Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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N3-D-Orn(Boc)-OH
Item number: TGM-T87938-100mg
Description: N3-D-Orn(Boc)-OH, a Boc-protected pentanoic amino acid derivative, serves as a click chemistry reagent and has been utilized in the synthesis of antibody-drug conjugates (ADC) [1]. Target: ADC Linker. Smiles: [C@H](CCCNC(OC(C)(C)C)=O)(N=[N+]=[N-])C(O)=O
| MW: | 258.27 D |
From 1,440.00€
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BDW-OH
Item number: TGM-T87958-100mg
Description: BDW-OH is an active metabolite of the STING agonist and prodrug BDW568. Smiles: O=C(O)CSC1=NN=C2C3=C(N=CN12)SC(=C3C)C
| MW: | 294.4 D |
From 1,440.00€
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sGC activator 1
Item number: TGM-T87987-100mg
Description: sGC Activator 1 (example 10B) serves as an activator for soluble guanylate cyclase (sGC). Target: Liposome. Smiles: C[C@@]1(C=2C(NC1=O)=NC(=NC2N)C=3C=4C(N(CCC(C(F)(F)F)(F)F)N3)=CC(Cl)=CC4)C5=CC=C(CCC(O)=O)C=C5
| MW: | 608.95 D |
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alpha-Synuclein aggregate binder 1
Item number: TGM-T87988-100mg
Description: alpha-Synucleinaggregate binder 1 (Compound C05-05) is a collective binding agent and an inhibitor of alpha-synuclein aggregation. It is applicable in positron emission tomography (PET) imaging and fluorescence microscopy, aiding in the diagnosis and treatment of neurodegenerative diseases. Target:...
| MW: | 383.44 D |
From 1,830.00€
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Tolmesoxide
Item number: TGM-T87991-100mg
Description: Tolmesoxide (RX71107), a peripheral vascular dilator, exhibits blood pressure-lowering actions by promoting direct vasodilation in the human forearm arterial bed and the dorsal hand vein. It can increase blood flow in the forearm and induce dilation in contracting dorsal hand veins in a dose-dependent...
| Keywords: | RX71107 |
| MW: | 214.28 D |
From 1,440.00€
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Colterol acetate
Item number: TGM-T87993-100mg
Description: Colterol acetate is a selective beta-adrenergic receptor inhibitor that relaxes tracheal smooth muscle primarily through beta2 receptors, reduces subspastic contractions of tricholoma (acting on beta2), and enhances the contractility of left ventricular papillary muscles by targeting beta1 receptors....
| MW: | 285.34 D |
From 1,440.00€
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Mcl-1 inhibitor 10
Item number: TGM-T87994-100mg
Description: Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 µM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers....
| MW: | 388.34 D |
From 1,440.00€
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BC-1901S
Item number: TGM-T87995-100mg
Description: BC-1901S functions as a proteasome-independent activator and stabilizer of NRF2. By binding to DCAF1 (E3 ligase subunit), it disrupts the NRF2/DCAF1 interaction and activates NRF2 through the inhibition of NRF2 ubiquitination, independent of KEAP1. BC-1901S has demonstrated anti-inflammatory effects in...
| MW: | 424.9 D |
From 1,440.00€
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Anemoside A3-methyl 6-aminohexanoate
Item number: TGM-T87999-10mg
Description: Anemoside A3-methyl 6-aminohexanoate (Compound A3-6), a derivative of Pulchinenoside C (Anemoside B4), exhibits potent inhibition of pyruvate carboxylase (PC) with an IC 50 of 0.058 µM. It also reprograms macrophage function and alleviates DSS-induced colitis by inhibiting the NF-kappaB and NLRP3...
| MW: | 878.14 D |
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MicroRNA modulator-1
Item number: TGM-T88000-100mg
Description: MicroRNAmodulator-1 (TABLE4 compound 1) is an oxadiazole-class inhibitor of miR-21 with an AC50 of 14.64 µM. Target: MicroRNA. Smiles: O=C(C=CC1=CC=C(OC)C(=C1)S(=O)(=O)N2CCOCC2)NC3CCCCCC3
| MW: | 422.54 D |
From 1,440.00€
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pan-KRAS-IN-6
Item number: TGM-T88001-100mg
Description: Pan-KRAS-IN-6 (compound 12) is a potent pan-KRAS inhibitor, with IC50 values of 9.79 nM for Kras G12D and 6.03 nM for Kras G12V. Target: Kras, Ras. Smiles: C(OC=1N=C(C2=C(N1)C(F)=C(C(Cl)=C2)C3=C4C(SC(N)=N4)=C(F)C=C3)N5CC(C)(O)COCC5)[C@@]67N(C[C@H](F)C6)CCC7
| MW: | 635.1 D |
From 2,010.00€
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Anticancer agent 218
Item number: TGM-T88002-100mg
Description: Anticancer agent 218 (P136) is a camptothecin-related compound with anticancer properties. Target: Topoisomerase. Smiles: [C@@H](C)(N)C1=C2C(C=3N(C2)C(=O)C4=C(C3)[C@](CC)(O)C(=O)OC4)=NC=5C1=CC6=C(C5)OC(F)(F)O6
| MW: | 471.41 D |
From 1,583.00€
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