Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Avibactam sodium dihydrate
Item number: TGM-T60874-100mg
Description: Avibactam sodium (NXL-104) dihydrate inhibits CTX-M-15 and beta-lactamase TEM-1 with IC50 values of 5 nM and 8 nM, respectively, and is a reversible covalent inhibitor of non-beta-lactam beta-lactamase [1]. Target: Others
| MW: | 323.26 D |
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5-Ph-IAA-AM
Item number: TGM-T60878-10mg
Description: 5-Ph-IAA-AM, an eggshell-permeable analog of 5-Ph-IAA, enhances protein degradation in laid embryos and can be used to reveal the roles of temporally controlled protein degradation in C. elegans embryogenesis and development [1]. Target: Others
| MW: | 323.34 D |
From 840.00€
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MLKL-IN-1
Item number: TGM-T60885-100mg
Description: MLKL-IN-1, a covalent inhibitor of MLKL, has a dissociation constant (Kd) of 50 µM. Target: Others
| MW: | 324.37 D |
From 1,440.00€
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NiCur
Item number: TGM-T60888-100mg
Description: NiCur blocks CBP HAT activity and downregulates p53 activation upon genotoxic stress. NiCur is a potent and selective inhibitor of CBP histone acetyltransferase (HAT) with an IC 50 value of 0.35 µ?. NiCur can be used to perform mechanistic studies without affecting target proteins expression [1]....
| MW: | 324.38 D |
From 585.00€
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JAK-2/3-IN-3
Item number: TGM-T60895-100mg
Description: JAK-2-/3-IN-3 (compound ST4j) is a potent inhibitor of JAK2/3, with IC50 values of 13.00 and 14.86 nM for JAK2 and JAK3, respectively. It inhibits JAK2 autophosphorylation, induces apoptosis in a time- and dose-dependent manner, and can be used in lymph-derived diseases and leukemia research [1]....
| MW: | 325.15 D |
From 1,440.00€
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HER2-IN-11
Item number: TGM-T60896-100mg
Description: HER2-IN-11 is a psoralen derivative that induces apoptosis, exhibits light-activated cytotoxicity, and demonstrates anti-breast cancer activity [1]. Target: Others
| MW: | 325.27 D |
From 1,440.00€
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HbF inducer-1
Item number: TGM-T60898-100mg
Description: HbF inducer-1 is a fetal hemoglobin inducer which is orally bioavailable. Target: Others
| MW: | 325.36 D |
From 1,440.00€
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IRAK4-IN-11
Item number: TGM-T60899-100mg
Description: IRAK4-IN-11 (compound 6) is a potent IRAK4 inhibitor with an IC50 of 0.008 µM, demonstrating cell pIRAK4 potencies with an IC50 of 0.19 µM [1]. Target: Others
| MW: | 325.37 D |
From 1,440.00€
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Miaosporone A
Item number: TGM-T60906-100mg
Description: Miaosporone A is an angucyclic quinone which shows cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells. Miaosporone A has antibacterial activity against Mycobacterium tuberculosis and antimalarial activity against Plasmodium falciparum K1 with IC50 values of...
| MW: | 326.34 D |
From 1,440.00€
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EGFR/HER2-IN-8
Item number: TGM-T60938-100mg
Description: EGFR/HER2-IN-8 (compound 34) is an inhibitor of EGFR, HER2, and DHFR with IC50 values of 0.45 µM, 0.244 µM, and 5.669 µM, respectively. It demonstrates anticancer activity against several cancer cell lines, exhibiting a high safety profile and selectivity indices, making it useful for cancer research...
| MW: | 328.39 D |
From 1,440.00€
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ChE/Abeta1-42-IN-1
Item number: TGM-T60940-100mg
Description: ChE/Abeta1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Abeta1-42 with excellent BBB permeability, exhibiting IC50 values of 0.062 µM for AChE, 0.767 µM for BuChE, and 1.227 µM for Abeta1-42 aggregation. ChE/Abeta1-42-IN-1 is a potent multi-targeted anti-Alzheimer's disease agent...
| MW: | 328.41 D |
From 1,440.00€
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LSD1-IN-15
Item number: TGM-T60941-100mg
Description: LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor that inhibits LSD1-CoREST, MAO-A, and MAO-B with IC50 values of 0.149, 0.028, and 0.327 µM, respectively. LSD1-IN-15 induces cell growth arrest in LNCaP cells of prostate cancer, with an IC50 value of 9.9 µM [1]. Target: Others
| MW: | 328.41 D |
From 1,440.00€
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