Products from BPS Bioscience
Sun, sea, and science: BPS Bioscience from San Diego, California promotes new scientific discoveries that lead to therapies by creating innovative solutions for research. BPS is an expert in recombinant proteins and enzymes, cell lines, virus-based tools, as well as biochemical and cellular assay systems. The high-quality products and services from BPS enable researchers worldwide to advance biological discoveries in a variety of disciplines, including epigenetics, cell signaling, SARS-CoV-2, immunotherapy, CRISPR, and adoptive cell therapies.
More information at: www.bpsbioscience.com
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Sotorasib
Item number: BPS-82712-1
Sotorasib (AMG-510) is a first-in-class, orally bioavailable, and selective KRAS G12C covalent inhibitor. Sotorasib irreversibly inhibits KRAS G12C by locking it in an inactive GDP-bound state. Sotorasib is the first KRAS G12C inhibitor in clinical development and leads to the regression of KRAS G12C tumors1,2.
| Keywords: | KRAS G12C inhibitor, Sotorasib, AMG-510, |
| Application: | Ras signaling, cancer therapy target |
| CAS | 2296729-00-3 |
| MW: | 560,59 D |
From 367.00€
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USP9X Inhibitor Screening Assay Kit
Item number: BPS-82726
The USP9X Inhibitor Screening Assay Kit is a fluorogenic assay kit designed to measure the activity of the deubiquitinating (DUB) enzyme USP9X (ubiquitin specific peptidase 9 X-linked) for screenin82726-1g and profiling applications. The kit contains enough purified USP9X, Ubiquitinated-AMC substrate, and assay...
| Keywords: | hFAM, DFFRX, Fat facets in mammals, Ubiquitin thioesterase FAF-X, Deubiquitinating enzyme FAF-X, Fat facets... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
1,123.00€
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eGFP/Firefly Luciferase MCF7 Cell Line
Item number: BPS-82730
eGFP/Firefly Luciferase MCF7 Cell Line is a MCF7 human breast mammary gland cell line engineered to express eGFP (enhanced green fluorescence protein) and Firefly luciferase driven by a CMV promoter. This cell line was generated by transduction with Firefly Luciferase-eGFP Lentivirus (#79980-P).
| Keywords: | Luciferase, Luciferin 4-monooxygenase, |
| Application: | Cellular viability assays, ER-positive xenograft cell line, fluorescence/bioluminescence imaging |
| Species reactivity: | human |
3,131.00€
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eGFP/Firefly Luciferase BCMA Knockout MM.1S Cell Line
Item number: BPS-82732
eGFP/Firefly Luciferase BCMA Knockout MM.1S Cell Line is a MM.1S cell Line constitutively expressing firefly (Photinus pyralis) luciferase and the enhanced GFP (eGFP) cassette under the control of a CMV promoter, where BCMA (B-Cell Maturation Antigen, or CD269) has been genetically removed using CRISPR/Cas9 genome...
| Keywords: | Luciferase, Luciferin 4-monooxygenase, |
| Application: | Cell killing assay control, CAR-T / CAR-NK cell B-cell target , CAR design optimization |
| Species reactivity: | human |
11,023.00€
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USP22 Inhibitor Screening Assay Kit
Item number: BPS-82742
The USP22 Inhibitor Screening Assay Kit is a fluorogenic assay kit designed to measure the activity of the deubiquitinating (DUB) enzyme USP22 (ubiquitin specific peptidase 22) for screening and profiling applications. The kit contains enough purified USP22, Ubiquitinated-AMC substrate, and assay buffer for 100...
| Keywords: | USP22, KIAA1063, Ubiquitin thioesterase 22, Deubiquitinating enzyme 22, Ubiquitin carboxyl-terminal hydrolase 22,... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
1,123.00€
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Vandortuzumab
Item number: BPS-82750-1
Vandortuzumab is a CHO-expressed humanized antibody targeting STEAP1. Vandortuzumab has a huIgG1 type heavy chain and a hukappa type light chain, with a predicted molecular weight (MW) of 148.74 kDa.
| Keywords: | Anti-STEAP1, Anti-PRSS24, Anti-STEAP1 protein, Anti-Six-transmembrane epithelial antigen of prostate 1, |
| Application: | Cancer therapy targets |
| Species reactivity: | human |
| MW: | 148,87 kD |
From 827.00€
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Chemi-Verse(TM) PDGFRalpha (D842Y) Kinase Assay Kit
Item number: BPS-82751
The Chemi-Verse(TM) PDGFRalpha (D842Y) Kinase Assay Kit is designed to measure PDGFRalpha (platelet-derived growth factor receptor A) (D842Y) tyrosine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough...
| Keywords: | CD140a, PDGFRA, PDGFR2, PDGFR-2, EC=2.7.10.1, PDGFR-alpha, PDGF-R-alpha, CD140a antigen, CD140 antigen-like family member... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
975.00€
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Chemi-Verse(TM) PDGFRalpha (D842I) Kinase Assay Kit
Item number: BPS-82752
The Chemi-Verse(TM) PDGFRalpha (D842I) Kinase Assay Kit is designed to measure PDGFRalpha (platelet-derived growth factor receptor A) (D842I) tyrosine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough...
| Keywords: | CD140a, PDGFRA, PDGFR2, PDGFR-2, EC=2.7.10.1, PDGFR-alpha, PDGF-R-alpha, CD140a antigen, CD140 antigen-like family member... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
975.00€
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Assay Medium 2F
Item number: BPS-82784-1
This liquid assay medium is optimized for use in cellular assays with selected BPS Bioscience cell lines.
| Application: | Cellular assay medium |
From 197.00€
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A-1155463
Item number: BPS-82803-1
A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell.1 A-1155463 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
| Keywords: | A-1155463, BCL-XL inhibitor, |
| Application: | Apoptosis studies |
| CAS | 1235034-55-5 |
| MW: | 669,79 D |
From 421.00€
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A-1210477
Item number: BPS-82805-1
A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45 nM1. A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner.2
| Keywords: | A-1210477, MCL-1 inhibitor, |
| Application: | Apoptosis studies |
| CAS | 1668553-26-1 |
| MW: | 850,04 D |
From 238.00€
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c-Myc: WDR5 [Biotinylated] Binding Chemiluminescent Assay...
Item number: BPS-82851
The c-Myc: WDR5 [Biotinylated] Binding Chemiluminescent Assay Kit is an ELISA designed to measure the binding between c-Myc and WDR5 (WD40 repeat domain 5) protein for screening and profiling applications. This kit comes with enough purified c-Myc (amino acids 2-454(end)) and biotinylated WDR5 (amino acids...
| Keywords: | MYC, bHLHe39, BHLHE39, Proto-oncogene c-Myc, Transcription factor p64, Myc proto-oncogene protein, Class E basic... |
| Application: | Inhibitor studies, compound screening, drug discovery, HTS |
| Species reactivity: | human |
2,341.00€
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