Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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Flagellin (rec.)
Item number: AG-40B-0125-C010
The native flagellin [FliC] from Salmonella enterica Serovar Typhimurium strain ATCC14028 (aa 1-495) is fused at the N-terminus to a His-tag. Lyophilized. Contains PBS. Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the...
| Keywords: | flaF, fliC, STM1959, Flagellin, Phase 1-I flagellin |
| Application: | TLR5 activator, NLRC4 activator |
| Expressed in: | E.coli |
| Origin: | human, mouse |
From 198.00€
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Muristerone A
Item number: AG-CN2-0070-M001
Potent member of the ecdysteroid family - Ecdysone receptor (EcR) agonist - Analog of ecdysone with similar properties to ponasterone A (Prod. No. AG-CN2-0053) - Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals - Induces apoptosis in cells transfected with wild-type Bax...
| Keywords: | 2beta,3beta,5beta,11alpha,14alpha,20R,22R-Heptahydroxycholest-7-en-6-one |
| Application: | EcR agonist |
| Host: | Ipomoea hederacea |
| CAS | 38778-30-2 |
| MW: | 496,6 D |
From 66.00€
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4alpha-PMA
Item number: AG-CN2-0082-M001
Semi-synthetic. Negative control for phorbol ester activation of protein kinase C and studies with PMA (AG-CN2-0010). Might be a reasonable PKC-independent TRPV4 channels agonist.
| Keywords: | 4alpha-PMA, 4alpha-TPA, 4alpha-12-O-Tetradecanoylphorbol 13-acetate |
| Application: | TRPV4 channels agonist |
| CAS | 63597-44-4 |
| MW: | 616,8 D |
77.00€
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Atpenin A5
Item number: AG-CN2-0100-C250
Antibiotic, antifungal, potent and specific mitochondrial complex II (succinate-ubiquinone oxidoreductase) inhibitor, mitochondrial ATP-sensitive potassium (mK(ATP)) channel activator, cardioprotective, modulates mitochondrial ROS generation during cardioprotection
| Keywords: | 3-[(2S,4S,5R)-5,6-Dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1H)-pyridinone |
| Application: | Succinate-ubiquinone oxidoreductase inhibitor |
| CAS | 119509-24-9 |
| MW: | 366,2 D |
From 143.00€
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Helenalin
Item number: AG-CN2-0435-M001
Anticancer compound. NF-kappaB inhibitor. Apoptosis inducer. Potent anti-inflammatory agent. Telomerase inhibitor. Anti-trypanosomal and antiprotozoal compound Antibiotic. Shows anti-proliferative effects in 3T3-L1 preadipocytes. Autophagy inducer.
| Keywords: | Helenalin A, NSC 85236 |
| Application: | Antiinflammatory, NF-kappaB mediated gene expression inhibitor |
| CAS | 6754-13-8 |
| MW: | 262.3 D |
From 286.00€
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Amorfrutin A
Item number: AG-CN2-0462-C500
Solid. Soluble in DMSO, ethanol or methanol. Insoluble in water. Antidiabetic agent, Potent and selective partial agonist of peroxisome proliferator-activated receptor gamma (PPARgamma), a nuclear receptor regulating lipid and glucose metabolism. Has nanomolar binding affinity to PPARgamma and micromolar binding to...
| Keywords: | 2-Hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-phenethylbenzoic acid |
| Application: | Antidiabetic agent, PPARgamma partial agonist |
| CAS | 80489-90-3 |
| MW: | 340,4 D |
220.00€
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Q-VE-OPh (Negative Control for Q-VD-OPh)
Item number: AG-CP3-0007-M001
Synthetic. Soluble in DMSO. Cell permeable, non-toxic negative control for the caspase inhibitor Q-VD-OPh (Prod. No. AG-CP3-0006). Stable in aqueous environment. Several folds less inhibitory activity than Q-VD-OPh. Perfect for both in vitro and in vivo studies.
| Keywords: | Q-Val-Glu-Oph, N-(2-Quinolyl)-L-valyl-L-glutamyl-(2,6-difluorophenoxy) methylketone |
| Application: | pan-Caspase Inhibitor (Negative Control) |
| MW: | 527,5 D |
176.00€
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OCH
Item number: AG-CR1-3593-M001
White to off-white solid. Soluble in DMSO, 100% ethanol (warm) or methanol (warm). Truncated analog of alpha-GalCer, iNKT cell glycolipid agonist, Immunosuppressive, Th2 polarizing. Stimulation of NKT with OCH results in release of primarily Th2 cytokine compared to stimulation with alpha-GalCer, which results in...
| Keywords: | (2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-N-tetracosanoyl-2-amino-1,3,4-nonanetriol) |
| Application: | alpha-galactosylceramide analog |
| CAS | 383187-82-4 |
| MW: | 704 D |
From 165.00€
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AMC Standard Solution
Item number: AG-CS1-0105-R100
Liquid. A fluorogenic standard useful for quantitating assays monitoring amido-4-methylcoumarin (AMC) release. These include ubiquitin-AMC, SUMO-1-AMC, NEDD8-AMC, ISG15-AMC and proteasome substrates. The concentration of the AMC released can be calculated from a standard curve prepared with AMC standards.
| Keywords: | 7-Amino-4-methylcoumarin, Coumarin 120 |
| Application: | Fluorogenic standard |
| CAS | 26093-31-2 |
| MW: | 175,2 D |
111.00€
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BQ-123 sodium salt
Item number: AG-CP3-0001-M001
Potent and selective endothelin receptor A (ETA) antagonist, suppresses the ET-1-induced decrease of LPL activity, shows protective effects in ischemic acute renal failure, neuroprotective, anti-hypertensive, inhibits ET-1 receptor binding and blocks Ca2 mobilization, cellular contraction and MAP kinase activation,...
| Keywords: | Endothelin Receptor A Antagonist BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu) Na |
| Application: | Endothelin receptor A antagonist |
| CAS | 136553-81-6 |
| MW: | 609,7 D |
From 116.00€
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BIX 01294
Item number: AG-CR1-0051-M001
Selective and cell permeable G9a histone lysine methyltransferase (HMTase) inhibitor. Pluripotent stem cell inducer.
| Keywords: | 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]4-quinazolinamine |
| Application: | HMTase inhibitor |
| CAS | 935693-62-2 |
| MW: | 490,6 D |
From 36.00€
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Gardiquimod
Item number: AG-CR1-3583-M005
Synthetic. Immune response modifier. Antiviral and antitumor compound Selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-kappaB in HEK 293 cells expressing TLR7 at 0.1µg/ml. 10 times more active than Imiquimod (Prod. No. AG-CR1-3569). At high concentrations (3µg/ml)...
| Keywords: | 1-(4-Amino-2-ethylaminomethylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol |
| Application: | TLR7 ligand |
| CAS | 1020412-43-4 |
| MW: | 313,4 D |
From 50.00€
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