Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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Atidortoxumab
Item number: TGM-T82949-1mg
Description: Atidortoxumab is a human monoclonal antibody (IgG1kappa) targeting Staphylococcus aureus alpha toxin [1].
| CAS | 1939108-95-8 |
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ASGPR modulator-1
Item number: TGM-T82958-50mg
Description: Compound 5TJX (ASGPR modulator-1) is a macrocyclic compound utilized in the study of protein-protein interactions [1]. Target: Others
| CAS | 2052968-88-2 |
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ASB20123
Item number: TGM-T82961-50mg
Description: ASB20123, a CNP/ghrelin chimeric peptide, promotes bone growth and has potential research applications in growth disorders and dwarfism [1].
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ARUK2007145
Item number: TGM-T82964-50mg
Description: ARUK2007145 is a potent, cell-active inhibitor targeting both PI5P4Kalpha and PI5P4Kgamma isoforms with pIC50 values of 7.3 and 8.1, respectively [1]. Target: Others
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ARI-1
Item number: TGM-T82971-50mg
Description: ARI-1 is a receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor that binds to ROR1's extracellular Frizzled domain, effectively inhibiting aberrant ROR1 expression linked to non-small cell lung cancer (NSCLC) and EGFR-TKI-induced drug resistance. It modulates PI3K/AKT/mTOR signaling pathways...
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Aplyronine C
Item number: TGM-T82982-50mg
Description: Aplyronine C, an active compound, exhibits potent antitumor activity and demonstrates cytotoxicity against HeLa-S3 cells, with an IC50 value of 22 nM, suggesting potential use in cancer research [1].
| CAS | 151923-86-3 |
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Aplithianines A
Item number: TGM-T82984-50mg
Description: Aplithianines A effectively inhibits J-PKAcalpha with an IC50 value of 1 µM and displays higher potency against wild-type PKA, achieving an IC50 of 84 nM by competitively interacting with the ATP pocket [1]. Target: PKA
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AP 811 acetate
Item number: TGM-T82993-50mg
Description: AP 811 acetate is a selective antagonist of the atrial natriuretic peptide clearance receptor (ANP-CR, NPR3), with a high affinity (K_i = 0.48 nM) and over 20,000-fold selectivity for NPR3 compared to NPR1, effectively inhibiting ANP-induced pump stimulation [1] [2].
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Anzurstobart
Item number: TGM-T82994-10mg
Description: Anzurstobart, a fully human monoclonal anti-SIRPalpha antibody, is characterized by high-affinity binding and inhibition of the CD47-SIRPalpha interaction, which is known to suppress macrophage activity. Anzurstobart enhances macrophage-mediated phagocytosis of diffuse large B-cell lymphoma (DLBCL) cell...
| Keywords: | BMS-986351 , BMS986351 , CC95251 , CC-95251 |
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Antiviral agent 33
Item number: TGM-T82995-50mg
Description: Antiviral agent 33 (compound 1c), a double-stranded DNA (dsDNA) virus inhibitor, exhibits potent inhibitory activity with IC50 values of 0.0790 µM for VACV and 0.1572 µM for AdV5, and is a candidate for oral administration [1]. Target: Others
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Antitumor agent-107
Item number: TGM-T83009-50mg
Description: Antitumor agent-107 (compound 5h) is an anticancer agent exhibiting potent inhibitory activity against leukemia cell lines (GI50 = 0.32-1.34 µM) and demonstrating broad-spectrum antitumor effects across various human cancer cell lines (GI50 = 0.35-9.43 µM) [1]. Target: Others
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Antitumor agent-106
Item number: TGM-T83010-50mg
Description: Antitumor Agent-106 (Compound 42) is a potent anticancer compound, demonstrating significant inhibitory activity (IC50 = 4.2-6.6 µM) against lung and colon cancer cell lines [1]. Target: Others
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