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Product information "Transcreener(R) OAADPr SIRT TR-FRET Assay"
The Transcreener OAADPr SIRT TR-FRET Assay is a biochemical HTS assay for measuring the production 2'-O-Acetyl-ADP-ribose (OAADPr) by sirtuins (SIRT), NAD-dependent deacetylases. The assay relies on a Coupling Enzyme (CE) to convert OAADPr into AMP, which is then detected using a far-red, competitive, time-resolved Förster-resonance-energy-transfer (TR-FRET) assay. As an example, the Transcreener OAADPr SIRT TR-FRET assay can be used to detect the activity of human SIRT1 and SIRT2 using acetylated peptides as substrates.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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