Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
Feretoside
Item number: TGM-TQ0280-100mg
Description: Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1). Target: HSP. Smiles: O([C@H]1[C@]2([C@@](C(C(OC)=O)=CO1)([C@H](O)C=C2CO)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O. References: Nam JW, et al. Heat shock...
| CAS | 27530-67-2 |
| MW: | 404.37 D |
From 67.00€
*
Avosentan
Item number: TGM-TQ0282-100mg
Description: Avosentan (Ro 67-0565) is an effective and selective antagonist of the endothelin receptor (ETA receptor). Target: Endothelin Receptor. Smiles: COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1. References: Baltatu OC, Iliescu R, Zaugg CE, Reckelhoff JF, Louie P, Schumacher C, Campos LA....
| Keywords: | Ro 67-0565, SPP-301 |
| CAS | 290815-26-8 |
| MW: | 479.51 D |
From 33.00€
*
RS102895
Item number: TGM-TQ0283-100mg
Description: RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1. Target: CCR. Smiles: O=C1OC2(C=3C(N1)=CC=CC3)CCN(CCC4=CC=C(C(F)(F)F)C=C4)CC2. References: Mirzadegan T, et al. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a...
| CAS | 300815-41-2 |
| MW: | 390.4 D |
From 36.00€
*
Hydroxyphenyllactic acid
Item number: TGM-TQ0284-100mg
Description: Hydroxyphenyllactic acid is an antifungal metabolite, fungi such as Lactobacillus sp. SK007. Target: Antifungal, Endogenous Metabolite. Smiles: OC(Cc1ccc(O)cc1)C(O)=O. References: Mu W, et al. Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation. J Biosci Bioeng. 2010...
| CAS | 306-23-0 |
| MW: | 182.17 D |
From 36.00€
*
Spaglumic acid acetate
Item number: TGM-TQ0285L-100mg
Description: Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain. Target: Endogenous Metabolite. Smiles: OC(CC[C@@H](C(O)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)=O.CC(O)=O. References: Coyle JT. The nagging question of the function of N-acetylaspartylglutamate....
| Keywords: | Isospaglumic acid acetate, Spaglumic acid acetate(3106-85-2 Free base) |
| MW: | 364.31 D |
From 48.00€
*
MK-0557
Item number: TGM-TQ0286-100mg
Description: MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM). Target: Neuropeptide Y Receptor. Smiles: Fc1ccccc1-n1ccc(NC(=O)[C@H]2CC[C@]3(CC2)OC(=O)c2ccncc32)n1. References: Fichtner M, et al. Discovery and evaluation of spirocyclic derivatives as antagonists of...
| Application: | NPY5R antagonist |
| CAS | 328232-95-7 |
| MW: | 406.41 D |
From 30.00€
*
Chrysin-7-O-glucuronide
Item number: TGM-TQ0287-10mg
Description: Chrysin-7-O-glucuronide (Chrysin 7-O-beta-D-glucopyranuronoside) is a natural product, with antioxidant activity. Target: Others, Antioxidant. Smiles: O[C@H]1[C@H](Oc2cc(O)c3c(c2)oc(cc3=O)-c2ccccc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O. References: Li K, et al. Inhibitory effects against alpha-glucosidase...
| Keywords: | Chrysin 7-O-beta-D-glucopyranuronoside |
| CAS | 35775-49-6 |
| MW: | 430.36 D |
From 53.00€
*
Hexahydrocurcumin
Item number: TGM-TQ0288-100mg
Description: Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1. Target: Reactive Oxygen Species, ROS, COX. Smiles: COc1cc(CCC(O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O. References: Srimuangwong K, et al. Hexahydrocurcumin enhances inhibitory effect of 5-fluorouracil on HT-29 human...
| Application: | COX-2 inhibitor |
| CAS | 36062-05-2 |
| MW: | 374.43 D |
From 76.00€
*
Firategrast
Item number: TGM-TQ0291-100mg
Description: Firategrast (SB 683699) is an orally active and specific alpha4beta1/alpha4beta7 integrin antagonist that reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity. It is used in relapsing-remitting multiple sclerosis, associated with...
| Keywords: | SB 683699 |
| Application: | Targets integrin alpha 4 (ITGA4, CD49d) |
| CAS | 402567-16-2 |
| MW: | 499.5 D |
From 38.00€
*
Grapiprant
Item number: TGM-TQ0292-100mg
Description: Grapiprant (AAT-007) is a selective EP4 receptor antagonist. Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor (IC50: 35 nM, Ki: 24 nM). Target: Prostaglandin Receptor. Smiles: CCc1nc2c(C)nc(C)cc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1. References: Vito VD, et al....
| Keywords: | AAT-007, CJ-023423, RQ-00000007 |
| Application: | Targets prostaglandin E receptor 4 (PTGER4) |
| CAS | 415903-37-6 |
| MW: | 491.61 D |
From 30.00€
*
AV-412 free base
Item number: TGM-TQ0293-2mg
Description: AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2). Target: EGFR. Smiles: CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C. References: Suzuki T, et al. Pharmacological characterization of MP-412...
| Keywords: | MP-412 free base |
| Application: | EGFR / ErbB2 inhibitor |
| CAS | 451492-95-8 |
| MW: | 507 D |
62.00€
*
Coumestrol
Item number: TGM-TQ0295-10mg
Description: Coumestrol that existed in soybean products suppresses the proliferation of ES2 cells (IC50: 50 µM). It exhibits activities against neurological disorders, cancers and autoimmune diseases. Target: Estrogen Receptor/ERR. Smiles: Oc1ccc2c(c1)oc1c2c(=O)oc2cc(O)ccc12. References: Zafar A, et al. Cytotoxic...
| Application: | 17-beta-hydroxysteroid oxidoreductase inhibitor |
| CAS | 479-13-0 |
| MW: | 268.22 D |
From 39.00€
*