Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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2',3',5'-Tri-O-(t-butyldimethylsilyl)-4'-C-hydroxymethyl...
Item number: TGM-TNU0949-100mg
Description: Nucleoside Derivative -4'-Modified nucleosides, Protected nucleosides with NH2/OH group. Target: Others. Smiles: C(O[Si](C(C)(C)C)(C)C)[C@]1(CO)[C@@H](O[Si](C(C)(C)C)(C)C)[C@@H](O[Si](C(C)(C)C)(C)C)[C@@H](O1)N2C(=O)NC(=O)C=C2
| CAS | 232588-97-5 |
| MW: | 617.01 D |
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2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine
Item number: TGM-TNU0950-100mg
Description: 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a fluoro-modified nucleoside, specifically a 5-modified pyrimidine nucleoside and 2'-modified nucleoside. Target: Others. Smiles: F[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2
| CAS | 182495-81-4 |
| MW: | 363.34 D |
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N6-Benzoylarabinoadenosine
Item number: TGM-TNU0951-100mg
Description: Nucleoside Derivatives - Arabino-nucleosides. Target: Others. Smiles: O[C@@H]1[C@H](N2C=3C(N=C2)=C(NC(=O)C4=CC=CC=C4)N=CN3)O[C@H](CO)[C@H]1O
| CAS | 79896-97-2 |
| MW: | 371.35 D |
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2'-Fluoro-5MeC (Bz)-3'-phosphoramidite
Item number: TGM-TNU0952-100mg
Description: 2'-Fluoro-5MeC (Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite. Target: Others. Smiles: C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@@H](O1)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2)(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6
| CAS | 182495-83-6 |
| MW: | 865.92 D |
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Neopterin
Item number: TGM-TQ0273-100mg
Description: D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-gamma. In humans, neopterin is involved in purine biosynthesis. Target: Endogenous Metabolite. Smiles: Nc1nc2ncc(nc2c(=O)[nH]1)[C@H](O)[C@H](O)CO. References: Murr C, et al....
| Keywords: | 2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one, D-(+)-Neopterin |
| CAS | 2009-64-5 |
| MW: | 253.21 D |
From 46.00€
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LysoPC(14:0/0:0)
Item number: TGM-TQ0275-100mg
Description: LysoPC(14:0/0:0) is a lysophospholipid (LyP) and mono-glycerophospholipid. Target: Endogenous Metabolite, Others. Smiles: CCCCCCCCCC CCCC(=O)OC[C@@H](O)COP([O-])(=O)OCC[N+](C)(C)C. References: Tsukatani H, et al.Comparison of antispasmodic effect of synthetic lysolecithins with various fatty acid...
| Application: | Lipid signaling |
| CAS | 20559-16-4 |
| MW: | 467.58 D |
From 38.00€
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Methysticin
Item number: TGM-TQ0276-5mg
Description: Methysticin, a major kavalactone extracted from kava, can induce CYP1A1. Target: P450. Smiles: C(=C/C1CC(OC)=CC(=O)O1)\C=2C=C3C(=CC2)OCO3. References: Li Y, et al. Methysticin and 7,8-dihydromethysticin are two major kavalactones in kava extract to induce CYP1A1. Toxicol Sci. 2011 Dec,124(2):388-99.
| Keywords: | (±)-Methystici, DL-Methysticin |
| CAS | 20697-20-5 |
| MW: | 274.27 D |
660.00€
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Pralsetinib HCl (2097132-94-8 free base)
Item number: TGM-TQ0277L-100mg
Description: Pralsetinib is a selective and next-generation RET inhibitor (IC50: 0.3-0.4 nM for WT RET, RET mutants V804L, V804M, M918T, and CCDC6-RET fusion). BLU-667 is an effective and selective inhibitor of RET mutations, fusions, and predicted resistant mutants. Target: Others. Smiles:...
| Keywords: | Pralsetinib hydrochloride, Pralsetinib HCl, BLU667, BLU-667, BLU 667 |
| MW: | 570.07 D |
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Feretoside
Item number: TGM-TQ0280-100mg
Description: Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1). Target: HSP. Smiles: O([C@H]1[C@]2([C@@](C(C(OC)=O)=CO1)([C@H](O)C=C2CO)[H])[H])[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O. References: Nam JW, et al. Heat shock...
| CAS | 27530-67-2 |
| MW: | 404.37 D |
From 67.00€
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Avosentan
Item number: TGM-TQ0282-100mg
Description: Avosentan (Ro 67-0565) is an effective and selective antagonist of the endothelin receptor (ETA receptor). Target: Endothelin Receptor. Smiles: COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1. References: Baltatu OC, Iliescu R, Zaugg CE, Reckelhoff JF, Louie P, Schumacher C, Campos LA....
| Keywords: | Ro 67-0565, SPP-301 |
| CAS | 290815-26-8 |
| MW: | 479.51 D |
From 33.00€
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RS102895
Item number: TGM-TQ0283-100mg
Description: RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1. Target: CCR. Smiles: O=C1OC2(C=3C(N1)=CC=CC3)CCN(CCC4=CC=C(C(F)(F)F)C=C4)CC2. References: Mirzadegan T, et al. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a...
| CAS | 300815-41-2 |
| MW: | 390.4 D |
From 36.00€
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Hydroxyphenyllactic acid
Item number: TGM-TQ0284-100mg
Description: Hydroxyphenyllactic acid is an antifungal metabolite, fungi such as Lactobacillus sp. SK007. Target: Antifungal, Endogenous Metabolite. Smiles: OC(Cc1ccc(O)cc1)C(O)=O. References: Mu W, et al. Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation. J Biosci Bioeng. 2010...
| CAS | 306-23-0 |
| MW: | 182.17 D |
From 36.00€
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