Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
No results were found for the filter!
LDS-751
Item number: TGM-T19022-1mg
Description: LDS-751 is a stain of nucleic acid. Target: Others. Smiles: [O-][Cl](=O)(=O)=O.CC[n+]1c(\C=C\C=C\c2ccc(cc2)N(C)C)ccc2cc(ccc12)N(C)C
| MW: | 471.98 D |
From 44.00€
*
Cilastatin
Item number: TGM-T2583-100mg
Description: Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also...
| Keywords: | MK0791 |
| Application: | Targets membrane dipeptidase [EC:3.4.13.19] (DPEP) |
| CAS | 82009-34-5 |
| MW: | 358.45 D |
From 30.00€
*
Bedaquiline
Item number: TGM-T2585-100mg
Description: Bedaquiline (R207910) is an anti-tuberculosis drug which selectively inhibit the mycobacterial energy metabolism i.e. ATP synthesis and found to be effective against all states of Mycobacterium tuberculosis. Target: Antibiotic, Antibacterial. Smiles:...
| Keywords: | R207910, TMC207 |
| Application: | Targets F-type H+-transporting ATPase subunit c (ATPF0C, atpE) |
| CAS | 843663-66-1 |
| MW: | 555.5 D |
From 45.00€
*
Dolasetron Mesylate hydrate
Item number: TGM-T2589-1mL
Description: Dolasetron Mesylate hydrate (Dalasetron Mesylate Hydrate) , a selective serotonin receptor antagonist, competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. Target: 5-HT Receptor. Smiles:...
| Keywords: | Dalasetron Mesylate Hydrate |
| CAS | 878143-33-0 |
| MW: | 438.49 D |
From 29.00€
*
Vismodegib
Item number: TGM-T2590-100mg
Description: Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 µM), ABCG2 (IC50: 1.4 µM). Target: ABC, Autophagy, Hedgehog/Smoothened. Smiles: ClC=1C(=CC(NC(=O)C2=C(Cl)C=C(S(C)(=O)=O)C=C2)=CC1)C3=CC=CC=N3. References: Scales SJ, et al. Mechanisms of Hedgehog...
| Keywords: | RG 3616, GDC-0449, Erivedge |
| Application: | Targets smoothened (SMO) |
| CAS | 879085-55-9 |
| MW: | 421.3 D |
From 37.00€
*
Veliparib
Item number: TGM-T2591-100mg
Description: Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy. Target: PARP, Autophagy. Smiles: C(N)(=O)C1=C2C(N=C(N2)[C@@]3(C)CCCN3)=CC=C1. References: Donawho CK, et al. ABT-888, an orally active poly(ADP-ribose)...
| Keywords: | ABT-888, NSC 737664 |
| Application: | Antineoplastic (enhancer), PARP inhibitor |
| CAS | 912444-00-9 |
| MW: | 244.29 D |
From 49.00€
*
Ropinirole hydrochloride
Item number: TGM-T2592-100mg
Description: Ropinirole hydrochloride (SKF-101468A) is a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole hydrochloride (SKF-101468A) is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with antiparkinsonian property. Target: Dopamine Receptor. Smiles:...
| Keywords: | SKF 101468 hydrochloride, SKF-101468A, Ropinirole HCl |
| Application: | Targets dopamine receptor D2 (DRD2) |
| CAS | 91374-20-8 |
| MW: | 296.84 D |
From 35.00€
*
Amine-PEG-amine (MW 2000)
Item number: TGM-T17390-100mg
Description: Amine-PEG-amine (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in PROTAC synthesis, facilitating targeted protein degradation [1]. Target: Others. Smiles: NCCOCCN.[MW 2000].[n]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development...
Please request pricing for this article.
Amine-PEG-amine (MW 3400)
Item number: TGM-T17392-100mg
Description: Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1]. Target: Others. Smiles: NCCOCCN.[MW 3400].[n]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted...
Please request pricing for this article.
Amine-PEG-amine (MW 35000)
Item number: TGM-T17393-100mg
Description: Amine-PEG-amine (MW 35000), a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1]. Target: Others. Smiles: NCCOCCN.[MW 35000].[n]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018...
Please request pricing for this article.
Amine-PEG-amine (MW 5000)
Item number: TGM-T17394-5mg
Description: Amine-PEG-amine (MW 5000) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs) [1]. Target: Others. Smiles: NCCOCCN.[MW 5000].[n]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted...
30.00€
*
Amine-PEG-CH2COOH (MW 5000)
Item number: TGM-T17395-100mg
Description: Amine-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1]. Target: Others. Smiles: NCCOCC(O)=O.[n].[MW 5000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the...
| MW: | 5000 D |
Please request pricing for this article.