Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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m-PEG-mal (MW 20000)
Item number: TGM-T18094-100mg
Description: m-PEG-mal (MW 20000) is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCNC(CCN1C(C=CC1=O)=O)=O.[n].[MW 20000]. References: An S, et al....
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m-PEG-mal (MW 30000)
Item number: TGM-T18095-100mg
Description: m-PEG-mal (MW 30000) is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCNC(CCN1C(C=CC1=O)=O)=O.[n].[MW 30000]....
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m-PEG-mal (MW 5000)
Item number: TGM-T18096-100mg
Description: m-PEG-mal (MW 5000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCNC(CCN1C(C=CC1=O)=O)=O.[n].[MW 5000]. References: An S, et al. Small-molecule PROTACs:...
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m-PEG-NH2 (MW 10000)
Item number: TGM-T18098-100mg
Description: m-PEG-NH2 (MW 10000) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: NCCOCCOC.[n].[MW 10000]. References: An S,...
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m-PEG-NH2 (MW 2000)
Item number: TGM-T18099-100mg
Description: m-PEG-NH2 (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: NCCOCCOC.[n].[MW 2000]. References: An S,...
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m-PEG-NH2 (MW 5000)
Item number: TGM-T18101-100mg
Description: m-PEG-NH2 (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: NCCOCCOC.[n].[MW 5000]. References: An S,...
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m-PEG-NHS ester (MW 10000)
Item number: TGM-T18102-100mg
Description: m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker used for synthesizing PROTACs[1]. Target: Others. Smiles: COCCOCC(ON1C(CCC1=O)=O)=O.[MW 10000].[n]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine....
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m-PEG-NHS ester (MW 20000)
Item number: TGM-T18103-100mg
Description: rm-PEG-NHS ester (MW 20000) is a PEG-based PROTAC linker utilized for the synthesis of PROTACs[1]. Target: Others. Smiles: COCCOCC(ON1C(CCC1=O)=O)=O.[MW 20000].[n]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs....
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m-PEG-NPC (MW 20000)
Item number: TGM-T18105-100mg
Description: m-PEG-NPC (MW 20000) is a PEG-based linker for PROTACs, joining two essential ligands to facilitate the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOC(OC1=CC=C([N+]([O-])=O)C=C1)=O.[n].[MW...
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m-PEG-OH (MW5000)
Item number: TGM-T18106-100mg
Description: m-PEG-OH (MW5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Target: Others. Smiles: COCCOCCO.[n].[MW 5000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018...
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m-PEG-Succinimidyl Succinate (MW 5000)
Item number: TGM-T18107-100mg
Description: m-PEG-Succinimidyl Succinate (MW 5000) is a polyethylene glycol (PEG)-based linker with succinimidyl succinate functionality, mainly used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. Target: Others. Smiles: O=C(ON1C(CCC1=O)=O)CCC(OCCOCCOC)=O.[n].[MW 5000]. References: An S, et al....
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m-PEG-thiol (MW 10000)
Item number: TGM-T18108-100mg
Description: m-PEG-thiol (MW 10000) is a PEG-based linker for PROTACs that joins two critical ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCS.[MW 10000].[n]. References: An S, et al....
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