Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
H3R antagonist 2
Item number: TGM-T61603-100mg
Description: H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor antagonist with inhibitory effects on acetylcholinesterase, butyrylcholinesterase, and human monoamine oxidase B (hMAO B) with IC50 values of 180 nM, 880 nM, and 775 nM, respectively. With a Ki of 170 nM for hH3R, it demonstrates...
| MW: | 379.49 D |
From 1,440.00€
*
Hcyb1
Item number: TGM-T61617-100mg
Description: Hcyb1 is a potent and specific inhibitor of phosphodiesterase 2 (PDE2). It exhibits a high degree of selectivity for inhibiting PDE2A with an IC50 value of 0.57 µM. In addition, Hcyb1 displays over 250-fold selectivity against other recombinant members of the PDE family. Moreover, its pharmacological...
| MW: | 380.44 D |
From 867.00€
*
XN methyl pyrazole
Item number: TGM-T61619-100mg
Description: XN methyl pyrazole exhibits beneficial effects on diet-induced obesity and enhances energy expenditure in mice fed with a high-fat diet [1]. Target: Others
| MW: | 380.44 D |
From 1,440.00€
*
AChE/PDE4-IN-1
Item number: TGM-T61620-100mg
Description: AChE/PDE4-IN-1 (compound 12c) is a highly effective and specific dual inhibitor of PDE4 and AChE, with IC50 values of 0.28 µM for AChE and 1.88 µM for PDE4D. This compound shows notable potential in reducing neuroinflammation associated with Alzheimer's disease research [1]. Target: Others
| MW: | 380.48 D |
From 1,440.00€
*
GABAA receptor agonist 2
Item number: TGM-T61625-100mg
Description: GABAA receptor agonist 2 (compound 4c) is a highly potent compound that exhibits anti-depressive properties in classical mouse models of depression, such as the FST and TST. By binding to the GABA binding site on the GABAA receptor, it produces GABAergic effects. Notably, compound 4c holds promise for...
| MW: | 380.52 D |
From 1,440.00€
*
iMDK quarterhydrate
Item number: TGM-T61627-100mg
Description: iMDK quarterhydrate, a potent PI3K inhibitor, is effective in inhibiting the growth factor MDK (also known as midkine or MK) while demonstrating suppression of non-small cell lung cancer (NSCLC). In combination with a MEK inhibitor, iMDK quarterhydrate demonstrates cooperative inhibition of NSCLC...
| MW: | 380.91 D |
Please request pricing for this article.
Glutamate-5-kinase-IN-2
Item number: TGM-T60645-100mg
Description: Glutamate-5-kinase-IN-2 (compound 54) is a potent glutamate-5-kinase (G5K) inhibitor with an MIC of 4.2 µM, exhibiting G5K inhibition by promoting conformational changes at the L-glutamate binding site. Glutamate-5-kinase-IN-2 has potential for anti-TB research [1]. Target: Others
| MW: | 296.73 D |
From 1,440.00€
*
A4B17
Item number: TGM-T60647-100mg
Description: A4B17 is an inhibitor of androgen receptor N-terminal with potential for androgen-responsive prostate cancer treatment. Target: Others
| MW: | 297.27 D |
From 1,440.00€
*
IAB15
Item number: TGM-T60648-100mg
Description: IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1]. Target: Others
| CAS | 2987139-91-1 |
| MW: | 297.27 D |
From 1,440.00€
*
Monoamine Oxidase B inhibitor 1
Item number: TGM-T60656-100mg
Description: Monoamine Oxidase B inhibitor 1 is a potent, reversible, orally active, and selective monoamine oxidase B (MAO-B) inhibitor (IC50 = 0.02 nM) capable of crossing the blood-brain barrier (BBB). It exhibits antioxidant and anti-neuroinflammatory activities and can be used in the study of Parkinson's...
| MW: | 298.31 D |
From 1,440.00€
*
hMAO-B/MB-COMT-IN-2
Item number: TGM-T60658-100mg
Description: hMAO-B/MB-COMT-IN-2 is a dual inhibitor of MAO-B/MB-COMT with IC50s of 4.27 µM and 2.69 µM for hMAO-B and MB-COMT, respectively. hMAO-B/MB-COMT-IN-2 protects cells from oxidative damage and can be used in neurodegeneration disease research, such as Parkinson's Disease (PD) [1]. Target: Others
| MW: | 298.34 D |
From 1,440.00€
*
MS117
Item number: TGM-T60662-100mg
Description: MS117 is a first-in-class, cell-active, irreversible covalent inhibitor of protein arginine methyltransferase 6 (PRMT6) with an IC50 of 18 nM [1]. Target: Others
| MW: | 298.38 D |
From 1,023.00€
*