Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Tixagevimab
Item number: TGM-T76976-10mg
Description: Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors. Target: SARS-CoV. References: Dong J, et al. Genetic and structural basis for...
| Keywords: | AZD 8895 , AZD8895 |
From 233.00€
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Tarcocimab
Item number: TGM-T76987-10mg
Description: Tarcocimab (OG1953), a humanized IgG1-type anti-VEGFA monoclonal antibody, is utilized in research targeting conditions such as retinal vein occlusion (RVO) and wet age-related macular degeneration (AMD). Target: VEGFR
From 274.00€
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Cilgavimab
Item number: TGM-T76999-10mg
Description: Cilgavimab (AZD-1061) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, used in studies of COVID-19 infection. Target: SARS-CoV. References: Zost SJ, et al. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. 2020 Aug,584(7821):443-449.
| Keywords: | AZD-1061 , AZD5156 , AZD 5156 , COV2-2130 , COV22130 , AZD1061 |
From 233.00€
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Boc-NH-PEG3
Item number: TGM-T7701-200mg
Description: Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker. Target: PROTAC Linker. Smiles: C(NCCOCCOCCO)(OC(C)(C)C)=O. References: Sainan, An, Liwu, et al. Small-molecule PROTACs: An emerging and promising approach for the...
| Keywords: | PROTAC Linker 10 |
| MW: | 249.3 D |
29.00€
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Frexalimab
Item number: TGM-T77013-10mg
Description: Frexalimab (SAR441344, INX-021), a monoclonal antibody that targets the CD40 ligand (CD40L), shows promise for research in multiple sclerosis [1]. Target: TNF
From 313.00€
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Geptanolimab
Item number: TGM-T77023-10mg
Description: Geptanolimab (CBT-501) is a humanized IgG4kappa monoclonal antibody directed against PD-1 (Programmed Death-1). Geptanolimab functions by competitively blocking the binding of PD-L1 and PD-L2 to PD-1, thereby reactivating T cell activity. Geptanolimab is under development as an immunotherapeutic agent...
| Keywords: | APL-501 , APL501 , CBT-501 , GB-226 , Genolimzumab , CBT501 |
From 187.00€
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Gontivimab
Item number: TGM-T77027-10mg
Description: Gontivimab (ALX-0171) is a trivalent nanobody targeting the hRSV fusion (F) protein with anti-RSV antiviral properties for the study of respiratory syncytial virus infections. Target: RSV. References: Detalle L, et al. Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for...
| Keywords: | VR-465 , ALX-0171 , VR465 , ALX0171 |
From 183.00€
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Gosuranemab
Item number: TGM-T77028-10mg
Description: Gosuranemab (BMS-986168), a humanized IgG4 anti-tau monoclonal antibody, specifically targets human N-terminal tau residues 15-22. It holds potential for Alzheimer's disease (AD) research [1] [2]. Target: Microtubule Associated
From 274.00€
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Insulin efsitora alfa
Item number: TGM-T77037-1mg
Description: Insulin efsitora alfa (LY-3209590) is a selective insulin receptor (IR) agonist and fusion protein that combines a novel single-chain insulin variant with the structural domain of human IgG Fc for the study of type 2 diabetes. Target: IGF-1R. References: Moyers JS, et al. Preclinical Characterization of...
| Keywords: | LY3209590 , LY-3209590 |
404.00€
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Izalontamab
Item number: TGM-T77047-10mg
Description: Izalontamab (SI-B001), a bispecific monoclonal antibody with high selectivity for the EGFR/HER3 heterodimer, targets both EGFR and HER3 receptors. It holds potential for use in cancer research [1]. Target: EGFR
From 509.00€
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Libivirumab
Item number: TGM-T77063-10mg
Description: Libivirumab (17.1.41), a humanized monoclonal antibody targeting hepatitis B virus (HBV), demonstrates neutralizing activity with half maximal inhibitory concentrations (IC50) of 35 ng/mL for HBsAg and 130 ng/mL for HBeAg, respectively [1]. Target: HBV
From 233.00€
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Licaminlimab
Item number: TGM-T77064-10mg
Description: Licaminlimab (OCS-02) is a single-chain anti-TNF alpha antibody fragment targeting TNF alpha, an inflammatory cytokine produced by macrophages and monocytes during inflammation [1]. Target: TNF
From 233.00€
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