Products from TargetMol

TargetMol

TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.

More information at: www.targetmol.com

Go to the catalogs of TargetMol

12256 from 12274 pages
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JAK-IN-19
JAK-IN-19

Item number: TGM-T63026-100mg

Description: JAK-IN-19 is a potent JAK inhibitor with pIC50 values of 7.2 for PBMC (IFNgamma) and 7.7 for HLF (Eotaxin). The compound also exhibits pIC50 values of 7.0 for VEGFR2 and 5.8 for Aurora B. Target: Others
MW: 469.59 D
From 1,440.00€ *
Review
Antibacterial agent 66
Antibacterial agent 66

Item number: TGM-T63027-100mg

Description: Antibacterial agent 66 (Compound 6q) is a trifluoromethylpyridine 1,3,4-oxadiazole derivative active against Xanthomonas oryzae pv. oryzae (Xoo) (EC50: 7.2 µg/mL). Target: Others
MW: 469.79 D
From 1,440.00€ *
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KRAS G12D inhibitor 12
KRAS G12D inhibitor 12

Item number: TGM-T63028-100mg

Description: KRAS G12D inhibitor 12 is an effective inhibitor of KRAS G12D. The Ras protein family is an important intracellular signaling molecule, which plays an important role in growth and development. KRAS G12D inhibitor 12 has the potential to perform KRAS G12D-mediated cancer studies. Target: Others
MW: 469.9 D
From 1,440.00€ *
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TIM-3-IN-1
TIM-3-IN-1

Item number: TGM-T63029-100mg

Description: TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer. Target: Others
MW: 469.9 D
From 1,440.00€ *
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P-gp modulator 2
P-gp modulator 2

Item number: TGM-T63032-100mg

Description: P-gp modulator 2 (Compound 27) is a potent competitive and metabotropic modulator of P-glycoprotein (P-gp). Target: Others
MW: 470.32 D
From 1,440.00€ *
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MsbA-IN-4
MsbA-IN-4

Item number: TGM-T63033-100mg

Description: MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 µM). Target: Others
MW: 470.33 D
From 1,440.00€ *
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IDO1-IN-13
IDO1-IN-13

Item number: TGM-T63034-100mg

Description: IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM. It inhibits cell IDO1 with an EC50 of 30 nM for HeLa cells and reduces the kyn/trp ratio by 51% in SK-OV-3 xenograft tumor tissue. Target: Others
MW: 470.34 D
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Anti-inflammatory agent 18
Anti-inflammatory agent 18

Item number: TGM-T63473-100mg

Description: Anti-inflammatory agent 18 inhibits NO activity (IC50: 15.94 µM) and has an inhibitory effect on the late inflammatory response induced by HMGB1 and can be used to study late inflammatory diseases such as coronavirus disease (COVID-19), sepsis, etc. Target: Others
MW: 506.71 D
From 1,440.00€ *
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PI3Kalpha-IN-8
PI3Kalpha-IN-8

Item number: TGM-T63477-100mg

Description: PI3Kalpha-IN-8 is a selective inhibitor of PI3Kalpha (IC50: 0.012 µM). PI3Kalpha-IN-8 increases intracellular levels of reactive oxygen species, decreases mitochondrial membrane potential, and induces apoptosis. Target: Others
MW: 507.42 D
From 1,440.00€ *
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Antifungal agent 12
Antifungal agent 12

Item number: TGM-T63478-100mg

Description: Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects. Target: Others
MW: 507.51 D
From 1,440.00€ *
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TCMDC-135051 hydrochloride
TCMDC-135051 hydrochloride

Item number: TGM-T63488-100mg

Description: TCMDC-135051 hydrochloride is a potent, highly selective, low off-target toxicity inhibitor of the protein kinase PfCLK3. TCMDC-135051 hydrochloride blocks the trophozoite to lysosome transition, disrupts transcription and inhibits transmission to mosquito vectors, exhibiting an antiparasitic effect...
MW: 508.05 D
From 1,137.00€ *
Review
MtTMPK-IN-8
MtTMPK-IN-8

Item number: TGM-T63491-100mg

Description: MtTMPK-IN-8 is a moderately potent inhibitor of Mycobacterium thymidylate kinase (MtbTMPK) with no significant cytotoxicity, exhibiting submicromolar activity (MICs = 0.78-9.4 µM) against Mycobacterium and capable of being used in the study of tuberculosis. Target: Others
MW: 508.48 D
From 1,440.00€ *
Review
12256 from 12274 pages