Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

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SB 258741 hydrochloride
SB 258741 hydrochloride

Item number: TGM-T61724-100mg

Description: SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1]. Target: Others
MW: 386.98 D
From 1,440.00€ *
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VU0463271 quarterhydrate
VU0463271 quarterhydrate

Item number: TGM-T61725-100mg

Description: VU0463271 quarterhydrate is a potent KCC2 antagonist with an IC50 of 61 nM [1]. Target: Others
MW: 387 D
From 1,450.00€ *
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EGFR/HER2-IN-6
EGFR/HER2-IN-6

Item number: TGM-T61732-100mg

Description: EGFR/HER2-IN-6 (compound 43) is a dual EGFR/HER2 and DHFR inhibitor with potent activity against EGFR kinase, HER2 kinase, and DHFR, characterized by IC50 values of 0.122 µM, 0.078 µM, and 0.585 µM, respectively. This compound displays notable anticancer properties in various cancer cell lines, while...
MW: 387.46 D
From 1,440.00€ *
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Quorum Sensing-IN-1
Quorum Sensing-IN-1

Item number: TGM-T60595-100mg

Description: Quorum Sensing-IN-1 [QSI-1] is a small-molecule inhibitor targeting quorum sensing. Target: Others
MW: 290.36 D
From 1,440.00€ *
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HDAC8-IN-2
HDAC8-IN-2

Item number: TGM-T61549-100mg

Description: HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor with IC50 values of 0.27 µM and 0.32 µM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and significantly reduces egg laying in adult worm pairs [1]. Target: Others
MW: 376.36 D
From 1,440.00€ *
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Antileishmanial agent-5
Antileishmanial agent-5

Item number: TGM-T61560-100mg

Description: Antileishmanial agent-4 is a ribonucleoside analogue with potent activity against L. infantum and T. cruzi, exhibiting EC50 values of 0.68 µM and 0.83 µM, respectively [1]. Target: Others
MW: 376.79 D
From 1,440.00€ *
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VEGFR-2-IN-18
VEGFR-2-IN-18

Item number: TGM-T61561-100mg

Description: VEGFR-2-IN-18 (Compound 15d) is a high-potency inhibitor of VEGFR-2, exhibiting an IC50 value of 60 nM. This compound effectively induces cell apoptosis and demonstrates significant antitumor properties [1]. Target: Others
MW: 376.8 D
From 1,440.00€ *
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Vanin-1-IN-3
Vanin-1-IN-3

Item number: TGM-T61568-100mg

Description: Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC50 of 0.038 µM [1]. Target: Others
MW: 377.36 D
From 1,440.00€ *
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Mt KARI-IN-1
Mt KARI-IN-1

Item number: TGM-T61569-100mg

Description: Mt KARI-IN-1 is a lead compound that demonstrates strong inhibitory activity towards Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 3.06 µM [1]. Target: Others
MW: 377.4 D
From 1,440.00€ *
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MtTMPK-IN-5
MtTMPK-IN-5

Item number: TGM-T61573-100mg

Description: MtTMPK-IN-5 (compound 17) is a highly effective inhibitor of M. tuberculosis thymidylate kinase (Mtb TMPK), demonstrating remarkable enzyme inhibitory activity with an IC50 of 34 µM. Additionally, MtTMPK-IN-5 exhibits notable activity against M. tuberculosis, with an MIC of 12.5 µM. Given its potent...
MW: 377.44 D
From 1,440.00€ *
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PD-L1-IN-1
PD-L1-IN-1

Item number: TGM-T61574-100mg

Description: PD-L1-IN-1, a powerful PD-L1 inhibitor, demonstrated an IC50 of 115 nM. By forming a robust bond with the PD-L1 protein, PD-L1-IN-1 effectively suppressed tumor growth by enhancing the antitumor immune activity of peripheral blood mononuclear cells in co-cultures with PD-L1 expressing cancer cells (PC9...
MW: 377.44 D
From 815.00€ *
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LasR-IN-2
LasR-IN-2

Item number: TGM-T61581-100mg

Description: LasR-IN-2, a compound that inhibits the activity of LasR, forms hydrogen bonding with the TRY-56 residue. It finds application in the study of bacterial infection, neutropenia, severe burns, and chronic lung disease in cystic fibrosis (CF) [1]. Target: Others
MW: 377.82 D
From 1,440.00€ *
Review
12454 from 12463 pages