Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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TK-129
TK-129

Item number: TGM-T60713-100mg

Description: TK-129 is an orally active, potent inhibitor of KDM5B with an IC50 of 44 nM and is low-toxicity. TK-129 exhibits cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 can be used in cardiovascular disease studies to reduce isoprenaline-induced myocardial...
MW: 305.38 D
From 747.00€ *
Review
Prohibitin ligand 1
Prohibitin ligand 1

Item number: TGM-T60722-100mg

Description: Prohibitin ligand 1 (Compound 22i) is a cardioprotective prohibitin ligand that shows in vitro cardioprotective activities at nanomolar concentrations, inducing the pro-survival factor STAT3 phosphorylation [1]. Target: Others
MW: 306.4 D
From 1,440.00€ *
Review
URAT1 inhibitor 3
URAT1 inhibitor 3

Item number: TGM-T60724-100mg

Description: URAT1 inhibitor 3 is a potent, orally active, selective inhibitor of URAT1 (IC50 = 0.8 nM) demonstrating urate-lowering efficacy, suitable for research in gout and hyperuricemia [1]. Target: Others
MW: 307.13 D
From 1,440.00€ *
Review
TMX-4113
TMX-4113

Item number: TGM-T60740-100mg

Description: TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1alpha(CK1alpha) degrader [1]. Target: Others
MW: 308.38 D
From 1,327.00€ *
Review
HDAC10-IN-2
HDAC10-IN-2

Item number: TGM-T60760-100mg

Description: HDAC10-IN-2 (compound 10c) is a potent and highly selective HDAC10 inhibitor (IC50 = 20 nM) that regulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells [1]. Target: Others
MW: 310.39 D
From 1,440.00€ *
Review
MMG-11 quarterhydrate
MMG-11 quarterhydrate

Item number: TGM-T60763-100mg

Description: MMG-11 quarterhydrate is a potent and selective antagonist of human TLR2, inhibiting both TLR2/1 and TLR2/6 signaling with low cytotoxicity. The IC50 values for Pam3CSK4-induced hTLR2/1 and Pam2CSK4-induced hTLR2/6 responses are 1.7 µM and 5.7 µM, respectively [1]. Target: Others
MW: 310.78 D
From 1,156.00€ *
Review
COX-2/PI3K-IN-2
COX-2/PI3K-IN-2

Item number: TGM-T60769-100mg

Description: COX-2/PI3K-IN-2 (compound 5f) possesses anti-inflammatory and anti-cancer properties, functioning as a selective inhibitor of COX-2 (Ki = 3.02 nM) and a potent inhibitor of PI3K (IC50 = 2.78 nM) [1]. Target: Others
MW: 311.34 D
From 1,440.00€ *
Review
ERRgamma agonist-1
ERRgamma agonist-1

Item number: TGM-T60772-100mg

Description: ERRgamma agonist-1 can be used in neuropsychological disorders research. ERRgamma agonist-1 increases the ERRgamma transcriptional activities that is a potent agonist of ERRgamma [1]. Target: Others
MW: 311.38 D
From 1,440.00€ *
Review
Anti-Influenza agent 3
Anti-Influenza agent 3

Item number: TGM-T60778-100mg

Description: Anti-Influenza agent 3 (compound 11h) is a potent anti-influenza agent with low cytotoxicity for MDCK epithelial cells, inhibiting the M2 WT and S31N ion channel conductivity. It has an EC50 value of 3.29 µM for A/HK/68 (H3N2, M2-WT) and 2.45 µM for A/WSN/33 (H1N1, M2-S31N) strain [1]. Target: Others
MW: 311.87 D
From 1,440.00€ *
Review
CD73-IN-13
CD73-IN-13

Item number: TGM-T60779-100mg

Description: CD73-IN-13 is able to be used in a medicament preparing for tumor-related diseases. CD73-IN-13 is a potent inhibitor of CD73 which is closely associated with tumor growth, angiogenesis and metastasis [1]. Target: Others
MW: 312.25 D
From 1,440.00€ *
Review
Aurora/LIM kinase-IN-1
Aurora/LIM kinase-IN-1

Item number: TGM-T60783-100mg

Description: Aurora/LIM kinase-IN-1 (Compound F114) is a potent dual inhibitor of aurora and LIM kinases. It inhibits the proliferation and invasion of glioblastoma multiforme (GBM), making it a potential candidate for drug development in GBM and other cancers. Aurora and LIM kinases are involved in neoplastic cell...
MW: 312.37 D
From 1,440.00€ *
Review
SARS-CoV-2-IN-6
SARS-CoV-2-IN-6

Item number: TGM-T60785-100mg

Description: SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with an IC50 value of 73 nM. Target: Others
MW: 312.75 D
From 945.00€ *
Review
12457 from 12463 pages