Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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JFX 650, NHS ester
Item number: TGM-T201379-100mg
Description: JFX 650, NHS ester, a deuterated red fluorescent Janelia Fluor(R) dye, is provided with an NHS ester reactive group for labeling primary amines. It is ideal for live cell imaging. Target: Others. Smiles:...
| MW: | 637.85 D |
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Janelia Fluor 549, Haloalkane
Item number: TGM-T201381-100mg
Description: Janelia Fluor 549, Haloalkane, a yellow cell-permeable fluorogenic fluorescent dye featuring a chloroalkane handle, exhibits a high level of fluorogenicity. The compound's excitation and emission maxima (lambda) are respectively 549 nm and 571 nm, with a quantum yield = 0.88. Target: Others. Smiles:...
| MW: | 660.2 D |
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Janelia Fluor 646, Haloalkane
Item number: TGM-T201384-100mg
Description: Janelia Fluor 646, Haloalkane, a red cell-permeable fluorogenic fluorescent dye featuring a chloroalkane handle, exhibits significant fluorogenicity. The excitation and emission maxima (lambda) for this compound are 646 nm and 664 nm, respectively, with a quantum yield of 0.54. Target: Others. Smiles:...
| MW: | 702.35 D |
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SIRT3 activator 1
Item number: TGM-T201386-100mg
Description: SIRT3 Activator 1 (Compound 5v) is a selective activator of SIRT3. It enhances the expression of SIRT3, leading to upregulation of SOD2 and OPA1. This activity effectively mitigates mitochondrial dysfunction, alleviates oxidative stress, and maintains the vitality of cardiac myocytes. SIRT3 Activator 1...
| MW: | 556.67 D |
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PDE9-IN-2
Item number: TGM-T201403-10mg
Description: PDE9-IN-2 (compound 6) is a PDE9 inhibitor that enhances heart failure management. Smiles: O=C(O)C=1SC=2NC(=NC(=O)C2C1C)CC3=CC=C(Cl)C(Cl)=C3
| MW: | 369.22 D |
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Glutaminyl cyclases-IN-2
Item number: TGM-T201406-10mg
Description: Glutaminyl cyclases-IN-2 (compound 27) serves as a potent inhibitor of glutaminyl cyclase, displaying an IC50 value of 0.08 µM. This compound plays a crucial role in cancer research. Smiles: COC1=C(OC)C(OC)=CC(C2=CC=CC=C2NCCCN3C=NC=C3C)=C1
| MW: | 381.47 D |
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TRIB2 ligand-1
Item number: TGM-T201407-10mg
Description: TRIB2 ligand-1 is a ligand for TRIB2 (Ligands for Target Protein for PROTACs). This compound serves as a precursor for the synthesis of PROTAC TRIB2 degrader-1. Target: Ligands for Target Protein for PROTAC. Smiles: O=C(NC1=CC=C2C(=C1)CNCC2)C3=NNC4=CC=C(C=C34)C=5C=CC=NC5F
| MW: | 387.41 D |
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Sitamaquine hydrochloride
Item number: TGM-T201411-10mg
Description: Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of...
| Keywords: | WR 6026 hydrochloride |
| MW: | 416.43 D |
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DL-2-Aminopimelic Acid
Item number: TGM-T201414-10mg
Description: DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate. Target: Others. Smiles: O=C(O)CCCCC(N)C(=O)O
| MW: | 175.18 D |
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JH-LPH-107
Item number: TGM-T201428-10mg
Description: JH-LPH-107, an LpxH inhibitor, exhibits a low spontaneous resistance rate and a high safety margin in vitro. Smiles: O=C(NC1=CC=C(C=C1)S(=O)(=O)N2CCN(C3=NC(Cl)=CC(=C3)C(F)(F)F)CC2)C=4C=CC=CC4N(C)S(=O)(=O)C
| MW: | 632.08 D |
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HSP90-IN-35
Item number: TGM-T201430-10mg
Description: HSP90-IN-35 is an inhibitor targeting Hsp90, exhibiting anticancer activity. It demonstrates an IC50 ranging from 0.05 to 0.5 µM against Her2. Additionally, HSP90-IN-35 can be utilized in the synthesis of PROTAC. Target: Ligands for Target Protein for PROTAC, HSP. Smiles:...
| MW: | 507.58 D |
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Erizepine
Item number: TGM-T201442-10mg
Description: Erizepine, an octopamine receptor 3 (OAR3) antagonist, exhibits a Ki value of 474 nM. This compound is utilized in insect research. Target: Others. Smiles: C1=CC=C2C(=C1)C3=C(C=4C=CC=CC4N2C)CCN(C)CC3
| Keywords: | Eresepine |
| MW: | 290.4 D |
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