Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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FGFR4-IN-16
Item number: TGM-T79880-50mg
Description: FGFR4-IN-16 (CY-15-2) is a covalent inhibitor of FGFR-4, employed in cancer research [1]. Target: FGFR
| CAS | 1970120-44-5 |
| MW: | 685.56 D |
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CDK7-IN-25
Item number: TGM-T79881-50mg
Description: CDK7-IN-25 (CY-16-1) is a highly potent CDK7 inhibitor with an IC50 of less than 1nM, used in cancer research [1]. Target: CDK
| CAS | 2009209-60-1 |
| MW: | 560.65 D |
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JAK-IN-31
Item number: TGM-T79882-50mg
Description: JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of =0.01 µM for JAK1, =0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and =0.01 µM for Tyk2, indicating potent activity across these targets. It is utilized in cancer research [1]. Target: JAK
| CAS | 2597016-88-9 |
| MW: | 465.55 D |
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9-Chloromethyl-10-hydroxy-11-F-Camptothecin
Item number: TGM-T79883-50mg
Description: 9-Chloromethyl-10-hydroxy-11-F-Camptothecin, a novel derivative of camptothecin, functions as a DNA topoisomerase I (Topo I) inhibitor with potential applications in anticancer research [1]. Target: Topoisomerase
| CAS | 2414594-22-0 |
| MW: | 428.84 D |
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Inflexuside A
Item number: TGM-T75616-50mg
Description: Inflexuside A, an abietane diterpenoid isolated from the aerial parts of Isodon inflexus, and Inflexuside B significantly inhibit lipopolysaccharide (LPS)-activated NO production (NO Synthase) in RAW264.7 macrophages [1]. Target: Others
| CAS | 1395048-85-7 |
| MW: | 498.61 D |
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Salviandulin E
Item number: TGM-T75617-50mg
Description: Salviandulin E, a diterpenoid isolated from Salvia leucantha CAV., exhibits antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites, demonstrating an IC50 value of 0.72 µg/mL [1] [2]. Target: Others
| CAS | 158994-32-2 |
| MW: | 352.34 D |
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Sorbifolin
Item number: TGM-T75618-50mg
Description: Sorbifolin, a flavone glucoside isolated from Pterogyne nitens, exhibits myeloperoxidase (MPO) inhibitory and radical scavenging activities. This compound functions as an effective MPO inhibitor, demonstrated by its IC 50 value of 19.2 nM [1]. Target: Others
| CAS | 23130-22-5 |
| MW: | 300.26 D |
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Aristololactam IIIa
Item number: TGM-T75619-50mg
Description: Aristololactam IIIa demonstrates substantial inhibition of superoxide anion generation and elastase release, exhibiting IC50 values of 0.12 and 0.20 µg/mL, respectively [1]. Target: Others
| CAS | 97399-89-8 |
| MW: | 279.25 D |
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(+)-Oxypeucedanin methanolate
Item number: TGM-T75620-50mg
Description: (+)-Oxypeucedanin methanolate (compound 9) is a natural inhibitor of prostaglandin E2 production [1]. Target: Others
| CAS | 52939-12-5 |
| MW: | 318.32 D |
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Secalonic acid D
Item number: TGM-T75621-50mg
Description: Secalonic acid D, a toxic compound effective against tumor cells, is derived from the metabolites of Aspergillus aculeatus. It operates by activating GSK3-beta and degrading beta-catenin, consequently down-regulating c-Myc expression, arresting the cell cycle at the G1 phase, and inducing cell apoptosis...
| CAS | 35287-69-5 |
| MW: | 638.57 D |
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beta-Apopicropodophyllin
Item number: TGM-T75622-50mg
Description: beta-Apopicropodophyllin, a natural product isolated from Hyptis wticillata, promotes apoptosis through mechanisms including microtubule disruption, DNA damage, cell cycle arrest, and ER stress. This compound holds potential for cancer research applications [1]. Target: Others
| CAS | 477-52-1 |
| MW: | 396.39 D |
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Sadopeptins A
Item number: TGM-T75623-50mg
Description: Sadopeptins A, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1]. Target: Others
| MW: | 1026.21 D |
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