Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Brallobarbital calcium
Item number: TGM-T202739-10mg
Description: Brallobarbital, known for its sedative and hypnotic properties, is a component of Vesparax used to treat sleep disorders. However, studies have identified Brallobarbital as the cause of toxicity issues associated with Vesparax. Smiles:...
| Keywords: | Brallobarbital |
| MW: | 306.14 D |
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Bucrylate
Item number: TGM-T202741-10mg
Description: Bucrylate (isobutyl cyanoacrylate) is a liquid tissue adhesive used for catheter embolization. Smiles: N#CC(=C)C(=O)OCC(C)C
| Keywords: | ISOBUTYL CYANOACRYLATE , BUCRILATE |
| MW: | 153.18 D |
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Clesacostat tromethamine
Item number: TGM-T202745-10mg
Description: Clesacostat (PF-05221304) is a potent and selective ACC inhibitor, with hACC1 IC50 of 13 nM and hACC2 IC50 of 9 nM. In animal models, PF-05221304 specifically inhibits hepatic DNL and demonstrates a significant safety margin for thrombocytopenia in non-human primate models. Smiles:...
| Keywords: | QF09CQF4SR , PF-05221304 tromethamine |
| MW: | 623.7 D |
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Clodazon hydrochloride anhydrous
Item number: TGM-T202748-10mg
Description: AW 142446 (Clodazon) is an antidepressant compound. Smiles: Cl.O=C1N(C=2C=CC=CC2)C3=CC(Cl)=CC=C3N1CCCN(C)C
| Keywords: | AW142446 , AW 142446 , Clodazon |
| MW: | 366.29 D |
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SHP2 inhibitor CNBDA
Item number: TGM-T202752-10mg
Description: SHP2 inhibitor CNBDA is a novel SHP2 inhibitor with an IC50 value of 5 µM, demonstrating significant efficacy against breast cancer cells. Smiles: O=C(O)C=1C=CC(=CC1)C2=CC(=C(OCCCCCCCCC)C(=C2)CCCC(=O)O)CCCC(=O)O
| Keywords: | CNBDA, SHP2 In CNBDA, SHP2-In-CNBDA |
| MW: | 512.63 D |
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Disuprazole
Item number: TGM-T202756-10mg
Description: Disuprazole is a compound that inhibits gastric acid secretion, classified as a 4-ethylthio-3-methylpyridine analog and functions as a proton pump inhibitor. Smiles: O=S(C1=NC=2C=CC=CC2N1)CC3=NC=CC(SCC)=C3C
| MW: | 331.46 D |
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Emavusertib Mesylate
Item number: TGM-T202763-10mg
Description: Emavusertib Mesylate (also known as CA-4948) is a potent inhibitor of IRAK4 and FLT3, demonstrating antitumor activity. In cell lines of ABC DLBCL and AML, CA-4948 shows significant cellular activity. Moreover, it exhibits moderate to high selectivity in screening assays of 329 kinases and has...
| MW: | 587.61 D |
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JANEX-1-M
Item number: TGM-T202764-10mg
Description: JANEX-1 is a JAK inhibitor metabolized by cytochrome P450 enzymes CYP1A1 and CYP1A2. The formation of JANEX-1-M follows Michaelis-Menten kinetics when in the presence of CYP1A1 and CYP1A2 expressed via baculovirus. Smiles: OC1=CC=C(C=C1)NC=2N=CN=C3C=C(O)C(OC)=CC32
| Keywords: | 7-O-DEMETHYLJANEX-1 , JANEX1M , JANEX 1 M |
| MW: | 283.28 D |
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RO-02-70608
Item number: TGM-T202770-10mg
Description: RO-02-70608 is the active metabolite of R411. Following a single oral dose escalation of R411, the area under the concentration-time curve for RO-02-70608 increases proportionally from 150 mg to 1200 mg (P > .05). Smiles: C(N[C@@H](CC1=CC=C(NC(=O)C=2C(Cl)=CN=CC2Cl)C=C1)C(O)=O)(=O)C3=C(C)C=CC=C3Cl
| Keywords: | RO 02-70608 , RO0270608 |
| MW: | 506.77 D |
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Ro 44-3888
Item number: TGM-T202774-10mg
Description: Ro 44-3888, the active component of sibrafiban, achieves predictable plasma concentrations when administered orally in its prodrug form, Ro 48-3657. Upon reaching a steady state after the second dose, Ro 44-3888 exhibits concentration-dependent inhibition of platelet aggregation and prolongs bleeding...
| Keywords: | RO-44-3888 , RO443888 |
| MW: | 376.41 D |
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Indolapril diacid
Item number: TGM-T202775-10mg
Description: Indolapril (CI-907) is a novel orally active prodrug classified as a non-thiol angiotensin-converting enzyme (ACE) inhibitor. Smiles: C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)C)(=O)N2[C@@]3([C@](C[C@H]2C(O)=O)(CCCC3)[H])[H]
| MW: | 402.48 D |
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RTI-51
Item number: TGM-T202777-10mg
Description: RTI-51 significantly enhances locomotor activity and holds potential as a treatment compound for cocaine use. It exhibits a highly effective, selective, and long-lasting substitution effect, which can reduce drug-seeking behavior. Smiles: C(OC)(=O)[C@H]1[C@H](C[C@]2(N(C)[C@@]1(CC2)[H])[H])C3=CC=C(Br)C=C3
| Keywords: | RTI4229-51 , RTI-4229-51 , RTI51 |
| MW: | 338.24 D |
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