Products from BellBrook Labs
BellBrook Labs is a leading provider of biochemical assay solutions for drug discovery and enzyme analysis. The company develops and markets innovative high-throughput screening (HTS) assays, validated enzymes and compatible reagents, and also supports customers with assay development, workflow validation and scientific services. With its proprietary Transcreener® and AptaFluor® platforms, BellBrook Labs enables sensitive, robust and user-friendly measurement methods for a wide range of enzymatic targets in pharmaceutical, biotech and academic research institutions.
More information at: www.bellbrooklabs.com
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Enzolution(R) DDX17 ATPase TR-FRET Assay System
Item number: BBL-3040-10K-TR
The Enzolution(R) DDX17 Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DDX17. DDX17, a DEAD box helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. It is involved in multiple cellular processes, including...
| Keywords: | DDX17, DEAD box protein 17, DEAD box protein p82, DEAD box protein p72, RNA-dependent helicase p72, Probable ATP-dependent... |
| Application: | HTS, drug discovery, enzyme assays |
From 864.00€
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Enzolution(R) DDX41 ATPase FP Assay System
Item number: BBL-3041-10K-FP
The Enzolution(R) DDX41 Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DDX41. DDX41, a DEAD box protein, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), is an ATP-dependent helicase that unwinds dsRNA and dsDNA. ADP...
| Keywords: | DDX41, DEAD box protein 41, DEAD box protein abstrakt homolog, Probable ATP-dependent RNA helicase DDX41 |
| Application: | HTS, drug discovery, enzyme assays |
From 1,549.00€
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Enzolution(R) DDX41 ATPase TR-FRET Assay System
Item number: BBL-3041-10K-TR
The Enzolution(R) DDX41 Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DDX41. DDX41, a DEAD box protein, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), is an ATP-dependent helicase that unwinds dsRNA and dsDNA. ADP...
| Keywords: | DDX41, DEAD box protein 41, DEAD box protein abstrakt homolog, Probable ATP-dependent RNA helicase DDX41 |
| Application: | HTS, drug discovery, enzyme assays |
From 1,594.00€
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Enzolution(R) DHX9 ATPase TR-FRET Assay System
Item number: BBL-3042-10K-TR
The Enzolution(R) DHX9 ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the ATP-dependent RNA helicase activity of DHX9, a member of the a DExH/D helicase family. Though it is classified as an RNA helicase, DHX9 also has been reported to unwind DNA and DNA:RNA hybrids. ADP...
| Keywords: | DHX9 Assay, DHX9 inhibitor screening kit |
| Application: | HTS, drug discovery, enzyme assays |
From 671.00€
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Transcreener(R) pADPr PARP FP Assay
Item number: BBL-3043-10K
The Transcreener(R) pADPr PARP FP Assay is a biochemical HTS assay for measuring the production of poly(ADP-ribose) (pADPr) in poly(ADP-ribose) polymerase (PARP) reactions. The assay relies on pADPr Coupling Enzymes (CE) to convert pADPr into AMP, which is then detected using a far-red, competitive fluorescence...
| Keywords: | PARP Activity Assay, PARP Inhibitor Screening Assay |
| Application: | HTS, drug discovery, enzyme assays |
| Species reactivity: | human |
From 1,253.00€
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Enzolution(R) PARP1 FP Assay System
Item number: BBL-3045-10K-FP
The Enzolution(R) PARP1 Assay System is intended for use with the Transcreener(R) pADPr PARP Assay Kits (Parts #3043 and #3044) to measure the enzymatic activity of PARP1 (poly(ADP-ribose) polymerase 1). PARP1 forms poly(ADP-ribose) (pADPr) chains on target proteins, including itself, using NAD+ as a donor...
| Keywords: | PARP1, Poly[ADP-ribose] synthase 1, Poly [ADP-ribose] polymerase 1, NAD(+) ADP-ribosyltransferase 1, DNA... |
| Application: | HTS, drug discovery, enzyme assays |
From 592.00€
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Enzolution(R) PARP1 TR-FRET Assay System
Item number: BBL-3045-10K-TR
The Enzolution(R) PARP1 Assay System is intended for use with the Transcreener(R) pADPr PARP Assay Kits (Parts #3043 and #3044) to measure the enzymatic activity of PARP1 (poly(ADP-ribose) polymerase 1). PARP1 forms poly(ADP-ribose) (pADPr) chains on target proteins, including itself, using NAD+ as a donor...
| Keywords: | PARP1, Poly[ADP-ribose] synthase 1, Poly [ADP-ribose] polymerase 1, NAD(+) ADP-ribosyltransferase 1, DNA... |
| Application: | HTS, drug discovery, enzyme assays |
From 626.00€
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Transcreener(R) OAADPr SIRT FP Assay
Item number: BBL-3046-10K
The Transcreener OAADPr SIRT FP Assay is a biochemical HTS assay for measuring the production of 2'-O-acetyl-ADP-ribose (OAADPr) by sirtuins (SIRT), NAD-dependent deacetylases. The assay relies on a Coupling Enzyme (CE) to convert OAADPr into AMP, which is then detected using a far-red, competitive fluorescence...
| Keywords: | SIRT Activity Assay, SIRTUIN Inhibitor Screening Assay |
| Application: | HTS, drug discovery, enzyme assays |
| Species reactivity: | human |
From 1,025.00€
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Transcreener(R) OAADPr SIRT TR-FRET Assay
Item number: BBL-3047-10K
The Transcreener OAADPr SIRT TR-FRET Assay is a biochemical HTS assay for measuring the production 2'-O-Acetyl-ADP-ribose (OAADPr) by sirtuins (SIRT), NAD-dependent deacetylases. The assay relies on a Coupling Enzyme (CE) to convert OAADPr into AMP, which is then detected using a far-red, competitive, time-resolved...
| Keywords: | SIRT Activity Assay, SIRTUIN Inhibitor Screening Assay |
| Application: | HTS, drug discovery, enzyme assays |
| Species reactivity: | human |
From 1,139.00€
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Enzolution(R) SIRT1 FP Assay System
Item number: BBL-3048-10K-FP
The Enzolution(R) SIRT1 Assay System is intended for use with the Transcreener(R) OAADPr SIRT Assay Kits (Parts #3046 and #3047) to measure the enzymatic activity of SIRT1 (NAD-dependent protein deacetylase sirtuin 1). SIRT1 catalyzes transfer of acetyl groups from lysine residues to NAD, yielding the unacetylated...
| Keywords: | SIRT1, SIR2-like protein 1, Regulatory protein SIR2 homolog 1, NAD-dependent protein deacylase sirtuin-1, NAD-dependent... |
| Application: | HTS, drug discovery, enzyme assays |
From 603.00€
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Enzolution(R) SIRT1 TR-FRET Assay System
Item number: BBL-3048-10K-TR
The Enzolution(R) SIRT1 Assay System is intended for use with the Transcreener(R) OAADPr SIRT Assay Kits (Parts #3046 and #3047) to measure the enzymatic activity of SIRT1 (NAD-dependent protein deacetylase sirtuin 1). SIRT1 catalyzes transfer of acetyl groups from lysine residues to NAD, yielding the unacetylated...
| Keywords: | SIRT1, SIR2-like protein 1, Regulatory protein SIR2 homolog 1, NAD-dependent protein deacylase sirtuin-1, NAD-dependent... |
| Application: | HTS, drug discovery, enzyme assays |
From 637.00€
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Enzolution(R) SIRT2 FP Assay System
Item number: BBL-3049-10K-FP
The Enzolution(R) SIRT2 Assay System is intended for use with the Transcreener(R) OAADPr SIRT Assay Kits (Parts #3046 and #3047) to measure the enzymatic activity of SIRT2 (NAD-dependent protein deacetylase sirtuin 2). SIRT2 catalyzes transfer of acetyl groups from lysine residues to NAD, yielding the unacetylated...
| Keywords: | SIRT2, SIR2-like protein 2, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent... |
| Application: | HTS, drug discovery, enzyme assays |
From 683.00€
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