Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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VEGFR-2-IN-18
Item number: TGM-T61561-100mg
Description: VEGFR-2-IN-18 (Compound 15d) is a high-potency inhibitor of VEGFR-2, exhibiting an IC50 value of 60 nM. This compound effectively induces cell apoptosis and demonstrates significant antitumor properties [1]. Target: Others
| MW: | 376.8 D |
From 1,440.00€
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Vanin-1-IN-3
Item number: TGM-T61568-100mg
Description: Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC50 of 0.038 µM [1]. Target: Others
| MW: | 377.36 D |
From 1,440.00€
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Mt KARI-IN-1
Item number: TGM-T61569-100mg
Description: Mt KARI-IN-1 is a lead compound that demonstrates strong inhibitory activity towards Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), with a Ki value of 3.06 µM [1]. Target: Others
| MW: | 377.4 D |
From 1,440.00€
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MtTMPK-IN-5
Item number: TGM-T61573-100mg
Description: MtTMPK-IN-5 (compound 17) is a highly effective inhibitor of M. tuberculosis thymidylate kinase (Mtb TMPK), demonstrating remarkable enzyme inhibitory activity with an IC50 of 34 µM. Additionally, MtTMPK-IN-5 exhibits notable activity against M. tuberculosis, with an MIC of 12.5 µM. Given its potent...
| MW: | 377.44 D |
From 1,440.00€
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PD-L1-IN-1
Item number: TGM-T61574-100mg
Description: PD-L1-IN-1, a powerful PD-L1 inhibitor, demonstrated an IC50 of 115 nM. By forming a robust bond with the PD-L1 protein, PD-L1-IN-1 effectively suppressed tumor growth by enhancing the antitumor immune activity of peripheral blood mononuclear cells in co-cultures with PD-L1 expressing cancer cells (PC9...
| MW: | 377.44 D |
From 815.00€
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LasR-IN-2
Item number: TGM-T61581-100mg
Description: LasR-IN-2, a compound that inhibits the activity of LasR, forms hydrogen bonding with the TRY-56 residue. It finds application in the study of bacterial infection, neutropenia, severe burns, and chronic lung disease in cystic fibrosis (CF) [1]. Target: Others
| MW: | 377.82 D |
From 1,440.00€
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CDK/HDAC-IN-1
Item number: TGM-T61583-100mg
Description: CDK/HDAC-IN-1 exhibits potent inhibitory activity towards CDK2/4/6 and HDAC6, with IC50 values of 60.9 ± 2.9 nM, 276 ± 22.3 nM, 27.2 ± 4.2 nM, and 128.6 ± 0.4 nM, respectively. Target: Others
| MW: | 378.38 D |
From 1,440.00€
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AZD 2066 hydrate
Item number: TGM-T61708-25mg
Description: AZD 2066 hydrate is a selective, orally active, brain-penetrant mGluR5 antagonist with antinociceptive effects [1]. Target: Others
| MW: | 386.33 D |
From 1,364.00€
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AMS-17
Item number: TGM-T61709-100mg
Description: AMS-17 is a potent NLRP3 inhibitor that effectively suppresses microglia activation both in vitro and in vivo. Moreover, AMS-17 exhibits inhibitory effects on various cytokines, such as caspase-1, TNF-alpha, IL-1beta, and inducible nitric oxide synthase (iNOS), in N9 cells, making it a promising tool...
| MW: | 386.35 D |
From 1,440.00€
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Trk-IN-8
Item number: TGM-T61712-100mg
Description: Trk-IN-8, a powerful TRK inhibitor, demonstrates excellent potency against TRKAa, TRKA(G595R), and TRKC(G623R) with IC50 values of 0.42 nM, 0.89 nM, and 1.5 nM, respectively (WO2021115401A1, compound 3) [1]. Target: Others
| MW: | 386.36 D |
From 1,440.00€
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COX-2-IN-13
Item number: TGM-T61714-100mg
Description: COX-2-IN-13 (compound 13e) is a highly potent and selective COX-2 inhibitor with an impressive IC50 value of 0.98 µM. It exhibits strong anti-inflammatory activity and has shown favorable results in in vivo acute toxicity studies [1]. Target: Others
| MW: | 386.42 D |
From 1,440.00€
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Steroid sulfatase/17beta-HSD1-IN-1
Item number: TGM-T61716-100mg
Description: Steroid sulfatase/17beta-HSD1-IN-1 is a highly effective inhibitor of steroid sulfatase and 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) activities, with an IC50 value of 28 nM against cellular human steroid sulfatase. This compound holds significant potential for investigating...
| MW: | 386.42 D |
From 1,440.00€
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