Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
Biotin-PEG-amine (MW 3400)
Item number: TGM-T17551-100mg
Description: Biotin-PEG-amine (MW 3400) is a polyethylene glycol (PEG)-based linker compound used in the synthesis of PROTACs [1]. Target: Others. Smiles: NCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O.[n].[MW 3400]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the...
Please request pricing for this article.
Biotin-PEG-Biotin (MW 1000)
Item number: TGM-T17552-100mg
Description: Biotin-PEG-Biotin (MW 1000) is a PEG-derived PROTAC linker utilized in PROTAC synthesis [1]. Target: Others. Smiles: O=C(NCCOCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)CCCC[C@@H]3SC[C@]([C@]3([H])N4)([H])NC4=O.[n].[MW 1000]. References: An S, et al. Small-molecule PROTACs: An emerging and...
1,296.00€
*
Biotin-PEG-triethoxysilane (MW 1000)
Item number: TGM-T17553-100mg
Description: Biotin-PEG-triethoxysilane (MW 1000) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1]. Target: Others. Smiles: O=C(NCCC[Si](OCC)(OCC)OCC)NCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O.[n].[MW 1000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising...
Please request pricing for this article.
Biotin-PEG-triethoxysilane (MW 2000)
Item number: TGM-T17554-100mg
Description: Biotin-PEG-triethoxysilane (MW 2000) is a polyethylene glycol (PEG) derivative functionalized with triethoxysilane and biotin moieties, serving as a PEG-based linker for PROTAC synthesis to facilitate the targeted degradation of proteins of interest. Target: Others. Smiles:...
Please request pricing for this article.
Biotin-PEG-triethoxysilane (MW 5000)
Item number: TGM-T17555-100mg
Description: Biotin-PEG-triethoxysilane (MW 5000) is a PEG-based PROTAC linker used in PROTAC synthesis[1]. Target: Others. Smiles: O=C(NCCC[Si](OCC)(OCC)OCC)NCCOCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O.[n].[MW 5000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for...
Please request pricing for this article.
Dextromilnacipran
Item number: TGM-T2594-100mg
Description: Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor. Target: Serotonin Transporter, Norepinephrine. Smiles: C(N(CC)CC)(=O)[C@]1([C@@H](CN)C1)C2=CC=CC=C2. References: Leo RJ, Brooks VL. Curr Opin Investig Drugs. 2006 Jul,7(7):637-42.
| Keywords: | Levomilnacipran |
| Application: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 96847-55-1 |
| MW: | 246.35 D |
From 43.00€
*
Lumacaftor
Item number: TGM-T2595-100mg
Description: Lumacaftor (VRT 826809) is a CFTR modulator that corrects the folding and trafficking of CFTR protein. It enhances F508del-CFTR protein maturation in FRT cells (EC50: 100 nM). Target: CFTR, Autophagy. Smiles: Cc1ccc(NC(=O)C2(CC2)c2ccc3OC(F)(F)Oc3c2)nc1-c1cccc(c1)C(O)=O. References: Van Goor F, et al....
| Keywords: | VX-809, VRT 826809 |
| Application: | Targets cystic fibrosis transmembrane conductance regulator [EC:5.6.1.6] (CFTR, ABCC7) |
| CAS | 936727-05-8 |
| MW: | 452.41 D |
From 41.00€
*
Norgestrel
Item number: TGM-T2597-100mg
Description: Norgestrel (WY-3707) is a synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes....
| Keywords: | SH-70850, WY-3707, FH 122-A, SH-850 |
| Application: | Targets progesterone receptor (PGR, NR3C3) |
| CAS | 6533-00-2 |
| MW: | 312.45 D |
From 30.00€
*
AG490
Item number: TGM-T2600-100mg
Description: AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 µM). It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src. Target: Autophagy, EGFR, JAK, STAT. Smiles: C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2. References: Gazit A, et al....
| Keywords: | Zinc02557947, AG-490, Tyrphostin B42, Tyrphostin AG 490, AG 490 |
| Application: | JAK2 inhibitor |
| CAS | 133550-30-8 |
| MW: | 294.3 D |
From 41.00€
*
Vidofludimus
Item number: TGM-T2601-100mg
Description: Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH). Target: DNA/RNA Synthesis, Dehydrogenase, Interleukin. Smiles: COc1cccc(c1)-c1ccc(NC(=O)C2=C(CCC2)C(O)=O)c(F)c1. References: Kulkarni OP, et al. Am J Pathol. 2010, 176(6), 2840-2847.
| Keywords: | 4sc-101, SC12267 |
| Application: | Dihydroorotate dehydrogenase (DHODH) inhibitor |
| CAS | 717824-30-1 |
| MW: | 355.36 D |
From 51.00€
*
Spebrutinib
Item number: TGM-T2603-100mg
Description: Spebrutinib (LMK-435) is an orally bioavailable, selective inhibitor of Bruton's agammaglobulinemia tyrosine kinase (BTK), with potential antineoplastic activity. Target: Src, BTK. Smiles: COCCOc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1. References: Evans E, et al. ASH Annual Meeting, 2011 San Diego,...
| Keywords: | AVL-292, LMK-435, CC-292 |
| Application: | Targets Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (BTK) |
| CAS | 1202757-89-8 |
| MW: | 423.44 D |
From 34.00€
*
1-EBIO
Item number: TGM-T2604-100mg
Description: 1-EBIO (1-EBIO) is a calium channel agonist. Target: Calcium Channel. Smiles: CCn1c2ccccc2[nH]c1=O. References: Walker SD, et al. Br J Pharmacol. 2001 Dec,134(7):1548-54.
| CAS | 10045-45-1 |
| MW: | 162.19 D |
From 29.00€
*