Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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5-HT7R antagonist 1
5-HT7R antagonist 1

Item number: TGM-T60790-100mg

Description: 5-HT7R antagonist 1 is a G protein-biased antagonist with a Ki of 6.5 nM for 5-HT7R. Target: Others
MW: 313.23 D
From 1,440.00€ *
Review
Antitubercular agent-11
Antitubercular agent-11

Item number: TGM-T60791-100mg

Description: Antitubercular agent-11 (Compound 1e) contains a bulkier electron-donating group (Bu-t) and exhibits the best MIC value of 0.060 µg/mL [1]. Target: Others
MW: 313.31 D
From 1,440.00€ *
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NMDA receptor antagonist-3
NMDA receptor antagonist-3

Item number: TGM-T60792-100mg

Description: NMDA receptor antagonist-3 is a NMDA receptor antagonist with a significan recovery rate (40.0%, at 100 µM) and safe toxicological characteristics in SH-SY5Y and human adipose mesenchymal stem cells. Target: Others
MW: 313.31 D
From 1,440.00€ *
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HDAC10-IN-1
HDAC10-IN-1

Item number: TGM-T60794-100mg

Description: HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor (IC50 = 58 nM) that regulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1]. Target: Others
MW: 313.39 D
From 903.00€ *
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Monoamine Oxidase B inhibitor 2
Monoamine Oxidase B inhibitor 2

Item number: TGM-T60806-100mg

Description: Monoamine Oxidase B inhibitor 2 is a potent, reversible, orally active, and selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 1.33 nM, capable of crossing the blood-brain barrier (BBB). It exhibits antioxidant and anti-neuroinflammatory activities and is useful in the study of...
MW: 314.35 D
From 1,440.00€ *
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AChE/BChE-IN-3 hydrochloride
AChE/BChE-IN-3 hydrochloride

Item number: TGM-T60831-100mg

Description: AChE/BChE-IN-3 (BMC-1) hydrochloride is a dual inhibitor of AChE and BChE, with IC50 values of 0.383 µM against equine serum BChE (eqBChE) and 6.08 µM against electric eel AChE (elAChE) [1]. Target: Others
MW: 316.82 D
From 1,440.00€ *
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SARS-CoV-2-IN-23
SARS-CoV-2-IN-23

Item number: TGM-T60841-100mg

Description: SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.3 µM [1]. Target: Others
MW: 318.41 D
From 1,440.00€ *
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GABAA receptor agonist 1
GABAA receptor agonist 1

Item number: TGM-T60842-100mg

Description: GABAA receptor agonist 1 (compound 3e) is a potent agonist that binds to the GABA binding site of the GABAA receptor, producing GABAergic effects and exhibiting anti-depression activities in classical mouse models of FST and TST, indicating its potential in depression research [1]. Target: Others
MW: 318.45 D
From 1,440.00€ *
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Heme Oxygenase-2-IN-1
Heme Oxygenase-2-IN-1

Item number: TGM-T60847-100mg

Description: Heme Oxygenase-2-IN-1 (Compound 9) is a potent, selective inhibitor of heme oxygenase-2 (HO-2), with IC50 values of 14.9 µM for HO-1 and 0.9 µM for HO-2 [1]. Target: Others
MW: 319.36 D
From 1,440.00€ *
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Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3

Item number: TGM-T60848-100mg

Description: Carbonic anhydrase inhibitor 3 (compound 11g) is a carbonic anhydrase II inhibitor that reduces intraocular pressure in glaucomatous rabbits [1]. Target: Others
MW: 319.38 D
From 1,440.00€ *
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SARS-CoV-2 nsp3-IN-1
SARS-CoV-2 nsp3-IN-1

Item number: TGM-T60861-100mg

Description: SARS-CoV-2 nsp3-IN-1 (Compound 15c) exhibits significant selectivity for coronavirus macrodomains, particularly SARS-CoV-2 Mac1, and can inhibit Mac1 ADP-ribosylhydrolase activity with an IC50 of 6.1 µM [1]. Target: Others
MW: 321.33 D
From 1,440.00€ *
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Antibacterial agent 78
Antibacterial agent 78

Item number: TGM-T60865-100mg

Description: Antibacterial agent 78 (compound 30) is an antibacterial agent with an improved cytotoxicity profile[1]. Target: Others
MW: 321.5 D
From 1,440.00€ *
Review
12458 from 12463 pages