Products from BPS Bioscience
Sun, sea, and science: BPS Bioscience from San Diego, California promotes new scientific discoveries that lead to therapies by creating innovative solutions for research. BPS is an expert in recombinant proteins and enzymes, cell lines, virus-based tools, as well as biochemical and cellular assay systems. The high-quality products and services from BPS enable researchers worldwide to advance biological discoveries in a variety of disciplines, including epigenetics, cell signaling, SARS-CoV-2, immunotherapy, CRISPR, and adoptive cell therapies.
More information at: www.bpsbioscience.com
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PRAME TCR CD8+ NFAT-Luciferase Reporter Jurkat Cell Line
Item number: BPS-78997
PRAME TCR CD8+ NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and a PRAME (Preferentially Expressed Antigen in Melanoma)-directed TCR using lentiviral...
| Keywords: | OIP-4, Opa-interacting protein 4, Preferentially expressed antigen of melanoma, Melanoma antigen preferentially expressed... |
| Application: | Co-culture bioassay design/optimiz., positive control, vaccine T cell immunogenicity in vitro system |
| Species reactivity: | human |
16,374.00€
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CL2A-SN38
Item number: BPS-82256-1
CL2A-SN38 is a SN38 derivative with a Mal-PEG attached peptide linker, it can easily react with antibody to form an antibody-drug conjugate (ADC). SN-38 is a potent DNA Topoisomerase I inhibitor. CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A linker is...
| Application: | ADC payload, potent DNA Topoisomerase I inhibitor |
| MW: | 1480,6 D |
From 2,253.00€
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Eribulin
Item number: BPS-82265-1
Eribulin is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin suppresses centromere dynamics at concentrations that arrest mitosis.
| Application: | ADC payload, microtubule targeting agent |
| MW: | 729,9 D |
From 1,997.00€
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Auristatin PE
Item number: BPS-82268-1
Auristatin PE is a novel synthetic Dolastatin 10 derivative. Auristatin PE inhibits tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis.
| Keywords: | Soblidotin, |
| Application: | ADC payload, tubulin polymerization inhibitor, cell cycle arrest, apoptosis inducer |
| MW: | 702,0 D |
From 1,028.00€
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Dolastatin 10
Item number: BPS-82269-1
Dolastatin 10 is a potent antimitotic peptide that inhibits tubulin polymerization. Dolastatin 10 consists of four amino acids, in order from the amino terminus: dolavaline, valine, dolaisoleucine, and dolaproine.
| Application: | ADC payload, tubulin polymerization inhibitor, potent antimitotic peptide |
| MW: | 785,1 D |
From 1,448.00€
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MMAF
Item number: BPS-82270-1
Monomethyl auristatin F (MMAF) is an antitubulin agent that inhibits cell division by blocking the polymerization of tubulin. Because MMAF is highly toxic, it cannot be used as a drug itself. MMAF induces potent antitumor effects when conjugated via protease cleavable linkers to a monoclonal antibody targeting...
| Keywords: | Monomethyl auristatin F, |
| Application: | ADC payload, tubulin polymerization inhibitor, cell cycle arrest, toxin |
| MW: | 732,0 D |
From 1,154.00€
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MC-MMAF
Item number: BPS-82271-1
MC-MMAF is a precursor of antibody drug conjugate. Mal group is reactive with thiol bearing molecule. MMAF is a synthetic antineoplastic agent.
| Application: | ADC payload, synthetic antineoplastic agent |
| MW: | 925,2 D |
From 943.00€
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Auristatin E
Item number: BPS-82272-1
Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity, it is a synthetic analog of dolastatin 10. Auristatin E is a highly potent antimitotic agent.
| Application: | ADC payload, cytotoxic tubulin modifier, highly potent antimitotic agent |
| MW: | 732,0 D |
From 975.00€
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Influenza HA H3 Peptide (307-319)
Item number: BPS-82311
The Influenza HA H3 Peptide (307-319, PKYVKQNTLKLAT) is a peptide corresponding to the Influenza A virus subtype H3N2 HA (hemagglutinin), amino acids 307-319. The peptide is widely used to stimulate human H3N2 Influenza -specific CD4+ T cells.
| Application: | Human influenza H3N2-specific CD4+ T cell stimulation |
| Origin: | strain a/northern territory/60/1968 h3n2 |
340.00€
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Influenza HA H1 Peptide (Hawaii H1N1)
Item number: BPS-82312
The Influenza HA H1 Peptide (Hawaii H1N1, PKYVKSTKLRLAT) is a peptide from the Influenza virus subtype Hawaii H1N1 HA (hemagglutinin) H1. The peptide is used as a negative control in assays using Influenza HA H3 (307-319) peptide (BPS Bioscience #82311).
| Application: | Influenza HA H3 (307-319) peptide (BPS-82311) assay negative control |
| Origin: | a/mexico city/iner16/2009(h1n1 |
340.00€
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Vgamma4Vdelta1 TCR NFAT-Luciferase Reporter Jurkat Cell Line
Item number: BPS-82329
The Vgamma4Vdelta1 TCR NFAT-Luciferase Reporter Jurkat Cell Line was generated from the T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (#78556) by overexpression of human Vgamma4Vdelta1 TCR using lentiviral transduction (with Vgamma4Vdelta1 TCR Lentivirus #78986). This cell line was...
| Keywords: | T cell receptor delta constant, |
| Application: | Vgamma4Vdelta1 TCR agonist antibody screening, Vgamma4Vdelta1 TCR evaluation positive control, optim. |
| Species reactivity: | human |
17,040.00€
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DLL1 Lentivirus
Item number: BPS-82340
DLL1 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. These particles transduce cells with human DLL1 (delta like canonical notch ligand 1) (NM_005618.4), driven by a...
| Keywords: | Delta1, H-Delta-1, Delta-like protein 1, Drosophila Delta homolog 1, |
| Application: | Human DLL1 cell expression, cell pool/stable cell line generation, puromycin selection |
| Species reactivity: | human |
1,490.00€
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