Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Cabergoline
Item number: TGM-T14853-1mg
Description: Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels....
| Keywords: | FCE-21336 |
| Application: | Targets dopamine receptor D2 (DRD2) |
| CAS | 81409-90-7 |
| MW: | 451.6 D |
From 33.00€
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Nitrosoglutathione
Item number: TGM-T19930-50mg
Description: Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, inhibits cerebral angiotensin II-dependent and -independent AT1 receptor responses....
| Keywords: | GSNO, SNOG, S-Nitrosoglutathione, Glutathione thionitrite |
| CAS | 57564-91-7 |
| MW: | 336.32 D |
From 46.00€
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Ginsenoside Rg1
Item number: TGM-T2777-100mg
Description: Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal synaptophysin level in mice, plus demonstrates estrogen-like activity. Target: Apoptosis, Beta Amyloid,...
| Keywords: | Panaxoside A, Ginsenoside A2, Sanchinoside C1, Panaxoside Rg1, Sanchinoside Rg1 |
| CAS | 22427-39-0 |
| MW: | 801.01 D |
From 48.00€
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Ginsenoside Rb1
Item number: TGM-T2822-100mg
Description: Ginsenoside Rb1 (Gypenoside III) is part of a class of steroid glycosides, may have properties that inhibit or prevent the growth of tumors. Target: ATPase, Autophagy, Mitophagy, IRAK, HSV, NF-kappaB. Smiles:...
| Keywords: | Gypenoside III, Gypenoside III |
| CAS | 41753-43-9 |
| MW: | 1109.29 D |
From 38.00€
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WSP-1
Item number: TGM-T36511-1mg
Description: WSP-1 is a selective 2-pyridyl disulfide fluorescent probe for hydrogen sulfide detection and bioimaging. Smiles: O=C(OC1=CC=C2C(OC3=CC(OC)=CC=C3C42OC(=O)C=5C=CC=CC54)=C1)C=6C=CC=CC6SSC7=NC=CC=C7. References: Martelli A, et al. Vascular Effects of H2S-Donors: Fluorimetric Detection of H2S Generation and...
| CAS | 1352750-34-5 |
| MW: | 591.65 D |
From 55.00€
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DMAPP triammonium
Item number: TGM-T38570-1mg
Description: DMAPP triammonium (Dimethylallyl diphosphate triammonium) is one of the prerequisite substances for an isoprenoid involved in the mevalonate (MVA) pathway, which can be used in the study of metabolism-related diseases. Target: Others. Smiles: O=P([O-])(OP([O-])(OC/C=C(C)/C)=O)[O-].[NH4+].[NH4+].[NH4+]
| Keywords: | Dimethylallyl diphosphate triammonium , Dimethylallyl Pyrophosphate triammonium salt |
| CAS | 1186-30-7 |
| MW: | 297.18 D |
From 233.00€
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Penicillide
Item number: TGM-T36931-1mg
Description: Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities. It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM) and acyl-coenzyme A:cholesterol acyltransferase (ACAT, IC50 = 22.9 µM). It is also an antagonist of oxytocin receptors (IC50 = 67 µM)....
| Application: | ACAT Inhibitor |
| CAS | 55303-92-9 |
| MW: | 372.417 D |
From 255.00€
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Daminozide
Item number: TGM-T3719-1mL
Description: Daminozide (Succinic Acid) is a plant growth regulator, selectively inhibits the KDM2/7 JmjC subfamily. Target: Histone Demethylase. Smiles: CN(C)NC(=O)CCC(O)=O. References: Reed DJ, Moore TC, Anderson JD. Science. 1965 Jun 11,148(3676):1469-71.
| Keywords: | Succinic Acid, Aminozide, DMASA |
| Application: | Demethylase inhibitor |
| CAS | 1596-84-5 |
| MW: | 160.17 D |
From 40.00€
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Glycyl-L-Histidyl-L-Lysine
Item number: TGM-T4508-1g
Description: Glycyl-L-histidyl-L-lysine is a synthetic hepatotrophic agent and liver cell growth factor that stimulates the production of hepatic erythropoietic factor. Target: Others. Smiles: [C@H](CC1=CN=CN1)(C(N[C@@H](CCCCN)C(O)=O)=O)NC(CN)=O. References: Naughton BA,etal.The influence of pancreatic hormones and...
| CAS | 49557-75-7 |
| MW: | 340.38 D |
From 29.00€
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Talazoparib
Item number: TGM-T6253-2mg
Description: Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM). Target: PARP. Smiles: Cn1ncnc1[C@@H]1[C@H](Nc2cc(F)cc3c2c1n[nH]c3=O)c1ccc(F)cc1. References: Wilkerson PM, et al. Preclinical evaluation of the PARP inhibitor BMN-673 for the treatment of...
| Keywords: | LT-673, BMN-673 |
| Application: | Targets poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] (PARP1) |
| CAS | 1207456-01-6 |
| MW: | 380.35 D |
From 34.00€
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Romidepsin
Item number: TGM-T6006-1mg
Description: Romidepsin (FR 901228) is an HDAC inhibitor that inhibits HDAC1/2/4/6 (IC50=36/47/510/1400 nM). Romidepsin has antitumor activity and can be used for the treatment of peripheral T-cell lymphoma and cutaneous T-cell lymphoma. Target: Apoptosis, HDAC. Smiles:...
| Keywords: | FR 901228 , FK 228 , Depsipeptide , NSC 630176 |
| Application: | Antineoplastic, Histone deacetylase inhibitor |
| CAS | 128517-07-7 |
| MW: | 540.7 D |
From 87.00€
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Vinorelbine ditartrate
Item number: TGM-T6213-5mg
Description: Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor activity, inhibiting cell proliferation and inducing apoptosis. Target: Microtubule Associated, Autophagy. Smiles:...
| Keywords: | Nor-5'-anhydrovinblastine ditartrate, Vinorelbine Tartrate, KW-2307, Navelbine tartrate |
| Application: | Targets tubulin beta (TUBB) |
| CAS | 125317-39-7 |
| MW: | 1079.11 D |
From 30.00€
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