabinoid. It is a precursor in the biosynthesis of tetrahydrocannabinolic acid,...
| Keywords: | CBGA-d9, 3-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2,4-dihydroxy-6-(pentyl-2,2,3,3,4,4,5,5,5-d9)benzoic acid |
| Application: | GC-MS, LC-MS internal standard, quantification, phytocannabinoid |
| MW: | 369.55 D |
258.00€
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Raptin (human, recombinant)
Item number: Cay45023-10
Raptin is a sleep-inducible hormone and C-terminal fragment of reticulocalbin-2 (RCN2) with roles in food intake and obesity prevention in animal models. RCN2 is predominantly expressed by neurons in the paraventricular nucleus (PVN) of the hypothalamus, and this expression is increased during the sleep phase...
| Keywords: | C-terminus Cleaved From Reticulocalbin-2 (RCN2) (25-246), Raptin Hormone Derived From RCN2 |
| Application: | WB |
From 154.00€
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Phosphatidylethanolamine (sunflower)
Item number: Cay45088-1
Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It...
| Keywords: | Cephalin, PE (sunflower), 2-ammonioethyl ((R)-2,3-bis(((9Z,12Z)-octadeca-9,12-dienoyl)oxy)propyl) phosphate |
| Application: | Glycerophospholipid, phosphatidylcholine / arachidonoyl ethanolamide precursor |
| MW: | 740.02 D |
From 69.00€
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MOG (92-106) (mouse) (trifluoroacetate salt)
Item number: Cay45096-1
Myelin oligodendrocyte glycoprotein (MOG) (92-106) is an encephalitogenic peptide and a peptide fragment of MOG, a protein involved in demyelinating CNS disorders. MOG (92-106) induces relapsing-remitting experimental autoimmune encephalomyelitis (RR-EAE) in SJL/J mice that lack NK1.1+ T cells and express a Th2-low...
| Keywords: | Myelin Oligodendrocyte Glycoprotein (92-106) |
| Application: | Encephalitogenic peptide |
| MW: | 1824.9 D |
From 49.00€
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A1480LS
Item number: Cay45340-1
A1480LS is a peripherally biased inhibitor of diacylglycerol lipase alpha (DAGLalpha) and DAGLbeta (IC50s = 6 and 4 nM, respectively, in human brain membrane homogenates). It reduces levels of the DAGL-derived endocannabinoid 2-arachidonoyl glycerol (2-AG) in peripheral tissue but not in the brain in mice when...
| Keywords: | (S)-(2-benzyl-4-(6-(trifluoromethyl)pyrazin-2-yl)piperazin-1-yl)(5-phenyl-2H-indazol-2-yl)methanone |
| Application: | DAGLalpha / DAGLbeta peripherally biased inhibitor |
| MW: | 542.57 D |
From 116.00€
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NV03
Item number: Cay45383-1
NV03 is an inhibitor of the protein-protein interaction between E3 ubiquitin-protein ligase UHRF1 (UHRF1) and histone H3 trimethylated lysine 9 (H3K9Me3). It binds the tandem Tudor domain (TTD) of UHRF1 (Kd = 2.4 µM) and is selective for the UHRF1-TTD over a panel of 36 demethylases at 10 µM.. SMILES:...
| Keywords: | N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo-thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide |
| Application: | UHRF1-H3K9Me3 protein-protein interaction inhibitor |
| CAS | 2448341-58-8 |
| MW: | 389.52 D |
From 139.00€
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T Cell Lipid 15
Item number: Cay45491-1
T cell lipid 15 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing T cell lipid 15, encapsulating CD22 chimeric antigen receptor (CAR) mRNA, and conjugated to a CD8-targeting nanobody induce CAR presentation...
| Keywords: | 9-octadecenoic acid (9Z)-1,1'-[2-[[3-(dimethylamino)propyl][1,4-dioxo-4-[(1-propylheptyl)oxy]butyl]amino]-1,3-propanediyl]... |
| Application: | Ionizable cationic lipid |
| CAS | 3024023-96-6 |
| MW: | 945.51 D |
From 110.00€
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CAQK Targeting/Delivery Peptide (trifluoroacetate salt)
Item number: Cay45529-10
CAQK targeting/delivery peptide (CAQK peptide) is a four-amino acid synthetic peptide that interacts with versican and tenascin-R, proteoglycans that are upregulated in the brain extracellular matrix (ECM) in CNS injuries. Intravenous administration of CAQK peptide leads to its accumulation in injured brain tissue...
| Keywords: | CAQK Peptide, H-Cys-Ala-Gln-Lys-OH, L-cysteinyl-L-alanyl-L-glutaminyl-L-lysine |
| Application: | Brain injury-targeting peptide |
| MW: | 448.54 D |
From 89.00€
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Saxitoxin
Item number: Cay45566-500
Saxitoxin is a marine guanidinium toxin and voltage-gated sodium channel blocker (IC50 = 4.3 nM). It selectively binds to sodium channels in rat brain and skeletal muscle over rat heart homogenates (Kds = 0.114, 0.49, and 10 nM, respectively). Saxitoxin (3 and 10 µM) also inhibits L-type calcium channels in isolated...
| Keywords: | STX, (3aS,4R,10aS)-2,6-diamino-4-[[(aminocarbonyl)oxy]methyl]-3a,4,8,9-tetrahydro-1H,10H-pyrrolo[1,2-c]purine-10,10-diol |
| Application: | Marine guanidinium toxin, voltage-gated sodium channel blocker |
| CAS | 35523-89-8 |
| MW: | 299.29 D |
452.00€
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Hericene A
Item number: Cay45578-1
Hericene A is a polyketide synthase-derived geranyl resorcylate that has been found in H. erinaceus and has diverse biological activities. It is an inhibitor of alpha-glucosidase (IC50 = 6.7 µM). Hericene A (1-100 µM) decreases LPS-induced TNF-alpha, IL-6, and nitric oxide (NO) production in RAW 264.7 cells. It...
| Keywords: | 5'-Deoxohericenone C, hexadecanoic acid, [4-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-2... |
| Application: | Bioactive geranyl resorcylate |
| CAS | 157207-54-0 |
| MW: | 556.83 D |
From 110.00€
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