Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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L-beta-Imidazolelactic acid
L-beta-Imidazolelactic acid

Item number: TGM-T201443-10mg

Description: L-beta-Imidazolelactic acid, a histidine derivative and oxidizing agent, induces antioxidant effects in the rat cerebral cortex. Smiles: C([C@@H](C(O)=O)O)C1=CN=CN1
MW: 156.14 D
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Review
p62-ZZ Ligand-Linker Conjugate 1
p62-ZZ Ligand-Linker Conjugate 1

Item number: TGM-T201445-10mg

Description: p62-ZZ Ligand-Linker Conjugate 1 is a conjugate of the p62-ZZ domain ligand and linker. This compound is utilized in the synthesis of AUTOTACVinclozolinM2-2204. Target: Autophagy. Smiles: O(CCC1=CC=CC=C1)C2=C(OCCC3=CC=CC=C3)C=CC(OC[C@@H](CNCCOCCOCCN)O)=C2
MW: 538.68 D
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PKR1 antagonist 1
PKR1 antagonist 1

Item number: TGM-T201456-10mg

Description: PKR1 antagonist 1 (PC1) is an effective antagonist of PKR1. It alleviates both hyperalgesia and allodynia in SNI mice. Smiles: O=C1N=C(NCCNC(=N)N)N(C(=O)N1CC2=CC=C(C=C2)CC)CC3=CC=C(OC)C=C3
MW: 451.52 D
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Review
ATM Inhibitor-11
ATM Inhibitor-11

Item number: TGM-T201457-10mg

Description: ATMInhibitor-11 (Compound 1) is an inhibitor of ATM with an IC50 of 0.32 nM. It also inhibits KAP1 phosphorylation with an IC50 of 0.97 nM. This compound exhibits high exposure in the brain, heart, and plasma of ICR mice. Furthermore, ATMInhibitor-11 demonstrates antitumor activity in the NCI-H441...
MW: 492.59 D
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Review
3D-Monophosphoryl Lipid (14) triethylamine
3D-Monophosphoryl Lipid (14) triethylamine

Item number: TGM-T201459-10mg

Description: 3D-Monophosphoryl Lipid (14) (3D-Monophosphoryl Lipid (14)) triethylamine is a TLR agonist that serves as an adjuvant in vaccines to enhance their immunogenicity. Smiles: N(CC)(CC)CC.O(C(C[C@H](OC(CCCCCCCCCC...
Keywords: 3D-MPL (14) triethylamine
MW: 1831.63 D
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E3 Ligase Ligand-linker Conjugate 132
E3 Ligase Ligand-linker Conjugate 132

Item number: TGM-T201463-10mg

Description: E3 Ligase Ligand-linker Conjugate 133 is a critical intermediate in the synthesis of the complete PROTAC molecule CPD-39, comprising a conjugate (conjugate of E3 ligase Ligand and linker) that connects the E3 ligase ligand with a linker. Smiles: O=C(NC1=NN=C(C=C1)N(C)C)C2=CC=C(N=C2NC3CC4(CC(N)C4)C3)NC
MW: 396.49 D
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Review
LU 2443
LU 2443

Item number: TGM-T201466-10mg

Description: LU 2443 is an orally active antiepileptic agent that is extensively absorbed, with up to 18% remaining unabsorbed in rats. The active half-life in plasma is 13.17 hours. Target: Drug Metabolite. Smiles: S=C1[N-][N+](=C(S1)C=2C=CC=CC2)C
MW: 208.3 D
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Review
NLRP3-IN-57
NLRP3-IN-57

Item number: TGM-T201467-10mg

Description: NLRP3-IN-57 (compound 5) inhibits the NLRP3 inflammasome, consequently downregulating IL-1beta levels in THP-1 macrophages induced by LPS+Nigericin. Target: NOD-like Receptor (NLR). Smiles:...
MW: 700.94 D
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Review
Monophosphoryl lipid A free acid
Monophosphoryl lipid A free acid

Item number: TGM-T201469-10mg

Description: Monophosphoryl lipid A (free acid) acts as an agonist for toll-like receptor 4. It is employed in immunological and vaccine research. Smiles: N(C(C[C@H](OC(CCCCCCCCCC...
Keywords: Glucopyranosyl lipid A free acid
MW: 1746.44 D
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Review
Bensuldazic acid sodium
Bensuldazic acid sodium

Item number: TGM-T201473-10mg

Description: Bensuldazic acid sodium (compound 4f) is a lipophilic 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione (THTT) derivative, which serves as a prodrug model. Additionally, Bensuldazic acid exhibits antifungal activity. Smiles: O=C(CN1CSC(N(C1)CC2=CC=CC=C2)=S)[O-].[Na+]
MW: 304.36 D
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Review
DNA crosslinker 6
DNA crosslinker 6

Item number: TGM-T201475-10mg

Description: DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM. Target: Parasite. Smiles:...
MW: 363.42 D
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Review
1'-Naphthoyl-2-methylindole
1'-Naphthoyl-2-methylindole

Item number: TGM-T201477-10mg

Description: 1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 µM. Target: Cannabinoid Receptor. Smiles: O=C(C1=CC=CC=2C=CC=CC21)C=3C=4C=CC=CC4NC3C
MW: 285.34 D
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21 from 12274 pages