Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Aprepitant
Item number: TGM-T1743-50mg
Description: Aprepitant (Aprepitant`) is a Substance P/Neurokinin-1 Receptor Antagonist. The mechanism of action of aprepitant is as a Neurokinin 1 Antagonist, and Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 3A4 Inducer. Target: Neurokinin receptor, HIV Protease,...
| Keywords: | Aprepitant`, MK-0869, L-754030, MK-869 |
| Application: | Targets tachykinin receptor 1 (TACR1) |
| CAS | 170729-80-3 |
| MW: | 534.43 D |
From 46.00€
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Nintedanib
Item number: TGM-T1777-200mg
Description: Nintedanib (Intedanib) is a triple vascular kinase inhibitor that inhibits VEGFR1, VEGFR2, and VEGFR3 (IC50=34/13/13 nM), FGFR1, FGFR2, and FGFR3 (IC50=69/37/108 nM), PDGFRalpha, and PDGFRbeta (IC50=59/65 nM). Nintedanib has antitumor activity and inhibits tumor growth by inhibiting angiogenesis....
| Keywords: | BIBF 1120, Intedanib |
| Application: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| CAS | 656247-17-5 |
| MW: | 539.62 D |
From 37.00€
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Quercetin Dihydrate
Item number: TGM-T6630-500mg
Description: Quercetin Dihydrate (Sophoretin) is a polyphenolic flavonoid that was found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine. It is used for their nervous system and anticancer effects. Target: Apoptosis, PI3K. Smiles: O.O.Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O....
| Keywords: | Sophoretin |
| CAS | 6151-25-3 |
| MW: | 338.27 D |
From 44.00€
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Dabigatran
Item number: TGM-T6295-1mg
Description: Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation. Target: Thrombin. Smiles:...
| Keywords: | BIBR 953ZW, BIBR 953 |
| Application: | Targets coagulation factor II (thrombin) [EC:3.4.21.5] (F2) |
| CAS | 211914-51-1 |
| MW: | 471.51 D |
From 35.00€
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ISRIB
Item number: TGM-T2027-5mg
Description: ISRIB is a potent and selective PERK inhibitor. Target: PERK. Smiles: Clc1ccc(OCC(=O)NC2CCC(CC2)NC(=O)COc2ccc(Cl)cc2)cc1. References: Sidrauski C, et al. Elife. 2013, 2, e00498.
| CAS | 548470-11-7 |
| MW: | 451.34 D |
From 46.00€
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Penicillin-Streptomycin Solution (100×), Sterile
Item number: TGM-C0051-100mL
Description: Penicillin-streptomycin solution, also known as Pen-Strep, is the most commonly used combined antibiotic solution against both gram-positive and gram-negative bacteria. Penicillin can directly interfere with the synthesis of bacterial cell wall and indirectly alter the cell wall by triggering enzymatic...
28.00€
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Dexamethasone
Item number: TGM-T1076-50mg
Description: Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages. Target: Complement System, ADC Cytotoxin, Antibacterial,...
| Keywords: | MK 125, NSC 34521, Prednisolone F, Hexadecadrol |
| CAS | 50-02-2 |
| MW: | 392.46 D |
From 29.00€
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Gabapentin
Item number: TGM-T0702-10mg
Description: Gabapentin (Neurontin) is an Anti-epileptic Agent. The physiologic effect of gabapentin is by means of Decreased Central Nervous System Disorganized Electrical Activity. Target: GABA Receptor, Calcium Channel. Smiles: NCC1(CC(O)=O)CCCCC1. References: Fink K, et al. Neuropharmacology, 2002, 42(2), 229-236.
| Keywords: | Gabapentine, Aclonium, Neurontin |
| CAS | 60142-96-3 |
| MW: | 171.24 D |
From 30.00€
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Triflusal
Item number: TGM-T0705-5mg
Description: Triflusal (UR1501) is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative. Target: COX, PDE, PPAR. Smiles: CC(=O)Oc1cc(ccc1C(O)=O)C(F)(F)F. References: Duran X, et al. J Thromb Haemost, 2008, 6(8), 1385-1392.
| Keywords: | UR1501 |
| CAS | 322-79-2 |
| MW: | 248.16 D |
From 38.00€
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Sulfisoxazole
Item number: TGM-T0750-1g
Description: Sulfisoxazole (Sulfafurazole) is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.Sulfisoxazole inhibits breast cancer exosome release by targeting endothelin receptor A. Target: Endothelin Receptor, Autophagy, Antibacterial,...
| Keywords: | Sulfafurazole, NU-445 |
| CAS | 127-69-5 |
| MW: | 267.3 D |
From 29.00€
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DFP00173
Item number: TGM-T11014-10mg
Description: DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor, with an IC50 of approximately 0.1-0.4 µM for both mouse and human AQP3. It demonstrates selectivity for AQP3 compared to homologous AQP subtypes AQP7 and AQP9. Target: Aquaporin. Smiles: [O-][N+](=O)c1cc(NC(=O)Nc2c(Cl)cccc2Cl)cs1....
| CAS | 672286-03-2 |
| MW: | 332.16 D |
From 62.00€
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RS 61443
Item number: TGM-T0245-1g
Description: RS 61443 (Mycophenolate mofetil) is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). Target: Dehydrogenase. Smiles: O=C(OCCN1CCOCC1)CC/C(C)=C/CC2=C(O)C3=C(COC3=O)C(C)=C2OC. References: Zwerner J , Fiorentino D . Mycophenolate...
| Keywords: | RS61443, Mycophenolate mofetil, TM-MMF |
| CAS | 115007-34-6 |
| MW: | 433.5 D |
From 30.00€
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