Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Indatuximab
Item number: TGM-T77377-10mg
Description: Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine. Target: Integrin. References: Finks SW, et al. Idarucizumab (Praxbind): The First Reversal Agent for a Direct Oral Anticoagulant. Am J Med. 2017 May,130(5):e195-e197.
| MW: | 145.5 kD |
From 235.00€
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LY2928057
Item number: TGM-T77383-10mg
Description: LY2928057 is a humanized monoclonal antibody targeting the iron transporter SLC40A1, an iron-regulatory inhibitor used in cardiovascular disease research. Target: Ferroportin. Smiles: #N/A. References: Ramakrishnan L, et al. The Hepcidin/Ferroportin axis modulates proliferation of pulmonary artery...
| Keywords: | LY 2928057 |
| MW: | 145.5 D |
From 422.00€
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RI-962
Item number: TGM-T73493-100mg
Description: RI-962 is a potent and selective inhibitor of RIPK1 that dose-dependently protects cells from necrotic apoptosis induced by TNFalpha, Smac mimics, and Z-VAD-FMK by inhibiting RIPK1, RIPK3, and MLKL phosphorylation with EC50=10.0 nM~17.8 nM, and improves survival in mice in two models of inflammation....
| Keywords: | RI962 |
| MW: | 480.56 D |
From 276.00€
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SABA1
Item number: TGM-T73531-10mg
Description: SABA1 exhibits antibacterial activity, inhibiting Pseudomonas aeruginosa and Escherichia coli, and suppresses biotin carboxylase, making it useful for studying biological resistance. Target: Antibacterial, Antibiotic. Smiles: O=C(OCC)C1=CC=C(C=C1)NS(=O)(=O)C2=CC(=CC=C2Cl)C(=O)NC=3C=CC=CC3. References:...
| Keywords: | SABA-1 |
| MW: | 458.92 D |
From 61.00€
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Acetoacetic acid
Item number: TGM-T73734-10mg
Description: Acetoacetic acid (3-oxobutanoic acid) is a beta-keto acid and oxidative stress inducer, produced in the body when poor hepatic metabolism leads to excessive catabolism of fatty acids, is involved in the process of gluconeogenesis, and can be used as an indicator of in ketoacidosis. Target: Endogenous...
| Keywords: | 3-oxobutanoic acid |
| MW: | 102.09 D |
From 57.00€
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Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside
Item number: TGM-T73745-10mg
Description: Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside (pNP-G7) is a substrate for alpha-amylase, used to measure alpha-amylase activity. Target: Others, Amylase. Smiles:...
| Keywords: | Ethyliden-4-nitrophenyl-alpha-D-maltoheptaosid , pNP-G7 , Ethylidene-4-NP-G7 |
| MW: | 1300.13 D |
From 29.00€
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A-836339
Item number: TGM-T7375-200mg
Description: A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in mice. Target: Cannabinoid Receptor. Smiles:...
| MW: | 310.45 D |
From 30.00€
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Zymosterol
Item number: TGM-T73808-1mg
Description: Zymosterol, a metabolite in cholesterol biosynthesis and precursor to cholesterol, predominantly resides in the plasma membrane and circulates within the cell [1] [2]. Target: Endogenous Metabolite, Others. Smiles: [H][C@@]1(CC[C@@]2([H])C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C[C@]1([H])CC3)[C@H](C)CCC=C(C)C
| MW: | 384.64 D |
608.00€
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TRFS-green
Item number: TGM-T73825-1mg
Description: TRFS-green, a highly selective off-on fluorescent probe, is designed for the specific imaging of thioredoxin reductase (TrxR) in living cells, exhibiting its maximum absorbance at approximately 373 nm [1]. Target: Others. Smiles: N(C(OC1CSSC1)=O)C=2C3=C4C(C(=O)N(CCCC)C(=O)C4=CC=C3)=CC2
| MW: | 416.51 D |
201.00€
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PF-06456384 trihydrochloride
Item number: TGM-T73846-100mg
Description: PF-06456384 trihydrochloride is a highly efficient and selective NaV1.7 inhibitor (IC50 = 0.01 nM), acting through protein-ligand binding rather than inhibiting the associated sodium channel. It is specifically designed for intravenous infusion and can be used in pain research. Target: Sodium Channel....
| Keywords: | PF06456384 trihydrochloride |
| MW: | 829.18 D |
From 34.00€
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(S)-3-AMino-2-Methylpropanoic acid-HCl
Item number: TGM-T7401-100mg
Description: (S)-3-AMino-2-Methylpropanoic acid-HCl is an amino acid derivative that can be an agonist of the excitatory neurotransmitter glutamate and affect the nervous system. Target: Others. Smiles: Cl.C[C@@H](CN)C(O)=O
| MW: | 139.58 D |
29.00€
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Cy5 maleimide
Item number: TGM-T74120-10mg
Description: Cy5 maleimide (Cyanine5 maleimide) is a highly sensitive anatase dye for the detection of free thiols in natural protein extracts. Target: Autophagy. Smiles: [Cl-].O=C1C=CC(=O)N1CCNC(=O)CCCCCN2C=3C=CC=CC3C(C2=CC=CC=CC4=[N+](C=5C=CC=CC5C4(C)C)C)(C)C. References: Shindy, H. A. (2017). Fundamentals in the...
| Keywords: | Cyanine 5 maleimide |
| MW: | 641.24 D |
From 52.00€
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