Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

Go to the catalogs of TargetMol

12275 from 12311 pages
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Tubulin polymerization-IN-34
Tubulin polymerization-IN-34

Item number: TGM-T63849-100mg

Description: Tubulin polymerization-IN-34 is an inhibitor of [1,2] oxazolylisoindole-based microtubule polymerization and demonstrates high selectivity for marginal zone lymphoma VL51 cell lines. Target: Others
MW: 545.63 D
From 1,440.00€ *
Review
Cathepsin C-IN-3
Cathepsin C-IN-3

Item number: TGM-T63854-100mg

Description: Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM). Target: Others
MW: 546.57 D
From 1,440.00€ *
Review
M1069
M1069

Item number: TGM-T63856-100mg

Description: M1069 is a selective, orally active A2A/A2B diadenosine receptor antagonist that is more than 100-fold more selective than subtypes A1 and A3. M1069 antagonizes the immunosuppressive mechanisms induced by adenosine and exhibits antitumor effects. Target: Others
MW: 546.59 D
From 1,440.00€ *
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EGFR-IN-24
EGFR-IN-24

Item number: TGM-T63857-100mg

Description: EGFR-IN-24 is a potent inhibitor of EGFR and inhibits EGFR (del19/T790M/C797S) and EGFR (L858R/T790M/C797S). Target: Others
MW: 546.64 D
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I-BET282E
I-BET282E

Item number: TGM-T63858-100mg

Description: I-BET282E is a pan-inhibitor of eight BET bromodomains and shows selectivity for other representative bromodomain-containing proteins. It can act on eight BRD2 (BD1/BD2), BRD2 (BD1/BD), BRD3 (BD1/BD), and BRD4 (BD1/BD), with their pIC50 values ranging from 6.4 to 7.7. Target: Others
MW: 546.64 D
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Antiproliferative agent-4
Antiproliferative agent-4

Item number: TGM-T63864-100mg

Description: Antiproliferative agent-4 showed good anti-proliferative effects on some cancer cells. antiproliferative agent-4 inhibited tumour growth in nude mice and showed low toxicity. antiproliferative agent-4 reduced the mitochondrial membrane potential of EC109 cells and increased Antiproliferative agent-4...
MW: 547.04 D
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Review
GSK-3beta inhibitor 7
GSK-3beta inhibitor 7

Item number: TGM-T63866-100mg

Description: GSK-3beta inhibitor 7 is a GSK-3beta inhibitor (IC50: 5.25 µM) that acts by inserting into the ATP-binding pocket of GSK-3beta and forming hydrogen bonds. It exhibits a high rate of glucose uptake by hepatocytes (83.5%) and can be used to study various diseases such as cancer, diabetes, inflammation,...
MW: 547.47 D
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alpha5beta1 integrin agonist-1
alpha5beta1 integrin agonist-1

Item number: TGM-T63868-100mg

Description: alpha5beta1 integrin agonist-1 is an alpha5beta1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death. Target: Others
CAS 2756557-83-0
MW: 547.49 D
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Review
Anti-Abeta agent 1A
Anti-Abeta agent 1A

Item number: TGM-T63873-100mg

Description: Anti-Abeta agent 1A is a potent anti-amyloid-beta agent. Anti-Abeta agent 1A significantly inhibits LPS-induced IL-1beta, IL-6 and TNF-alpha levels and reduces H2O2-induced apoptosis in SH-SY5Y cells using the mitochondrial pathway, exhibiting antioxidant, anti-inflammatory, anti-Abeta toxicity and...
MW: 547.77 D
From 1,440.00€ *
Review
eeAChE-IN-1
eeAChE-IN-1

Item number: TGM-T63889-100mg

Description: eeAChE-IN-1 is a strong inhibitor of eeAChE (IC50: 23 nM). Target: Others
MW: 550.63 D
From 1,440.00€ *
Review
EGFR-IN-62
EGFR-IN-62

Item number: TGM-T63895-100mg

Description: EGFR-IN-62 is a potent inhibitor of EGFR kinase with IC50 values of 10 nM for L858R/T790 M, 29 nM for WT and 2 42 nM for L858R/T790 M/C797S. EGFR-IN-62 blocks the cell cycle of A549 and/or H1975 cells in G1/G0 phase and induces apoptosis and motility inhibition. EGFR-IN-62 effectively inhibited the...
MW: 551.64 D
From 1,440.00€ *
Review
VEGFR-2-IN-11
VEGFR-2-IN-11

Item number: TGM-T63900-100mg

Description: VEGFR-2-IN-11 is a potent inhibitor of VEGFR-2 (IC50: 60.27 nM) with an IC50 value of 60.27 nM, which induces apoptosis and has anticancer activity. Target: Others
MW: 552.49 D
From 1,440.00€ *
Review
12275 from 12311 pages