Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Pasotuxizumab
Item number: TGM-T77130-10mg
Description: Pasotuxizumab (BAY 2010112) is a bispecific T-cell engager (BiTE) targeting PSMA and CD3, with dissociation constants (K D) of 47.0 nM for PSMA and 9.4 nM for CD3. It is used in the study of metastatic castration-resistant prostate cancer (mCRPC) [1] [2]. Target: Integrin
From 352.00€
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Rafivirumab
Item number: TGM-T77137-10mg
Description: Rafivirumab (CR57) is a monoclonal antibody targeting the rabies virus G protein, used in the study of rabies virus infection. Target: Others. References: Huang F, et al. Preexposure and Postexposure Prophylaxis of Rabies With Adeno-Associated Virus Expressing Virus-Neutralizing Antibody in Rodent...
| Keywords: | CR57 , CR 57 |
From 215.00€
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Retifanlimab
Item number: TGM-T77180-10mg
Description: Retifanlimab (MGA-012) is a monoclonal antibody targeting programmed cell death protein 1 (PD-1). Retifanlimab is used in studies of Merkel cell carcinoma. Target: PD-1/PD-L1. References: Berton D, et al. Antitumor activity and safety of the PD-1 inhibitor retifanlimab in patients with recurrent...
| Keywords: | AEX-1188 , INCMGA-0012 , MGA012 , AEX1188 , INCMGA0012 , MGA-012 |
From 233.00€
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2-Benzimidazolebutyricacid,1-methyl-(8CI)
Item number: TGM-T7719-10mg
Description: 2-Benzimidazolebutyricacid,1-methyl-(8CI), with CAS No. 802044-51-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Benzimidazolebutyricacid,1-methyl-(8CI) provides a structural basis and research tool for the design and screening of...
| MW: | 218.26 D |
From 34.00€
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Crovalimab
Item number: TGM-T77190-10mg
Description: Crovalimab (SKY59, RO7112689) is an Fc-engineered and pH-dependent humanised monoclonal antibody that binds to complement C5 and blocks its cleavage into C5a and C5b, thereby inhibiting MAC formation and intravascular haemolysis. It can rebind to the FcRn receptor under acidic pH conditions and return...
| Keywords: | SKY59 , SKY 59 , RO7112689 , RO 7112689 |
From 233.00€
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Fumaric acid disodium
Item number: TGM-T77205-25g
Description: Fumaric acid disodium is a dicarboxylic acid compound, widely applied in biochemical experiments and drug synthesis research. Target: Endogenous Metabolite, Others. Smiles: [O-]C(/C=C/C([O-])=O)=O.[Na+].[Na+]
| MW: | 160.04 D |
29.00€
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Methylene Violet 3RAX
Item number: TGM-T77235-100mg
Description: Methylene Violet 3RAX is a cationic dye, a potential photosensitizer in photodynamic therapy, with antitumor activity that alters the molecular structure of DNA, disrupts the modules of DNA, and induces the production of reactive monoclinic oxygen species, which are used to stain the mitochondria of...
| MW: | 378.9 D |
29.00€
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DSPE-PEG-Azide (MW 2000)
Item number: TGM-T77273-100mg
Description: DSPE-PEG-Azide (MW 2000) has an amphiphilic structure and can form lipid bilayers/micelles in water. It can be used to prepare nanoparticles or liposomes as targeted drug carriers. Target: Liposome. Smiles: #N/A. References: Warren MR, et al. Milk exosomes with enhanced mucus penetrability for oral...
| Keywords: | DSPE-PEG(2000) Azide |
| MW: | 2000 D |
From 38.00€
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DSPE-Biotin
Item number: TGM-T77279-10mg
Description: DSPE-Biotin is a lipid . DSPE-Biotin can be used for the research of various biochemical [1] . Target: Others. Smiles: CCCCCCCCCC CCCCCCCC(O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)(O)=O)=O
| MW: | 974.361 D |
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KKII5
Item number: TGM-T77288-200mg
Description: KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 µM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons. Target: Lipoxygenase. Smiles: S=C1NC(C=C(N1)c1ccccc1)c1ccccc1. References: Georgiou N, et al....
| MW: | 266.36 D |
From 30.00€
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Dapirolizumab
Item number: TGM-T77363-10mg
Description: Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases. Target: TNF. References: Acharya C, et al. Population Pharmacokinetics and Exposure-Response for Dapirolizumab Pegol From a Phase 2b Trial in Patients With Systemic...
| MW: | 145.5 kD |
From 313.00€
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Vonlerizumab
Item number: TGM-T77368-10mg
Description: Vonlerizumab (Anti-TNFRSF4/OX40/CD134 Antibody) is a humanized monoclonal antibody targeting OX40, used in tumor research. Target: TNF, Immunology/Inflammation related. References: Marin-Acevedo JA, et al. Next generation of immune checkpoint therapy in cancer: new developments and challenges. J...
| Keywords: | Anti-TNFRSF4/OX40/CD134 Antibody |
| MW: | 145.5 kD |
From 422.00€
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