Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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m-PEG-azide (MW 10000)
Item number: TGM-T18082-100mg
Description: m-PEG-azide (MW 10000), a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCN=[N+]=[N-].[n].[MW 10000]. References: An S, et al....
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m-PEG-azide (MW 2000)
Item number: TGM-T18083-100mg
Description: m-PEG-azide (MW 2000) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating the selective degradation of target proteins through the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCN=[N+]=[N-].[n].[MW 2000]. References: An S, et al. Small-molecule...
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m-PEG-azide (MW 20000)
Item number: TGM-T18084-100mg
Description: m-PEG-azide (MW 20000) is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands necessary for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCN=[N+]=[N-].[n].[MW...
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m-PEG-azide (MW 5000)
Item number: TGM-T18085-100mg
Description: m-PEG-azide (MW 5000) is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands to enable selective protein degradation via the ubiquitin-proteasome system in cells. Target: Others. Smiles: COCCOCCN=[N+]=[N-].[n].[MW 5000]. References: An S, et al. Small-molecule PROTACs:...
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m-PEG-Butyraldehyde (MW 5000)
Item number: TGM-T18086-100mg
Description: m-PEG-Butyraldehyde (MW 5000) is a polyethylene glycol (PEG)-based linker compound used in PROTAC synthesis [1]. Target: Others. Smiles: COCCOCCCC=O.[n].[MW 5000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs....
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m-PEG-CH2COOH (MW 2000)
Item number: TGM-T18087-100mg
Description: m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1]. Target: Others. Smiles: OC(COCCOC)=O.[n].[MW 2000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct,36:553-562
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m-PEG-CH2COOH (MW 20000)
Item number: TGM-T18088-100mg
Description: m-PEG-CH2COOH (MW 20000) functions as a PEG-based PROTAC linker used in the synthesis of PROTACs[1]. Target: Others. Smiles: OC(COCCOC)=O.[n].[MW 20000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018...
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m-PEG-CH2COOH (MW 5000)
Item number: TGM-T18089-100mg
Description: m-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG) derived PROTAC linker used in the synthesis of PROTACs. [1]. Target: Others. Smiles: OC(COCCOC)=O.[n].[MW 5000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs....
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m-PEG-Lys-NHS ester (MW 20000)
Item number: TGM-T18090-100mg
Description: m-PEG-Lys-NHS ester (MW 20,000) is an alkyl/ether-based PROTAC linker commonly used in PROTAC synthesis[1]. Target: Others. Smiles: COCCOCCOC(NCCCC[C@H](NC(OCCOCCOC)=O)C(ON1C(CCC1=O)=O)=O)=O.[n].[n].[MW 20000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the...
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m-PEG-Lys-NHS ester (MW 40000)
Item number: TGM-T18091-100mg
Description: m-PEG-Lys-NHS ester (MW 40000) is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs [1]. Target: Others. Smiles: COCCOCCOC(NCCCC[C@H](NC(OCCOCCOC)=O)C(ON1C(CCC1=O)=O)=O)=O.[n].[n].[MW 40000]. References: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the...
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m-PEG-mal (MW 10000)
Item number: TGM-T18092-100mg
Description: m-PEG-mal (MW 10000) is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCNC(CCN1C(C=CC1=O)=O)=O.[n].[MW 10000]....
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m-PEG-mal (MW 2000)
Item number: TGM-T18093-100mg
Description: m-PEG-mal (MW 2000) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. Target: Others. Smiles: COCCOCCNC(CCN1C(C=CC1=O)=O)=O.[n].[MW 2000]. References: An S, et al. Small-molecule PROTACs: An...
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